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Biomedical subjects

S Weinberg

Publications and source records attributed to S Weinberg.

At least 19 recordsLinked to original sources
PubMed2003

Low response rate schools in surveys of adolescent risk taking behaviours: possible biases, possible solutions.

STUDY OBJECTIVE: To examine the potential biases introduced when students in low response rate schools are dropped from classroom based surveys of adolescent risk taking behaviour. DESIGN: Self administered confidential surveys were conducted in classrooms, with follow up visits to each school to survey students absent during the initial survey administration. Data on students in schools that achieved a 70% response rate are compared with data on students in schools that did not achieve this level of response. SETTING: New York City, United States. PARTICIPANTS: 1854 10th graders in 13 public (state supported) high schools. MAIN RESULTS: Students in schools with low response rates resulting from high rates of absenteeism have different demographic characteristics and engage in more risk behaviours than students in schools with low absenteeism and high response rates. Excluding schools with low rates of response can have an effect on estimates of risk behaviour, even after data are weighted for individual absences. The potential for bias is greatest when, in sampling schools, the proportion of schools with low response rates is large, and when such schools represent a large share of the students in the area under study. CONCLUSIONS: Excluding schools with poor response rates from survey samples using a classroom based approach does not improve, and may, under some circumstances, underestimate risky behaviour among adolescent populations.

Absenteeism↗
PubMed2002

Epidemiological and genetic study of 121 cases of oral clefts in Kuwait.

AIM: The aim of the study was to ascertain some epidemiological factors such as sex and consanguinity that may be associated with cleft lip with or without cleft palate (CL +/- CP) in Kuwait as well as to conduct genetic segregation analysis of these families. SETTING AND SAMPLE POPULATION: A total of 113 families ascertained through 121 CL +/- CP and CP surgical probands in Kuwait. The frequencies of cleft types and the epidemiological variables were calculated using SPSS version 5.0 software. Chi-square for goodness-of-fit test was used to test the significance of the associated epidemiological variables to facial clefts. Genetic segregation analysis was performed on 76 families with extended pedigrees and included only those with non-syndromic CL +/- CP (NS CL +/- CP). Major locus segregation analysis was used to fit models to the observed family patterns under Class A regressive models as implemented by REGD routine in S.A.G.E. release 4.0. A test for heterogeneity was also conducted to complete data set in addition to two subsets: Arabs and nomads. RESULTS: Of the 121 patients, 34(28.1%) had CP, 30(24.8%) had CL and 57 (47.1%) had CL + CP. The male to female ratio was 0.89 for CP, 1.14 for CL, 1.35 for CL + CP and 1.2 for all the clefts. The percentage of consanguineous families among those with a positive family history (60%) was not significantly different from that of the general population (54.3%), whereas for all the families with clefts the percent consanguineous was significantly lower (38%). No evidence of heterogeneity in the results between the Arab and nomad subsets was observed. The results for the major locus segregation analysis were inconclusive. CONCLUSION: No definite association was observed between consanguinity and the occurrence of facial clefts in Kuwait. General transmission models in the full data set showed no evidence of heterogeneity in the results between the Arab and nomad subsets.

Adolescent↗
PubMed2001

The use of intra-articular opioids and bupivacaine for analgesia following temporomandibular joint arthroscopy: a prospective, randomized trial.

PURPOSE: This investigation evaluated the efficacy of using intra-articular morphine, bupivacaine, or a combination of both in the management of postarthroscopy temporomandibular joint (TMJ) pain. MATERIALS AND METHODS: Thirty-two consecutive patients with internal derangements of the TMJ and persistent pain underwent TMJ arthroscopy. The patients were randomized equally into 4 groups. Group 1 received a sterile saline solution (control), group 2 received bupivacaine alone, group 3 received only a morphine solution, and group 4 received morphine mixed with bupivacaine. The patients recorded postarthroscopy pain using a visual analog scale (VAS), as well as analgesic consumption for 24 hours. The VAS and analgesic consumption were compared in the 4 groups. RESULTS: Group 3 (bupivacaine alone) consumed, on average, 5.1 fewer analgesic equivalents than did group 1 (control) over the 24-hour period of study (P <.05). Otherwise, there was no significant difference in the number of analgesic equivalents consumed by the 4 groups. Patients treated with bupivacaine alone and those with morphine alone had significantly lower pain scores than the controls. However, there was no significant difference between the pain scores of the morphine and bupivacaine groups at any time. Patients treated with the mixture of morphine and bupivacaine showed no significant difference from controls at any time. CONCLUSIONS: Bupivacaine alone provides a better analgesic effect than morphine alone or the combination of morphine and bupivacaine. Morphine alone has a longer time of onset, with less effect on the pain scores during the 24-hour observation period.

