Biomedical subjects

Sadrettin Pençe

Publications and source records attributed to Sadrettin Pençe.

4 recordsLinked to original sources

PubMed2003

The alterations in adenosine nucleotides and lactic acid levels in striated muscles following death with cervical dislocation or electric shock.

In this study, changes in adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP) and lactic acid levels in masseter, triceps, and quadriceps muscles obtained from right and left sides of Spraque-Dawley rats following two different types of death were investigated. The samples were taken immediately and 120 minutes after death occurred either by cervical dislocation or electric shock. ATP concentrations in the muscles of masseter, triceps, and quadriceps were lower in samples obtained 120 minutes after death than that of samples obtained immediately after death. ADP, AMP, and lactic acid concentrations in these muscles were higher in samples obtained 120 minutes after death than those obtained immediately after death. A positive linear correlation was determined between ATP and ADP concentrations in quadriceps muscles of the rats killed with cervical dislocation and in masseter muscles of the rats killed with electric shock. When the rats killed with cervical dislocation and with electric shock were compared, ADP, AMP, and lactic acid concentrations were lower in the former than in the latter for both times (immediately and 120 minutes after death occurred). In the case of electric shock, ATP is consumed faster because of immediate contractions during death, resulting in a faster rigor mortis. This finding was confirmed with higher lactic acid levels in muscles of the rats killed with electric shock than the other group. In the cervical dislocation and electric shock group rats, ATP decreased in different levels in the three different muscle types mentioned above, being much decline in masseter in cervical dislocation and in quadriceps in electric shock group. This may be caused by low mass and less glycogen storage of masseter and by near localisation of electrode to quadriceps. One can conclude that the occurrence of rigor mortis is closely related to the mode of death.

Adenine Nucleotides↗

PubMed2003

The alterations in adenosine nucleotides and lactic acid in striated muscles of rats during Rigor mortis following death with drowning or cervical dislocation.

In this study, adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP) and lactic acid in the muscles of masseter, triceps, and quadriceps obtained from right and left sides of Spraque-Dawley rats following death were investigated. The samples were taken immediately and 120 minutes after death occurred. The rats were killed either by cervical dislocation or drowning. ATP concentrations in the muscles of masseter, triceps, and quadriceps were lower in samples obtained 120 minutes after death than in those obtained immediately after death. ADP, AMP, and lactic acid concentrations in these muscles were higher in samples obtained 120 minutes after death than those obtained immediately after death. A positive linear correlation was determined between ATP and ADP concentrations in quadriceps muscles of the rats killed with cervical dislocation and in triceps muscles of the rats killed with drowning. When rats killed with cervical dislocation and with drowning were compared, ADP, AMP, and lactic acid concentrations were lower in the former than in the latter for both times (immediately and 120 minutes after death occurred). In the case of drowning, ATP is consumed faster because of hard exercise or severe physical activity, resulting in a faster rigor mortis. Higher lactic acid levels were determined in muscles of the rats killed with drowning than the other group. In the control and electric shock rats, ATP decreased in different levels in the three different muscle types mentioned above in control group, being much decline in masseter and then in quadriceps. This may be caused by lower mass and less glycogen storage of masseter. No different ATP levels were measured in drowning group with respect to the muscle type possibly because of the severe activity of triceps and quadriceps and because of smaller mass of masseter. One can conclude that the occurrence of rigor mortis is closely related to the mode of death.

Adenine Nucleotides↗

PubMed2002

Paw preference in rats.

We applied a food-reaching test to investigate paw preference in 114 Spraque-Dawley rats and to determine whether a correlation exists between paw preference and gender. We found that 70.2% of rats were right-pawed, 19.3% were left-pawed, and 11.9% were ambidextrous. No significant difference was found between right-pawed, left-pawed, and ambidextrous male and female rats. The results indicate that the distribution of paw preference in rats is similar to that of other animals and to human handedness.

Animals↗

PubMed2002

Serum lipid and lipoproteins in gallstone patients.

Serum lipid and lipoprotein concentrations were determined in a group of thirty two gallstone patients and compared to the values obtained in thirty two healthy control subjects. The serum levels of high density lipoprotein cholesterol and lipoprotein(a) in gallstone patients were found to be lower than that of the control group. Total cholesterol, triglyceride, low density lipoprotein cholesterol, apoprotein-A and apoprotein-B concentrations were observed to be higher in gallstone patients than the controls. The differences in triglyceride and low density lipoprotein cholesterol concentration were statistically significant. However, there was no significant difference in high density lipoprotein cholesterol, lipoprotein(a), apoprotein-A, apoprotein-B, and total cholesterol concentrations between groups. It is concluded that gallstone formation may be related to a disturbance in lipid and lipoprotein metabolism.

Adult↗