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Biomedical subjects

Salih Cesur

Publications and source records attributed to Salih Cesur.

28 records · Page 2Linked to original sources

[Hepatitis A and hepatitis E seroprevalence in adults in the Ankara area].

In this study, between the period of September 2000 to July 2001, hepatitis A virus (HAV) IgG antibodies and hepatitis E virus (HEV) total (IgG + IgM) antibodies have been searched by using commercially provided enzyme immunoassay kits (Axsym, Abbott USA), in 1046 adults aged between 15-75 years old (mean age: 32.3 years), who were admitted to the outpatient clinics of Internal Medicine and Infectious Diseases Department of Ankara University Medical School, with no acute hepatitis signs and symptoms. As a result, anti-HAV and anti-HEV seropositivities were detected in 914 (87.4%) and 40 (3.8%) subjects, respectively. The seropositivity rate for anti-HAV was 72.7% at the ages of 15-30 years, while anti-HEV was negative in this age group. Anti-HAV and anti-HEV seropositivity rates were found to be the highest between the ages of 30-60 years.

Adolescent↗

[Case report: evaluation of two cases of tuberculoma incident to tuberculosis meningitis].

Intracranial tuberculoma is one of the most serious complications of tuberculous meningitis. In this report, two patients who develop intracranial tuberculoma as a complication of tuberculous meningitis have been presented. The first patient was a 35 years old male patient who were still been in therapy for cavitary tuberculosis. The other one was 42 years old male patient and have had treated for subdural empyema two years ago. There was no positivity in both of the cerebrospinal fluid (CSF) specimens of the patients by Gram and Erlich Ziehl Neelsen stained preparations, while the CSF sample of the first case yielded Mycobacterium tuberculosis in culture. The tuberculoma diagnosis of these patients managed by the help of computerized tomography (CT) and nuclear magnetic resonance imaging (NMR) methods. As a result, it was thought that CT and NMR techniques have a great role in the diagnosis and management of complications in tuberculous meningitis patients.

Adult↗

[Case report: brucellosis complicated by epididymo-orchitis and paravertebral abscess].

Brucellosis which is a zoonotic infection involving many systems, is widespread in Turkey. Although muscular and skeletal system involvements are common, genitourinary system complications (epididymo-orchitis) are observed rarely. Brucellosis accompanied by abscess formation in the vertebra is generally seen in the elderly and patients with chronic diseases, while epididymo-orchitis in young patients. However, it is very unusual to detect these two complications together. In this report, a case of 42 years old male patient with epididymo-orchitis and paravertebral abscess due to brucellosis, has been presented.

Abscess↗

[Case report: a brain hydatid cyst].

Hydatid cyst is a zoonotic infection caused by larval stage of Echinococcosis granulosus. Although any organ may be involved, bone, brain and heart involvements are uncommon. The brain involvement rate varies from 1% to 3% in hydatid disease. In this report, a 42 years old female patient has been presented in whom brain hydatic cyst was diagnosed by radiological and histopathological findings.

Adult↗

[Case report: psoas abscess due to brucellosis].

Skeletal system involvement is relatively a common complication of human brucellosis. However, muscular involvement is less frequent, and particularly psoas abscess is always secondary to spondylitis. In this case report, psoas abscess formation in a 70 years old female brucellosis patient complicated with spondylitis on vertebral corpus, has been presented.

Aged↗

[Determination of nasal carriage rates of methicillin resistant Staphylococcus aureus in hospital personnel and in the community].

In this study, methicillin resistant Staphylococcus aureus (MRSA) nasal carriage rates in hospital staff and community were investigated. The study included 500 hospital personnel and 500 outpatients in Ibni Sina Hospital and Cebeci Hospital of Ankara University School of Medicine between January 1999-March 2001. Outpatients were assigned into the control group and hospital staff into the study group. MRSA nasal carriage rates of hospital staff and control group were found to be 6% and 2.6%, respectively, and the difference between these groups were statistically significant (p < 0.001). There was no significant difference in the nasal carriage rates among the different members of the hospital personnel such as physicians, nurses and auxilliary staff (p > 0.05), however the rates were higher especially in the personnel who were mainly working in the surgical wards and operating theaters.

Carrier State↗

[Topical antibiotics and clinical use].

