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Biomedical subjects

S Willner

Publications and source records attributed to S Willner.

At least 55 records · Page 3Linked to original sources
PubMed1981

Analysis of operated cases with lumbar renal stenosis.

Twenty-seven patients with spinal stenosis all diagnosed at the surgical exposure and treated with decompression are analysed. The material is divided into three groups according to the preoperative symptoms, those with claudication, those with back and leg pains and those with mixed symptoms. All were myelographed. The radicality of the decompression varied. Excellent and good results were obtained in a total of about 60 per cent. No difference, however, was seen between the three groups. A positive myelography (AP diameter less than 11 mm) was found in all cases with excellent and good results. The postoperative extent of the decompression was studied with a CT-scanner. Here a correlation was found between the range of decompression of the lateral recess and the result of the operation. Also the results seemed to be better with a shorter duration of the symptoms preoperatively.

Constriction, Pathologic↗
PubMed1980

Collagen changes in congenital and idiopathic scoliosis.

Collagen abnormalities in adolescent idiopathic scoliosis have been recorded. In this condition the platelet aggregating power of collagen is decreased and the amount of collagen in suspensions prepared from fascia is increased. We found the same abnormalities in two out of four patients with congenital scoliosis, operated on according to Harrington. In idiopathic as well as in congenital scoliosis the decrease in the platelet aggregating power was more conspicuous in the younger patients.

Adolescent↗
PubMed1980

Collagen-induced platelet aggregation and bleeding time in adolescent idiopathic scoliosis.

Collagen is the main supportive protein of connective tissue. Another of its functions is the initiation of haemostasis by activation of the platelets. It has been suggested that collagen is abnormal in idiopathic scoliosis. The present study lends further support to this view: collagen of fascia specimens from patients with adolescent idiopathic scoliosis was found to aggregate platelets less readily than collagen from non-scoliotic controls and suspensions of fascia patients with adolescent idiopathic scoliosis contained more collagen than those from the controls. The collagen abnormality is probably also reflected in a prolonged bleeding time. The changes in the collagen in patients with scoliosis persist at least for some years after the cessation of growth.

Adolescent↗
PubMed1980

Combined radionuclide phlebography and lung scanning in patients operated on for scoliosis with the Harrington procedure.

Iliac vein thrombosis is an uncommon type of deep vein thrombosis (DVT) that occurs in young patients following surgical procedures for scoliosis. The symptomatology is diffuse and this type of DVT carries a risk for fatal pulmonary embolism as well as the development of a postphlebitic syndrome. Combined radionuclide phlebography and lung scanning were performed in 16 patients operated on for scoliosis with the Harrington procedure. In three patients with diffuse pain in the inguinal region, iliac vein thrombosis was easily visualized in the radionuclide phlebogram and confirmed by conventional phlebography in two cases. Six patients without lung symptoms had perfusion defects typical for pulmonary embolism. It is concluded that radionuclide phlebography can be recommended as a diagnostic procedure for iliac vein thrombosis in patients with diffuse symptoms in the inguinal region or the lower abdomen after scoliosis surgery. Advantages include the ease of performance, good patient acceptance and low radiation dose compared with conventional phlebography. Asymptomatic pulmonary embolism as diagnosed by the perfusion lung scan was an unexpected finding which raised clinical considerations that require further investigations.

Adolescent↗
PubMed1979

Moiré topography--a method for school screening of scoliosis.

The moiré method is tested in school screening of scoliosis. Moiré topography registers a three-dimensional description of the shape of the back. In the straight spine, the moiré shadow pattern is equal on both halves of the back. In structural scoliosis, the moiré pattern differs more with the increasing deformity of the spine. This asymmetry is mainly caused by the rotational component of the scoliosis. These shadow patterns consist of contourlines, which can be compared with those on a relief map. By photographing the moiré shadow lines, the status of the back is documented. In 212 cases, the moiré findings are compared with radiograph observations. A statistically significant correlation is found between the moiré asymmetry (rotational component) and the radiograph findings (lateral deviation according to Cobb). The moiré method seems to fulfil the criteria for a screening method--diagnosis of even minor curves, small risk for false negative findings, simple to handle and can document the back in many children in a short time.

Child↗
PubMed1979

Moiré topography for the diagnosis and documentation of scoliosis.

Moiré topography is a biosteriometric method, which produces a three-dimensional image of the shape of the trunk. In structural scoliosis an asymmetry of the two halves of the back is seen. This method has been studied and the range of the asymmetry of the moire pattern has been compared with clinical observations and X-ray findings in 216 cases with structural scoliosis. A statistically significant correlation between these three ways of describing a structural scoliosis was found. Because of the sensitivity of the moire method an asymmetry of at least one fringe interval could be regarded as a positive result. All the observed asymmetries less than one fringe interval had a lateral deviation of the spine of less than 10 degrees according to Cobb when X-rayed examined. The moire method seems to be very suitable for the screening of structural scoliosis, owing to its ability to detect and document even small deformities by photography and the simplicity of the technique which can be carried out even by staff without medical training.

Adolescent↗
PubMed1978

Progression of a structural scoliosis during treatment with growth hormone. A case report.

A diagnosis of panhypopituitarism was made in an infantile male at the age of 22. Skeletal age was estimated to be 14 years. Thyroxin, corticosteroid and later testosterone was administered. Growth hormone was given initially over a period of ten weeks and later for two and a half years. The standing height increased from 143 to 158.5 cm. During periods of growth induced by growth hormone a progression of a thoracic scoliosis from 15 degrees to 62 degrees was observed. In this case growth hormone or the associated substances seem to be the more probable cause of the progression of scoliosis than growth rate per se.

