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Biomedical subjects

Sabrina Oesterle

Publications and source records attributed to Sabrina Oesterle.

3 recordsLinked to original sources
PubMed2006

Linking substance use and problem behavior across three generations.

This study examined patterns of between-generation continuity in substance use from generation 1 (G1) parents to generation 2 (G2) adolescents and from G2 adult substance use and G1 substance use to generation 3 (G3) problem behavior in childhood. Structural equation modeling of prospective, longitudinal data from 808 participants, their parents, and their children showed low levels of G1 to G2 cross-generational continuity in the general tendency to use drugs. This effect was fully mediated by G2 early adolescent behavior problems. Drug-specific residual effects were observed across generations for cigarette smoking. Once established in adolescence, substance use in G2 showed stability over time. G2 substance use at age 27 significantly predicted G3 problem behavior. G1 substance use also was related to G3 problem behavior indirectly. These findings highlight the importance of interrupting intergenerational cycles of substance use and problem behavior.

Adolescent↗
PubMed2004

Adolescent heavy episodic drinking trajectories and health in young adulthood.

OBJECTIVE: This study examined the association of trajectories of heavy episodic drinking (at least five alcoholic drinks on one occasion) during adolescence with health status and practices at age 24. METHOD: Semiparametric group-based modeling and logistic regressions were used to analyze data from a longitudinal panel of 808 youths interviewed between 10 and 24 years of age. RESULTS: Four distinct trajectories of adolescent heavy episodic drinking were identified: nonheavy drinkers, late onsetters, escalators and chronic heavy drinkers. Overall, young adults who did not engage in heavy episodic drinking during adolescence had the lowest occurrence of health problems and were most likely to engage in safe health behaviors at age 24. Chronic and late-onset heavy episodic drinking during adolescence had negative effects on health status and practices at age 24. Adolescent chronic heavy drinkers were more likely to be overweight or obese and to have high blood pressure at age 24 than those who did not drink heavily in adolescence. Late-onset heavy drinkers were less likely to engage in safe driving practices at age 24 and were more likely to have been ill in the past year than adolescents who did not drink heavily. These health disparities remained even after current frequency of heavy episodic drinking at age 24, other adolescent drug use, ethnicity, gender and family poverty were controlled. CONCLUSIONS: Heavy episodic alcohol use during adolescence has long-term, negative health consequences. Distinct patterns of adolescent heavy drinking affect health status and practices in young adulthood differently.

Adolescent↗