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Biomedical subjects

S Y Horng

Publications and source records attributed to S Y Horng.

6 recordsLinked to original sources
PubMed2000

Intralesional corticosteroid therapy in proliferating head and neck hemangiomas: a review of 155 cases.

PURPOSE: The purpose of this paper is to review the effect of intralesional corticosteroid therapy in the treatment of 155 head and neck hemangiomas. METHODS: In the past 10 years, we have treated 155 proliferating head and neck hemangiomas with intralesional corticosteroid injections. Three to 6 injections of triamcinolone acetonide (10 mg/mL) in monthly intervals were given. Using slides and chart review, the results were assessed 1 month after completion of the treatment. RESULTS: Eighty-five percent of the lesions showed greater than 50% reduction in volume. Varied treatment response was noted in different classes of hemangioma. Eighty percent of the superficial, 75% of the deep, and 60% of the combined hemangiomas show more than 50% reduction in volume. Further growth was not found after treatment. The postinjection complication rate was 6.4% in this series. There were 2 patients with cushingoid appearance, 5 with cutaneous atrophy, and 3 suffered from anaphylactic shock. We found that lesions showing less than 50% reduction in volume were located mostly in the perioral area. CONCLUSIONS: Intralesional corticosteroid injections are safe and effective in arresting hemangioma proliferation. Superficial hemangiomas yield the best results.

Adrenal Cortex Hormones↗
PubMed1996

Treatment of high-flow vascular malformations in the head and neck with arterial ligation followed by sclerotherapy.

The traditional treatment of high-flow vascular malformations consists of selective embolization, surgical removal, or a combination of both. Recurrence of the lesion and bleeding control are still the main problems, and the result of treatment is sometimes disappointing. We suggest treatment of these lesions with surgical ligation of the distal major feeding arteries followed by intravascular injection of a sclerosing agent (3% tetradecyl sulfate), and surgical excision and reconstruction when indicated. We have found this to be an effective treatment regimen. We present 14 cases of high-flow vascular malformations of the head and neck area treated with this approach, of which 4 cases developed skin necrosis. Three of these 4 cases of skin necrosis were later treated with skin grafting and, in 1 case, an upper arm skin tube flap was used for nasal tip reconstruction. Three cases underwent delayed reconstruction using tissue expanders. From a symptomatic and aesthetic point of view, preliminary satisfactory results were obtained. We feel that this approach is a good option for treating difficult, high-flow vascular malformations.

Adolescent↗
PubMed1994

A new method of microskin mincing.

Microskin grafting has been used successfully for major burns when donor skin areas are inadequate to cover the skin defect. The microskin may be made by repeated cutting with scissors or by a specially designed machine. However microskin grafting is still not popular due to the difficulty of the mincing process, which may take hours to do. An easy and quick method of skin mincing using the Tanner-Vandeput Mesh Dermatome has been developed. The mincing process may be done in just a few minutes instead of hours. The skin pieces made with this technique are all of a uniform square shape and size (1.2 mm x 1.2 mm). Microskin grafting using the mincing technique has been carried out on 10 thighs of five patients with a fixed patch size (1.2 mm x 1.2 mm); an expansion ratio of 1:10 is used to ensure that the average interpatch distance would be within 5 mm for a better and quicker healing. All areas healed within 6 weeks without any secondary skin grafting. The resulting 'cobblestone' appearance of the healed skin is not good looking but there is no excess scar formation. The scar is soft and can be pinched up easily. This is an easy way of microskin mincing, it is quick and can be done in any clinic without specially trained personnel or the need to buy a new instrument.

Burns↗
PubMed1993

Reversed cephalic vein: a lifeboat in head and neck free-flap reconstruction.

Free flaps always followed surgical resection in head and neck cancer patients as a means of reconstruction. Problems may be encountered in recurrent patients who have received postoperative cervical irradiation, since finding a good, healthy vein for microanastomosis is sometimes difficult. The internal jugular vein, with or without vein grafting, as the recipient vessel may solve the problem. However, we encountered two patients in whom the internal jugular vein was very fibrotic as a result of irradiation. A long vein graft to the nonirradiated, healthy area was the only choice in this condition. A new method in which a reversed cephalic vein is used as the recipient vessel was designed. It seems that the reversed cephalic vein can play the role of lifeboat as recipient vein and solve the most difficult problem encountered in head and neck free-flap surgery.

Fibrosis↗