Topical antibiotics offer a useful alternative to oral and parenteral agents in certain conditions and have some advantages such as easy to use, lower side effects, higher drug concentrations in the infected area, lower risk of developing bacterial resistance and being economical. The goals of topical antimicrobial therapy are to control microbial colonization, thus preventing development of invasive infections, prophylaxis and treatment of wound infections, pyodermas, burn infections and acne vulgaris, and eradication of Staphylococcus aureus nasal carriage. Topical antibiotics of choice include bacitracin, neomycin, polymyxin B, mupirocin, nitrofurazone and fusidic acid. In this review article, the characteristics and clinical uses of topical antimicrobials have been summarized.

Anti-Bacterial Agents↗

The significance of cryoglobulinemia in patients with chronic hepatitis B and C virus infection.

BACKGROUND/AIMS: Mixed cryoglobulinemia is frequently seen in liver disease and chronic viral hepatitis. The aim of this study is to determine the prevalence and clinical findings of cryoglobulins in patients with chronic hepatitis B and chronic hepatitis C. METHODOLOGY: Cryoglobulins were precipitated from serum stored for up to 7 days. The precipitates were washed five times at 4 degrees C with 0.15 mol/L NaCl and total protein concentration was measured by reading absorbance at 280 nm. RESULTS: The prevalence of cryoglobulinemia was higher in patients with hepatitis C than in patients with hepatitis B (16.6% and 4.6% respectively). Patients with cryoglobulinemia had several symptoms such as arthralgia and weakness. CONCLUSIONS: Cryoglobulin-positive chronic hepatitis B and C patients should be investigated in terms of cryoglobulinemia symptoms and complications.

Adult↗

[Comparison of auramine-rhodamine and Erlich-Ziehl-Neelsen staining methods for the diagnosis of tuberculosis].

The aim of this study was to compare auramin-rhodamine (A-R) and Erlich-Ziehl-Neelsen (EZN) staining techniques for the diagnosis of tuberculosis. Of 311 sputum samples collected from active pulmonary tuberculosis patients and tuberculosis-suspected patients, 103 (33%) were found culture positive. In the direct microscopic examination of EZN stained smears, 86.4% (89/103) of culture positive samples, and 3.8% (8/208) of culture negative samples yielded asido-resistant bacteria, while these rates were 74.8% (77/103) and 11.5% (24/208) for A-R staining method. When culture was accepted as reference method, the specificity and sensitivity of the staining techniques were found as 88.5% and 74.8% for A-R, and 96.2% and 86.4% for EZN, respectively. As a result, it was concluded that, the use of A-R staining alone, could not be an alternative method to EZN staining.

Benzophenoneidum↗

[Prevalence of extrahepatic illnesses in patients with chronic hepatitis b and hepatitis c: retrospective study of 435 patients].

Chronic infections that caused by hepatitis B and C viruses, are important all of the world as a public health problem. Despite intensive control measurements, the incidences of chronic hepatitis B and C virus infections in our country are estimated as 5-7% and 3%, respectively. There are accumulating data of especially autoimmune mediated extrahepatic manifestations of hepatitis B and C virus infections, such as Diabetes Mellitus (DM), Behçet's Disease (BD), hypo- or hyper-thyroiditis and autoimmune diseases. The aim of this study was the retrospective evaluation of 400 chronic B hepatitis (CBH) and 35 C hepatitis (CCH) patients by means of the presence of extrahepatic manifestations. As a result, the positivity rates of extrahepatic manifestations detected in CBH and CCH patients were as follows respectively; 1.5% and 8.5% for DM, 1.5% and 5.7% for hypothyroiditis, 0.75% and 2.8% for hyperthyroiditis, 2% and 20% for nodular goitre, 0.25% and 5.7% for BD, 1% and 0% for systemic lupus, 1% and 5.7% for Rheumatoid Arthritis (RA), and 22% and 11.4% for iron deficiency anemia. DM, thyroid diseases and RA were the most common extrahepatic manifestations detected in both of the patient groups, while the rates of DM, BD and nodular goitre were found higher in CCH patients than CBH patients (p < 0.05). As a result, the extrahepatic manifestations should be carefully followed in patients with chronic hepatitis B and C infections, for an early diagnosis and appropriate treatment.

Adult↗