[Saddle embolism of the aortic bifurcation caused by parts of a cardiac myxoma].
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Adult↗
Biomedical subjects
S Walgenbach
Publications and source records attributed to S Walgenbach.
[Hyperparathyroidism. Clinical course and results of operative therapy].
Between 1974 and 1981 27 patients underwent parathyroid exploration for hyperparathyroidism at the Department of Surgery, University of Cologne. 18 patients could be reexamined postoperatively. Parathormone levels, serum calcium, serum phosphates and alkaline phosphatase in serum were measured. Recurrence of hyperparathyroidism did not occur. In our patients the excision of a single parathyroid adenoma and subtotal respectively total parathyroidectomy for parathyroid hyperplasia was the adequate therapy of hyperparathyroidism. Up to 82 months postoperatively the patients were without complaints. The determination of parathormone is an important factor in the follow-up program.
Female↗
Lipoprotein and apoprotein values in coronary angiography patients.
In this study the lipoprotein and apoprotein patterns of patients with coronary artery disease were evaluated. The patient population consisted of 179 men who underwent coronary arteriography. On the basis of the results of coronary arteriography these patients were subdivided into a control group (score 0) with normal arteriograms and three groups each having coronary artery disease (CAD) of increasing severity (scores 1 to 3). The patients with coronary artery disease had significantly higher plasma concentrations of total cholesterol, LDL cholesterol, triglycerides and apolipoprotein B (apo B) than the controls. HDL cholesterol as well as apolipoprotein A-I (apo A-I) were significantly lower in patients with coronary artery disease. However, no difference was found in apolipoprotein A-II (apo A-II) values. Apo B and LDL cholesterol increased with the degree of coronary atherosclerosis. In the discriminant function analysis, apo B was the best separating parameter between control patients and CAD patients (scores 1-3).
Apoproteins↗
Hyperlactacidaemia in isolated hyperthermic perfusion of tumour bearing rat limbs: a study of feasibility using a novel infusion solution.
PURPOSE: In a methodological study the applicability of hyperlactacidaemia in isolated hyperthermic perfusion of tumour-bearing rat limbs was investigated. METHODS: In 50 Sprague Dawley rats, DS-sarcoma growth was initiated on the right food dorsum by subcutaneous injection of 0.5 ml ascites cells. In the anaesthetized animals isolated limb perfusion was performed under steady state conditions for 60min using a miniature equipment. Thereafter tumour volume was measured daily. (a) Investigation of feasability: 40 rats were allocated to four groups. Group I: Normothermic perfusion at 38 degrees C, n = 10; Group II: Hyperthermic perfusion at 40-41 degrees C, n = 10; Group III: Normothermic perfusion at 38 degrees C and hyperlactacidaemia of 10 mmol/l, n = 10; Group IV: Hyperthermic perfusion at 40-41 degrees C and hyperlactacidaemia of 10 mmol/l, n = 10. (b) Investigation of survival and histological changes: In group V hyperthermic perfusion at 40-41 degrees C and hyperlactacidaemia of 10 mmol/l, n = 10 was performed. After the animals had died, hip disarticulation of the tumour-bearing limb was performed for histological examination. RESULTS: Normothermic and hyperthermic perfusion of tumour-bearing rat limbs using miniature equipment was feasible and tolerated by the animals. Regional hyperlactacidaemia of 10 mmol/l could be maintained throughout the perfusions. After combined treatment with hyperthermia and hyperlactacidaemia, tumour volume decreased and extensive tumour necrosis occurred, while in other animals aggressive tumour growth with bone infiltration could be observed. CONCLUSIONS: The present study demonstrates the applicability of hyperlactacidaemia in hyperthermic isolated limb perfusion in the rat and proved a tumour growth delay due to an induction of tumour necrosis thereafter. Further investigations in other tumour entities and experimental models are required to confirm this impressive therapeutic effect of hyperthermia in combination with hyperlactacidaemia.
Animals↗
The electrostimulation test for intraoperative control of vagotomy.
A prospective randomized study was made of the Burge-Vane intraoperative electrostimulation test (EST) following selective proximal vagotomy for duodenal ulcer. Histologically proven nerve fibres were demonstrated by EST in 6 of 50 patients. The postoperative acid values and the ulcer recurrence rate were compared in these 50 patients and in 50 who did not undergo EST. The postoperative acid values did not differ significantly between these two groups. Ulcer recurred in 16% of the EST and 14% of the non-EST group during 6-8 year follow-up. Use of EST thus did not influence the results in this trial.
Adult↗