Adrenal Cortex Hormones↗
PubMed1977

Postoperative kinematics in structural scoliosis.

Three cases with idiopathic, structural scoliosis were examined postoperatively with a roentgen stereophotogrammetric method. Curvatures developed in both the frontal and sagittal planes. Axial rotation also occurred. In addition, residual mobility was demonstrated and quantified one year postoperatively.

Adolescent↗
PubMed1976

Growth hormone and somatomedin A in girls with adolescent idiopathic scoliosis.

Girls with adolescent idiopathic scoliosis are taller than nonscoliotic girls of the same age. This observation may be related to factors regulating longitudinal growth. Plasma growth hormone was determined in a group of scoliotic girls by double antibody radioimmunoassay under the following conditions: 1) Insulin induced hypoglycemia, 2) glucose tolerance test, 3) exercise. Somatomedin A was determined by a method based on the ability of serum to stimulate the incorporation of radioactive sulphate in embryonic chick cartilage. The results were compared with those obtained in a control group of healthy nonscoliotic girls of comparable age. After overnight fasting and after at least one hour's rest the basal growth hormone level was 9.8+/-11.1 (+/-S.D.) ng/ml in the scoliotic girls (n=48) and 2.2+/-1.1 ng/ml in the controls (n=15). This difference is significant. In the hypoglycemia test the peak growth hormone level tended to be higher in the scoliotic girls but the difference is not significant. In the exercise test the maximal value was reached at different times in the two groups: at 20 min after start of the exercise in the scoliotic girls (n=14, 17.3+/-11.8 ng/ml) and at 40 min in the controls (n=9, 16.0+/-6.6 ng/ml). In the glucose tolerance test the growth hormone level was suppressed in both groups but the mean values tended to be higher during the first 120 min in the scoliotic girls. The serum somatomedin levels were higher in the group of scoliotic girls (n=19, 1.13+/-0.17 U/ml) than in the controls (n=14, 0.88+/-0.16 U/ml) and the difference is significant. The results obtained are difficult to interpret but suggest that growth hormone secretion is higher in girls with adolescent idiopathic scoliosis than in healthy girls of comparable age.

Adolescent↗
PubMed1976

Kinematic analysis of posterior spinal fusions in pigs.

Five pigs operated upon by posterior spinal fusion were examined by a roentgen stereophotogrammetric method during provoked motion. The healing process leading to marked rigidity within the spine was followed in two of the pigs. Varying degrees of stability in the fused area were achieved in the five animals. Movements were detected, not only when the fusions were not healed, but also in two cases of incomplete bony union between two operated segments.

Animals↗
PubMed1976

Kinematic analysis of posterolateral fusion in the lumbosacral spine.

Three cases operated upon with posterolateral fusion in the lumbosacral spine have been subjected to a kinematic postoperative analysis with the aid of a roentgen stereophotogrammetric method. The primarily diseased intervals became comparatively rigid in spite of significant residual mobility, in two of the patients, not until 174 days postoperatively. Three levels of operation displayed unrestricted residual mobility.

Adult↗
PubMed1976

Correction with growth following diaphyseal forearm fracture.

In 25 children with fracture of the shafts of the forearm an average angulation deformity of 20 degrees was recorded when the fracture had healed. At follow-up, which took place after the cessation of growth, and angulation deformity was reduced by half; there was, however, a large individual variation. Both severe and less severe deformities were found to be corrected. Correction was more likely in younger children than in older children, though again there were exceptions to this rule. The most common dysfunction recorded was a decreased pronation-supination. This was not very closely correlated with angular deformity.

Adolescent↗
PubMed1975

A study of height, weight and menarche in girls with idiopathic structural scoliosis.

In a series of girls with idiopathic structural scoliosis the height, weight and age at menarche were studied. It was found that the girls were on the average taller than a control population and that except for the most severe cases their height was greater even if the trunk shortening caused by the deformity was not accounted for. The girls with scoliosis were also somewhat leaner. They did not deviate in age at menarche from normal girls in Sweden but there was a positive relationship between the age at diagnosis of the deformity and the age at menarche. When assessed together with previous data on the subject of height in children with scoliosis in Sweden it must be concluded that children with this deformity have a growth pattern which deviates significantly from that of the normal population.

Adolescent↗
PubMed1975

The proportion of legs to trunk in girls with idiopathic structural scoliosis.

The sitting height and its relationship to total height was compared for 164 girls with idiopathic adolescent structural scoliosis and 201 age-matched healthy controls. It was demonstrated that although girls with scoliosis were taller than controls the relationship between trunk and legs was undisturbed.

Adolescent↗
PubMed1975

Difference in leg length in children with coxa plana during and after treatment using unilateral unloading.

In unilateral coxa plana a shortening of the affected leg can often be found. This shortening affects not only the caput-collum part of the femur but also the other parts of the femur and the tibia. In this study, however, the immobilization of the affected leg seemed to be the main reason for the observed difference in the leg length. Children who had not unloaded their affected leg as carefully as they should proved to have a smaller difference in leg length than those who had unloaded their affected leg according to the instructions. On the other hand compensatory growth of the affected leg was found when both legs were again taking weight. The difference in the leg length was significantly reduced one year after the completion of the treatment.

Child↗