Analgesics, Opioid↗
PubMed2001

A universe with no designer.

Does the universe shows signs of having been designed by a deity like those of traditional monotheistic religions? Physics is in a better position than religion to give a partly satisfying explanation of the world. Recent developments in cosmology help explain why the measured values of the cosmological constant and other physical constants are favorable for the appearance of intelligent life. The presence of evil and misery disturbs those who believe in a benevolent and omnipotent God. It is not necessary to argue that evil in the world proves that the universe is not designed, but only that there are no signs of benevolence that might have shown the hand of a designer.

Extraterrestrial Environment↗
PubMed2001

Developmental screening of children diagnosed with congenital heart defects.

Children with congenital heart disease (CHD) are more likely than normal children to have developmental delays. The development of 64 children with CHD less than 6 years old was screened with the Denver II. Thirty-five of the 64 children had CHD that required surgical or catheter intervention. These 35 children were significantly less likely than other children with CHD to be normal on developmental screening (46% vs 86%, respectively). Thirty-four percent of children with more severe CHD were referred for early intervention. As research shows the efficacy of early intervention, results indicate the need for early developmental evaluation of children with CHD of hemodynamic significance.

Analysis of Variance↗
PubMed2000

Internal derangements of the temporomandibular joint: the role of arthroscopic surgery and arthrocentesis.

Arthroscopic surgery appears to be a safe, minimally invasive and effective method for treating internal derangements of the temporomandibular joint (TMJ), reducing pain and increasing mandibular range of motion for approximately 80% of patients. Although these results are encouraging, they are largely based on retrospective, uncontrolled and short-term studies. The landmark observation that lysis and lavage in only the upper compartment of the TMJ produce successful clinical results without repositioning the disc has prompted clinicians to question the importance of disc position as a significant factor in the etiology of TMJ pain dysfunction. Although there are prospective, controlled, randomized short-term studies indicating that arthrocentesis and arthroscopic surgery have comparable success rates in the management of acute TMJ closed lock, similar long-term studies are lacking. Until they have been done, the roles of arthroscopic surgery and arthrocentesis in the management of TMJ internal derangements remain unclear.

Arthroscopy↗
PubMed1998

A review of common dental treatments during pregnancy: implications for patients and dental personnel.

In general, pregnant females tend to over estimate the risk of teratogenicity in the foetus resulting from medical and dental procedures and/or drugs. This may cause them to avoid necessary treatment, leading to detrimental health effects for both the foetus and themselves. In this review, the concerns of pregnant dental patients and personnel will be discussed, including the perceived risks associated with amalgam restorations, radiation, local anesthetics, nitrous oxide gas, antibiotics and analgesics administered in a dental setting. Pregnant dental personnel have special concerns related to their daily occupational exposure to mercury and nitrous oxide. After assessing the potential risks of undergoing dental treatment during pregnancy, it can be stated that necessary treatment should not be with-held. In addition, dental treatments are best performed in the second trimester for the benefit of the foetus, and optimal comfort for the pregnant woman.

Analgesics↗
PubMed1997

Validation of a scale for network therapy: a technique for systematic use of peer and family support in addition treatment.

Substance abuse treatments are increasingly employing standardized formats. This is especially the case for approaches that utilize an individual psychotherapy format but less so for family-based approaches. Network therapy, an approach that involves family members and peers in the patient's relapse prevention efforts, is theoretically and clinically differentiated in this paper from family systems therapy for addiction. Based on these conceptual differences, a Network Therapy Rating Scale (NTRS) was developed to measure the integrity and differentiability of network therapy from other family-based approaches to addiction treatment. Seven addictions faculty and 10 third- and fourth-year psychiatry residents recently trained in the network approach used the NTRS to rate excerpts of network and family systems therapy sessions. Data revealed the NTRS had high internal consistency reliability when utilized by both groups of raters. In addition, network and nonnetwork subscales within the NTRS rated congruent therapy excerpts significantly higher than noncongruent therapy excerpts, indicating that the NTRS subscales measure what they are designed to measure. Implications for research and training are discussed.

