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Biomedical subjects

S Witters

Publications and source records attributed to S Witters.

5 recordsLinked to original sources

Primary neoplasm of the ureter: a review of twenty-eight cases.

Twenty-eight patients with primary ureteral neoplasms of which 7 of a benign type were reviewed retrospectively. Sixteen of these patients underwent segmental resection, with a 2-year survival of 81% and with no ureteral recurrence. Eleven other patients underwent a complete nephroureterectomy with bladder cuff excision with a subsequent 2-year survival of 63.6%. We believe that segmental resection is indicated in all low-grade and low-stage lesions and with a small chance of recurrence.

Carcinoma, Transitional Cell↗

Bladder exstrophy complicated by adenocarcinoma.

A case of untreated exstrophy in a 72-year-old patient complicated by malignant degeneration is reported. Morphological, histochemical and immunohistochemical examination revealed an adenocarcinoma resembling a colorectal carcinoma.

Adenocarcinoma↗

Iatrogenic ureteral injury: aggressive or conservative treatment.

Many different approaches are advocated for management of iatrogenic (operative) ureteric injury. We herein report our experience with 28 ureteral injuries in 26 patients. In six patients, seven injuries were recognized at the time of the initial operation; four end-to-end anastomoses and three ureteroneocystostomies were successfully performed. In 20 patients the diagnosis of injury was delayed. In 14 of them a ureteroneocystostomy with or without Boari bladder flap was performed. The other six patients were first treated by percutaneous nephrostomy, which was successful in only two cases. The other four needed subsequent operative management. The main point that has emerged from our review is that early definitive operative repair is both feasible and preferable.

Adult↗

Papillary adenocarcinoma of the prostatic urethra.

Three cases of papillary carcinoma of the prostate (also called endometrial adenocarcinoma of the prostate; endometrioid carcinoma) were studied for prostate-specific antigen in order to determine their origin and histogenesis. All 3 cases were prostate-specific antigen positive. Two patients were treated with hormonal therapy, 1 with radiotherapy.

Adenocarcinoma↗

Malignant priapism.

Priapism, the persistent painful erection unrelated to sexual stimuli, is called malignant whenever the priapism is due to metastases. A new case of malignant priapism, secondary to metastases of prostatic carcinoma is presented. As usual, survival was poor--our patient died 3 months after diagnosis was established.

Acid Phosphatase↗