Biomedical subjects

Samuel Levinger

Publications and source records attributed to Samuel Levinger.

9 recordsLinked to original sources

PubMed2006

Laser in situ keratomileusis in myopic patients with congenital nystagmus.

PURPOSE: To evaluate the results of laser in situ keratomileusis (LASIK) and IntraLASIK in the treatment of myopic patients with nystagmus. METHODS: Eight patients with congenital nystagmus (16 eyes), aged 23 to 49 years, had LASIK surgery. Corneal flaps were created using the Bausch & Lomb Hansatome microkeratome or the IntraLase femtosecond laser. The ablations were performed with the Bausch & Lomb excimer laser with an active tracking system. In some patients, the eyes were fixated with forceps or a fixation ring during laser ablation. RESULTS: The refractive errors were corrected in all cases. There was no decentration or loss of best corrected visual acuity greater than 1 line. In 56% of the eyes, the postoperative uncorrected visual acuity was better than the best spectacle-corrected visual acuity (BSCVA). The BSCVA improved in 62.5% of the eyes. The overall visual performance improved in all patients. One patient who did not drive before surgery became eligible for a driver's license after surgery. CONCLUSIONS: Selected patients with myopia and congenital nystagmus may benefit from laser refractive surgery. Laser refractive surgery may be safely and accurately performed using the Hansatome microkeratome or the IntraLase femtosecond laser and an active tracking system with or without mechanical fixation. The BSCVA may improve in certain patients postoperatively.

Adult↗

PubMed2006

Intacs adjustment surgery for keratoconus.

PURPOSE: To describe the visual outcome of keratoconic eyes managed with Intacs (Addition Technology, Inc.) that required additional Intacs surgery (defined as any combination of removal, exchange, addition, or shifting of an Intacs segment). SETTING: Private refractive surgery center, Jerusalem, Israel. METHODS: This retrospective noncomparative interventional consecutive small case series studied all eyes of a cohort of 58 keratoconic eyes managed with Intacs that had additional Intacs surgery. The uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity, manifest refraction, videokeratography, and patient questionnaires on visual function were assessed. These outcome measures were compared before Intacs implantation, before Intacs adjustment, and 1 year after the final Intacs adjustment. Eyes having any intervention other than Intacs surgery were excluded. RESULTS: Of 58 keratoconic eyes managed with Intacs, 7 had additional Intacs surgery. After the initial Intacs surgery, 6 of these eyes had UCVA < or =20/100 and 1 had UCVA of 20/50. After the final Intacs adjustment, 3 eyes achieved UCVA > or =20/40, 5 achieved UCVA > or =20/70, and 2 remained <20/200. The indications for Intacs adjustments were increased astigmatism in 4 eyes, induced hyperopia (overcorrection) in 3, and undercorrection in 1. One eye had both surgically induced astigmatism and hyperopia. Induced astigmatism and hyperopia were most often managed by removing the superior segment. The undercorrected eye, having initially received a single inferior segment, was treated by implanting a superior segment. CONCLUSIONS: Approximately 10% of keratoconic eyes managed with Intacs may require Intacs adjustment surgery, which often has a good outcome.

Adult↗

PubMed2006

[Wavefront-guided lasek after intacs in eyes with stable keratoconus].

BACKGROUND: Keratoconus is a non-inflammatory, progressive thinning disorder of the cornea, resulting in a typical protrusion and in refractive errors and low visual acuity. Many of the patients with stable keratoconus encounter difficulties wearing glasses or contact lenses. PURPOSE: To evaluate the results of wave-front guided laser assisted subepithelial keratectomy (LASEK) for the correction of residual spherical and spherocylindrical myopia after INTACS insertion in patients with stable keratoconus. METHODS: Four eyes of keratoconus patents were treated with Zyoptix wavefront-guided LASEK for correction of residual myopia and astigmatism after insertion of INTACS. The refraction after insertion of INTACS was stable at least six months before the Zyoptix-LASEK. The mean pre-INTACS refraction was myopia of -2.37 D (range 0 to - 5.00 D) and astigmatism of -3.93 D (range -1.00 to -7.5 D). The mean refraction prior to Zyoptix-LASEK was myopia of -0.2 D and astigmatism of -2.71 D. The mean follow-up period after the Zyoptix LASEK was 8 months. RESULTS: Initially, prior to both surgeries, the mean uncorrected visual acuity was 6/240 (range count-fingers to 6/60) and at the final postoperative visit 6/12 (range 6/10 to 6/ 18). The preoperative mean best spectacle corrected visual acuity was 6/15 (range 6/10 to 6/24) and at the final postoperative follow-up visit 6/9 (range 6/8.5 to 6/12). CONCLUSION: Zyoptix wavefront-guided LASEK for correction of residual myopia and astigmatism in keratoconus patients after INTACS insertion and stable refraction provided excellent visual outcome, with no loss of visual acuity and no complications.