Adult↗
PubMed1996

Analysis of facial and trigeminal nerve function after arthroscopic surgery of the temporomandibular joint.

PURPOSE: This study analyzes facial and trigeminal nerver function after arthroscopic surgery. PATIENTS AND METHODS: Eighty-one consecutive patients (81 joints) who underwent unilateral temporomandibular joint (TMJ) arthroscopic surgery were assessed postoperatively for facial and trigeminal nerve function. RESULTS: Twenty-four of 81 patients (29.6%) had some degree of sensory or motor nerve dysfunction. Two patients (2.5%) showed signs of facial nerve dysfunction, which completely resolved in one patient in 11 weeks, but persisted mildly in the other at the 1-year follow-up examination. CONCLUSIONS: Auriculotemporal syndrome was not detected in any of the 40 patients tested. However, transient numbness over the distribution of the auriculotemporal nerve was present in 19 of 81 patients (23.4%). This numbness persisted for 3 days to 3 months with a mean duration of 14 days. Three of the 81 patients (3.6%) showed signs of inferior alveolar and lingual nerve involvement, which returned to normal in 4 to 12 weeks in all 3 patients.

Adult↗
PubMed1996

Surgical arthroscopy of the temporomandibular joint.

Currently, surgical arthroscopy of the TMJ is primarily confined to the superior joint space, unless there is a perforation in the disc. This is due mainly to the technical limitations imposed in attempting to manipulate a 0.69 mm arthroscope with advanced fibreoptics in the lower joint space. At the present time, operative arthroscopy is "state of the art" treatment for many pathological entities involving the TMJ. Disc entrapment, synovitis, adhesions, chondromalacia, osteoarthritis and lateral capsular impingement can be effectively treated with this technique. While many patients will achieve successful results with this form of therapy, operative arthroscopy is not a panacea, and the need for open arthrotomy must still be reserved for those patients with advanced intracapsular disease. Specifically, anterior disc displacement with reduction, extensive intra-articular fibrosis, failed arthroscopy, avascular necrosis, osteochondritis dissecans, and joint reconstruction often require open arthrotomy for their successful management.

Arthroscopy↗
PubMed1995

Hyperendemic penicillinase-producing Neisseria gonorrhoeae genital infections in an inner city population.

PURPOSE: To determine: 1) the proportion of Neisseria gonorrhoeae caused by penicillinase-producing Neisseria gonorrhoeae (PPNG) in our inner-city population; 2) any difference in the isolation rates of PPNG between adolescents and adults; 3) co-infection rates with Chlamydia trachomatis in this adolescent population; and 4) the appropriateness of current CDC recommendations for initial treatment of patients with suspected gonococcal infection. METHODS: Genital cultures for GC were obtained from 1990 patients seen in the emergency room or primary care clinics. Of these, 285 were adolescents between 12 and 19 years of age. All adolescent patients were tested for chlamydial infection. Comparisons of gonococcal infection rates were made between adults and adolescents and between males and females. The rates of symptomatic versus asymptomatic adolescents were compared. RESULTS: Genital cultures were positive for GC in 13% of the patients tested. Of these, 51% were identified as being caused by PPNG. Among the adolescents, cultures were positive in 25%, and 63% of these were identified as PPNG. The rate of PPNG was significantly higher in adolescents than in adults. The rate of PPNG was highest in adolescent females and lowest in adult males. There was no difference in the rate of PPNG between adolescents and adult males. Of the 71 adolescents with GC, 58% were coinfected with C. trachomatis. Adolescents with PPNG had a higher rate of concomitant infection with C. trachomatis than those with a penicillin-sensitive strain. Adolescents with N. gonorrhoeae were more likely to be infected with PPNG if they had GU symptoms. CONCLUSIONS: Our data supports the most recent CDC recommendations that the initial treatment for suspected N. gonorrhoeae be effective against PPNG. Furthermore, chlamydia screening and treatment is warranted in patients suspected of having an STD.

Adolescent↗