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S Y Fu

Publications and source records attributed to S Y Fu.

6 recordsLinked to original sources

Observation on the effect of sodium nitroprusside and dopamine on acute myocardial infarction during hospitalization.

With improvements in cardiac monitoring systems and the effective treatment of arrhythmias, the case-fatality rate of acute myocardial infarction (AMI) has been declining gradually since 1972. But since 1977, despite the great efforts of medical workers in many countries, the lowest case-fatality rate of AMI has still been about 10%. Over many years, our institute has carried out research aimed at improving the treatment of AMI. However, in our institute the case-fatality rate has fluctuated between 15 and 20% in recent years. From March 1986 to January 1987 we adopted a sodium nitroprusside and dopamine intravenous drip in the treatment of 92 cases of AMI and achieved a hospitalization period AMI case-fatality rate of less than 5% (2 patients died). The treatment methods and relevant materials are reported here.

Adult

Correlation study of left atrial pressure and pulmonary rheogram.

In order to observe correlations between LAP and PRG data, we placed small inflated balloons in the left atria of dogs to change LAP. We found good correlations between LAP and Q-6 interval (r = 0.88, P less than 0.001), b-s interval (r = -0.78, P less than 0.001), Hs (r = -0.59, P less than 0.001), Hs X b-s interval (r = -0.65, P less than 0.001), and HD/Hs (r = 0.50, P less than 0.001). The mechanisms of change of these parameters were investigated and corresponding regression equations derived. The authors point out that D wave enlargement and HD/Hs increase are determinant indices of LAP elevation and may be used to estimate LAP and to differentiate LAP elevation from simple pulmonary hypertension. Therefore, we conclude that PRG may reflect changes of pressure or volume in the pulmonary vein and thus provide a noninvasive method of monitoring cardiac preload and the pulmonary cycle. In addition, this research may provide the experimental basis for employing PRG in the study of such pathological processes as mitral valve lesion, left heart failure, etc.

Animals