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Biomedical subjects

Sadek Cheaib

Publications and source records attributed to Sadek Cheaib.

5 recordsLinked to original sources

[Acute cytomegalovirus (CMV) recto-colitis mimicking rectal carcinoma without apparent cause of immunodeficiency].

Cytomegalovirus (CMV) infection of the gastrointestinal tract occurs mainly in immunosuppressed patients. We report here the case of a 76-Year-old woman, without obvious cause of immunosuppression, who developed severe proctitis. The clinical course was favourable with ganciclovir therapy. In the absence of controlled data in the field of CMV intestinal infections in immunocompetents, we discuss the potential benefit of an antiviral therapy in those patients who do not recover rapidly and spontaneously.

Acute Disease↗

[Regression of hepatocellular carcinoma under Tamoxifen: report of one case and review of the literature].

Hepatocellular carcinoma is a malignant tumor with a poor prognosis, particularly when it is unresectable. The results of tamoxifen treatment in hepatocellular carcinoma have been disappointing and randomized studies have shown conflicting results. We report the case of a 72-yr-old-man with histologically confirmed hepatocellular carcinoma on a normal liver, that regressed with tamoxifen treatment. Regression was confirmed by normalization of serum alpha-fetoprotein levels and a significant decrease in radiological lesions by 66%. The patient was alive in excellent clinical condition more than 30 months after the initial diagnosis.

Aged↗

[Single filiform polyp revealed by severe haemorrhage in a patient with normal colon. Report of a case and review of the literature].

Filiform polyposis or giant inflammatory polyp is an uncommon benign lesion that has principally been reported in patients with evidence of inflammatory bowel disease, Crohn's disease or ulcerative colitis. It appears to be a sequella of diffuse mucosal inflammation. More rarely, PF found in association with colonic non specific inflammation. PF has rarely been reported in patients without previous colonic disease. We report the case of a 60-year-old woman without history of colonic disease who presented a PF revealed by hematochesia.

Colonic Polyps↗