Biomedical subjects
S Walther-Larsen
Publications and source records attributed to S Walther-Larsen.
[Pediatric anesthesia in Denmark--a debate on the organization of pediatric anesthesia/surgery, intensive care and pain relief].
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[The significance of recurrent nerve paresis for the operability of lung cancer].
The object of the study was a reassessment of the old but still widely accepted apophthegm that recurrent nerve palsy prohibits surgery in patients with pulmonary cancer. Out of 1,279 patients admitted over a 10-year period with proven or suspected pulmonary cancer, 23 were found to have recurrent nerve paralysis. Eleven of these were found inoperable by the preoperative work-up while 12 underwent thoracotomy. In three cases it was possible to perform a left upper lobectomy, which was considered to be radical both macro- and microscopically in two cases. The conclusion is that paralysis of the recurrent nerve, as might be foreseen, gravely worsens the prognosis, inverting the usual ratio of 80:20 between resections and exploratory thoracotomies. This, however, leaves a small group which will benefit from surgery, particularly considering the lack of alternative therapy.
Arterial desaturation in healthy children during and after minor surgery.
Pulse oximetry (PO) was applied to 79 otherwise healthy children during and after minor ENT surgery under general anaesthesia in private practice. The PO data were not available to the anaesthetist unless desaturation to less than or equal to 85% was present for greater than or equal to 30 s. This occurred in 12 and 9 cases during anaesthesia and recovery, respectively, only 8 and 5 cases, respectively, being diagnosed clinically. Desaturation during and after anaesthesia was more common in children undergoing adenoidectomy than during procedures for which endotracheal intubation was not performed. During recovery, desaturation was more likely to occur in the same patients again. Lower values of SaO2 were found in younger children and in children resisting or crying at induction. There was a (weak) negative correlation between SaO2 and HR. As clinically undiagnosed desaturation occurs even in healthy children undergoing minor surgical procedures, a more widespread use of PO during and after anaesthesia may be advisable.
Measurement of central venous pressure after open heart surgery and effect of positive end expiratory pressure.
Central venous pressure (CVP) recorded on electronic equipment (E-CVP) is compared with CVP measured by water column (W-CVP) in 50 patients after coronary bypass surgery without prior pulmonary symptoms. We find a statistically significant, but clinically insignificant, difference between E-CVP and W-CVP. Treatment with 10 cm H2O positive end expiratory pressure (PEEP) causes a significant rise in CVP by increasing intrathoracic pressure, but as changes in CVP rather than a given value are of greater importance in the daily clinical situation, we do not consider it clinically important to interrupt treatment with PEEP in as much as only small changes in CVP are induced after application of PEEP.
[Nodular pulmonary amyloidosis].
Amyloidosis limited to the lower respiratory tract is a relatively rare condition. It may be either tracheobronchial or parenchymal, and the parenchymal form may be either nodular or diffuse. A case of nodular pulmonary amyloidosis is presented.
Misplacement of subclavian venous catheters: importance of head position and choice of puncture site.
We have investigated the frequency of misplacement of subclavian catheters in 200 consecutive patients admitted to the Intensive Care Unit. The patients were allocated randomly to an attempt at infraclavicular cannulation of the right or left subclavian vein with the head turned either towards or away from the selected side, giving four groups. Catheterization was successful in 185 (92.5%) patients. Misplacement into the internal jugular vein occurred in 10 (5.4%) patients. No statistically significant difference (P less than 0.05) was demonstrated between the four groups.
Reliability of central venous pressure measured by water column.
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Occlusive dressing versus petroleum gauze on drainage wounds.
Two different wound dressings were tested on human drainage wounds. Improved healing was observed under an occlusive, oxygen-impermeable hydrocolloid dressing compared with petroleum gauze. Infection tendency was not increased under the occlusive dressing.
[Intravenous regional analgesia compared to infiltration analgesia in the reduction of distal forearm fractures].
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[Dysmaturity after uncomplicated pregnancies].
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[Social consequences of waiting lists. A questionnaire study of patients waiting for orthopedic surgery].
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[Bilateral osteochondritis dissecans of the tarsal navicular].
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A quantitative Allen's test.
Allen's test has been performed quantitatively by measuring digital systolic pressure during compression of the radial or ulnar artery at the wrist. The reduction of pressure in normal subjects was less than 25 per cent. Insufficiency of the arterial supply to the hand from the radial artery, the ulnar artery or the palmar arcades can easily be diagnosed from an abnormal reduction in digital systolic pressure during arterial compression.
[Indirect measurement of systolic blood pressure. Strain gauge method compared with auscultation].
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