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S Wichmann

Publications and source records attributed to S Wichmann.

6 recordsLinked to original sources

Group JK corynebacteria in skin flora of healthy persons and patients.

The presence of group JK corynebacteria in the skin flora of the axilla and inguinal regions was monitored for several months in three groups comprising 45 oncological patients, 49 dialysis patients and 36 healthy staff members. Oncology patients were colonised significantly more often (51%) than dialysis patients and staff members (33% and 36% respectively). The frequency of isolation did not differ between male patients and staff whereas female patients were colonised significantly more often than female staff members. The inguinal region was colonised more often than the axilla. Oncological patients had the highest proportion of antibiotic resistant group JK corynebacteria strains on their skin and staff members the lowest proportion.

Axilla↗

Isolation of Corynebacterium group JK from clinical specimens with a semiselective medium.

A semiselective medium for the detection of multiresistant lipophilic corynebacteria is described. The medium consisted of tryptose agar, supplemented with Tween 80, lecithin, histidine, glycerol, sodium thiosulfate, fosfomycin, ticarcillin, and 5-fluorocytosine. The medium was tentatively called lecithin-Tween medium (LT medium). It promoted mainly the growth of Corynebacterium group JK, which has recently been identified as a cause of serious infection in immunocompromised patients. The application of LT medium to 6,859 routine clinical specimens increased the percentage of Corynebacterium group JK isolation from 0.1 to 1.0%. Although a total of 72 isolates were found in 65 patients, on the basis of clinical criteria only 2 patients were regarded as having an infection with these bacteria. Consequently, Corynebacterium group JK infection can only be diagnosed through a combination of clinical and microbiological findings. In high-risk areas, however, the use of LT medium for surveillance may facilitate the early detection of these potentially dangerous organisms.

Agar↗

[Septicemia by Corynebacterium group JK in a polytraumatized patient (author's transl)].

A case of septicemia by Corynebacterium group JK is reported in a polytraumatized patient. As the significant feature of this recently isolated group of bacteria is its resistance to almost all antibiotics, therapy of infections is very difficult. Infections can occur in immunocompromised hosts in intensive-care and oncological departments. Both sections should be monitored for these germs, because the JK group can be a part of the normal flora of healthy individuals.

Accidents, Occupational↗