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S Zółtowski

Publications and source records attributed to S Zółtowski.

7 recordsLinked to original sources
PubMed2003

Leptin, neuropeptide Y, beta-endorphin, gonadotropin, and estradiol levels in girls before menarche.

More than two decades of clinical studies have provided us with the opportunity to develop and implement criteria that distinguish three phases during pre-menarche, paralleling rising levels of estrogens, namely 'pre-estrogenization', 'onset of estrogenization' and 'full estrogenization'. The aim of this study was to examine the relationships between somatic features and levels of leptin, neuropeptide Y (NPY), beta-endorphin, gonadotropin and estradiol in pubertal girls before menarche. Weight, height, body mass index (BMI), tertiary sex features, estrogen-related changes in hymen, fat and lean body mass were studied on a quarterly basis in 45 girls. At the same time, ovarian and uterine dimensions were established sonographically and serum was obtained for the determination of leptin, NPY, beta-endorphin, gonadotropin, and estradiol levels. Onset of estrogenization in girls was marked by weight loss, followed by an increase in total, fat and lean body mass, and pubertal acceleration of growth. At the time of full estrogenization, lower NPY and beta-endorphin levels were observed, accompanied by an increase in gonadotropin secretion. Changes in leptin levels are consistent with a role of this hormone in metabolic signaling.

Body Composition↗
PubMed2001

[Growth hormone, insulin, IGF-1 and estradiol levels during maturation of internal sex organs before and at menarche].

INTRODUCTION: The growth hormone (GH) is the main activator of growth, exerting its biological effects through IGF-1 and IGF-2 growth factors. Secretion of GH is partly controlled by steroid sex hormones. MATERIAL AND METHODS: Body mass, height, BMI, and body composition were recorded every three months in 45 healthy girls 8 years of age. Tertiary sex features according to Tanner were determined. Transabdominal ultrasound of the uterus and ovaries was done. GH, insulin, and IGF-1 levels in serum were measured radioimmunologically with commercial test kits. E2 levels were determined with an immunoenzymatic method. RESULTS: GH levels increased until stage M3 of breast maturation and gradually decreased during stage M4 (12 girls with menarche). IGF-1 and insulin levels continued to increase until stage M4. Uterine and ovarian dimensions correlated with levels of hormones studied. CONCLUSION: High levels of GH and IGF-1 during the early and central stages of puberty seem to affect the maturation of internal sex organs.

Adolescent↗
PubMed1999

[Laparoscopy in the diagnosis and treatment of pathology of sexual organs in girls].

DESIGN: The aim of our study was a clinical analysis of laparoscopies in girls which were performed in the Clinic of Gynaecological Surgery. MATERIAL AND METHODS: Laparoscopic procedures were carried out between 1996-1998. Patients were divided in to three groups: aged under 15, between 15-19 and over 19. 44% of patients from the youngest group had laparotomy. 43.8% of laparoscopic interventions were in aged group 20-24. CONCLUSION: Laparoscopy is very good diagnostic method in gynaecological diseases. It gave enabled operative treatment in 40-43.8% girls.

Adolescent↗
PubMed1993

[The course of sexual development in girls with diabetes type I in view of ultrasonographic examinations].

The gynecologic a ultrasonographic examinations in 34 insulin--dependent diabetic girls aged from 1-9 y, were performed. Diabetes duration oscillated between 1-9 y. The obtained results showed that the dynamics of sexual maturation of this girls was independent of theirs calendar age, but was conditioned by the time of obtained sexual development. The right metabolic balance of diabetes stipulates regular course of sexual maturation.

Adolescent↗
PubMed1993

[Ultrasonography, laparoscopy, neoplastic markers--new possibilities of conservative operative treatment for ovarian neoplasms in girls and young women].

The knowledge of ovarian physiopathology and the employing of modern diagnostic methods (ultrasonography, laparoscopy) allow to avoid to operate patients with functional cysts. Girls and young women should be evaluated individually for ovarian surgical procedures. The operative treatment should be so conservative as possible employing all diagnostic and monitoring methods including specific markers assays.

Adolescent↗