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Biomedical subjects

S Winsten

Publications and source records attributed to S Winsten.

At least 19 recordsLinked to original sources

Immunoglobulin G (IgG) levels in breast tumor cytosols.

Immunonephelometer investigation of specific proteins revealed a difference in levels of immunoglobulin G (IgG) found in the cytosol of estrogen receptor (ER) rich and estrogen receptor poor tumor tissue. Cytosols from estrogen receptor poor tumors had a significantly higher level of IgG than those from estrogen receptor rich tissues. The relationship between progesterone receptor levels and IgG was not as significant as that observed between ER levels and IgG. Other specific proteins did not correlate with either estrogen receptor levels or progesterone levels.

Breast Neoplasms↗

Double light-chain disease: a case report.

A patient with massive proteinuria was discovered to have double light-chain disease. Immunological studies demonstrated monoclonal light chains of both the lambda and kappa type in urine. The light chains were separate and distinct and were not found to be a part of any of the whole molecule immunoglobulins such as IgG, IgM, IgA, IgD, or IgE. Uniqueness of the proteins was confirmed by column chromatography. Clinical studies showed that the patient had multiple myeloma.

Aged↗