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Biomedical subjects

S Włoch

Publications and source records attributed to S Włoch.

At least 19 recordsLinked to original sources

Non-insulin-dependent diabetes mellitus as a risk factor for denture stomatitis.

The prevalence of denture stomatitis as well as the frequency of isolation of Candida species and their density on the palatal mucosa have been compared in 70 acrylic denture-wearers suffering from non-insulin-dependent diabetes mellitus (NIDDM) versus 58 acrylic denture-wearers with normal glucose metabolism. The adherence of C. albicans to palatal epithelial cells in vitro was also assessed in both groups. The patients with NIDDM had a significantly higher prevalence of denture stomatitis compared with the controls. The frequency of Candida colonization was increased in diabetics, but not significantly. According to the imprint culture technique, the density of Candida species was significantly higher in patients with NIDDM compared with the controls. The adherence of C. albicans to palatal epithelial cells from patients with NIDDM showed a significant increase compared with that observed in cells collected from the controls. This study supports the view that NIDDM predisposes to Candida-associated denture stomatitis.

Acrylic Resins

[Dynamics of morphological and cytochemical changes in the placenta following cadmium chloride intoxication].

The experiments carried out for the study aimed at determining the prenatal sensitivity to cadmium in the aspect of beth morphological and functional condition of placenta. The experiments were carried out on 80 pregnant female rats divided into three experimental groups and a control one. The experimental animals were daily administered, intragastrically, aqueous solution of cadmium chloride, from the 7th to the 19th day of pregnancy, in doses differing between the experimental groups: 2, 10 and 22 mg of CdCl2 per kilogram of body weight, respectively. The animals were decapitated on the 21st day of pregnancy. Placenta sections, besides hematoxylin and eosin staining, were examined for the activity of the following enzymes: succinic dehydrogenase (SDH) E.C.1.3.99.1., lactate dehydrogenase (LDH) E.C.1.1.1.27., NADH-tetrazole reductase (NADH-t.r.), without a catalog number, and their glycogen reaction was checked. The results of the experiments proved cadmium chloride to cause considerable damage to the enzymatic apparatus of placenta, leading to energy deficit in the cells of both the fetal and the maternal part of this organ. The multienzymatic changes observed preceded the morphologic ones by far.

Animals

[Examination of activity of certain phosphatases in the placenta of female rats exposed to cadmium].

The enzymatic examinations were carried out to determine, as early as possible, the functional changes in cells of fetal and maternal part of placenta, as well as pointing out those elements which were the most susceptible to cadmium toxic action. The experiments were carried out on 80 pregnant female rats which were divided into three experimental groups and a control one. The experimental animals were daily administered, intragastrically, aqueous solution of cadmium chloride, between the 7th and 19th day of pregnancy, in doses depending on experimental groups: 2, 10 and 20 mg of CdCl2 per kilogram of body weight, respectively, the animals were killed on the 21st day of pregnancy. Placenta sections were determined for activity of adenosinetriphosphatase stimulated by Mg++ ions (ATP-ase Mg++) E.C.3.6.1.3., and acid phosphatase (AcP) E.C.3.1.3.2. When administered to pregnant females, cadmium chloride was proved to cause a considerable impairment of active transport through biological membranes in placenta, which is indicated by a decrease of reactivity to Mg++ ions stimulated ATP-ase; and an increase in intracellular catabolic processes, which in turn is shown by an increase in reactivity to acid phosphatase. The fetal part of the placenta proves to be more susceptible to the lesion causing activity of cadmium than the maternal part of this organ.

Acid Phosphatase

[The condition of teeth in adult population aged 35-44 years living in a small town and in villages in the Province of Poznan].

In an epidemiological study the condition of teeth was assessed in 120 subjects aged 35-44 years living in Sroda Wielkopolska and villages around it. Group I (60 subjects) lived in the town and group II (60 subjects) came from villages. Each group contained 30 women and 30 men. A high prevalence of caries was found, (99.16% for the whole studied population) with the mean DMF value 16.79%. The highest DMF values were found in group II in women--21.66. These high values of DMF were due to a great number of carietic teeth, teeth removed because of caries, and a relatively small number of teeth with fillings. Slight developmental disturbances of the enamel were observed.

Adult

[Dental caries in children aged 7 and 12 years in the Province of Poznan].

The authors present the results of stomatological epidemiological studies in the Province of Poznán in 1987 for establishing the prevalence of dental caries in children aged 7 and 12 years. The assessment was done using the index of caries prevalence, value of the mean DMF-H and dmf-h indices, and their components. In both studied age groups a high prevalence of caries was found, reaching 90% in children aged 7, years and 80% in those aged 12 years. The intensity of caries in children aged 7 years measured by the index DMF-h+dmf-h (mixed teeth) was high--4.99. The intensity of caries was higher in children from rural areas (5.43) than in those from urban areas (4.455). The mean value of DMF-h was 0.49 for the whole population studied, and 0.41 for urban children and 0.56 for rural children. The mean DMF-z value in children aged 12 years was below 3.0 (2.34), and it was higher in children from rural areas (2.96) than in those from urban areas. The values of these indices were influenced mainly by high mean numbers of milk and permanent teeth with active caries. In the studied population a small number of filled teeth was noted.

Child

[Requirements for prosthetic treatment of adults aged 35-44 years in the Province of Poznan].

Stomatological examination of a group of 120 adults aged 35-44 years living in the Province of Poznań showed considerable loss of teeth (mean loss--7 in towns and 9 in villages). It was found that a small percent of these adults had prosthetic replacements. The greatest requirements were for partial lower prostheses and upper partial prostheses. Generally, greater loss of teeth was found in the rural population compared with the urban one.

Adult

Placental phospholipase A2 activities in pre-eclampsia.

Phospholipase A2 activity was significantly increased in placental homogenates from 22 patients with preeclampsia in comparison to placental homogenates from women with uncomplicated pregnancy. Such an abnormality may be responsible for a altered release of free arachidonic acid, thus playing a major role in the pathogenesis of this syndrome.

Adolescent