Astigmatism↗

PubMed2006

[Lasik in myopic patients with congenital nystagmus].

PURPOSE: To present the results of IntraLASIK treatment in myopic patients with nystagmus. METHODS: Four patients, ranging in age from 25 to 49 years, with congenital nystagmus (8 eyes), underwent IntraLASIK surgery. Corneal flaps were made by Intralase femtosecond laser. In some patients, the eyes were fixated with forceps or a fixation ring during the laser ablation. In all patients, the effect of involuntary eye movements was neutralized by an active tracking system. RESULTS: The refractive errors were corrected in all cases. There was no decentration or loss of best corrected visual acuity by more than 1 line. In 3 of 8 eyes, the post-operative uncorrected visual acuity (UCVA) was equal or better than the best spectacles corrected visual acuity (BSCVA) preoperatively. Four of the 8 eyes retained or improved their BSCVA. CONCLUSIONS: Some patients with myopia and nystagmus may benefit from laser refractive surgery. By using the Intralase femtosecond laser and an active tracking system with or without mechanical fixation, laser refractive surgery may be safely and accurately performed in selected cases of nystagmus. Certain patients improve their BSCVA postoperatively.

Adult↗

PubMed2005

Keratoconus managed with intacs: one-year results.

OBJECTIVES: To describe the visual outcome of keratoconus managed with Intacs implantation (Addition Technology Inc, Fremont, Calif) and to define criteria that predict good outcome. METHODS: This retrospective, nonrandomized, comparative, consecutive case series studied 58 eyes of 43 patients with keratoconus managed by Intacs implantation. The outcome measures were analyzed pre-Intacs and 1 year post-Intacs. Preoperative parameters were correlated with outcome. MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), manifest refraction, videokeratography, and patient questionnaires. RESULTS: Intacs were implanted in all eyes with no intraoperative complications. Six eyes underwent additional Intacs surgery. Post-Intacs, the mean +/- SD UCVA improved from less than 20/200 +/- 0.1 line to 20/50(-3) +/- 3.1 lines, the mean +/- SD BSCVA was unchanged at 20/32 +/- 2.0 lines, the mean +/- SD spherical equivalent improved from -3.88 +/- 1.64 to -1.04 +/- 1.51 diopters (D), and the mean +/- SD astigmatism improved from 3.34 +/- 2.23 to 1.97 +/- 1.51 D. Twenty-five eyes had a good outcome (UCVA> or =20/40). Multiple regression selected BSCVA, astigmatism, and spherical myopia as the preoperative predictors of outcome. CONCLUSIONS: Intacs improve myopia and regular astigmatism in keratoconus. Milder keratoconus (BSCVA>20/32(-2) and astigmatism<3.50 D) and significant spherical myopia (>-1.75) predict better outcome.

Adult↗

PubMed2004

Single Intacs segment for post-laser in situ keratomileusis keratectasia.

PURPOSE: To describe the visual outcome of implantation of a single Intacs segment (Addition Technology Inc.) in eyes with keratectasia after myopic laser in situ keratomileusis (LASIK). SETTING: Private refractive surgery center, Jerusalem, Israel. METHODS: This retrospective, noncomparative, interventional, consecutive, small case series studied 5 eyes of 5 patients with post-LASIK keratectasia from 3 refractive laser centers treated by Intacs implantation. Before and 9 months after Intacs implantation, the uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), manifest refraction, keratometry, videokeratography, inferior-superior asymmetry, and patient questionnaires about visual function were assessed. RESULTS: Intacs implantation was performed 17 to 32 months post LASIK with no intraoperative complications and no loss of visual acuity. After implantation, the UCVA improved 8, 4, 3, 0.5, and 5 lines and the BSCVA, 2, 2.5, 1, 0.5, and 2 lines. The mean manifest refraction spherical equivalent improved from -1.60 diopters (D) +/- 1.67 (SD) to -0.80 +/- 1.05 D. The mean manifest astigmatic correction decreased from -3.9 +/- 2.96 to -2.46 +/- 2.77 D. Corneal topography showed improved inferior steepening and less irregular astigmatism. The mean inferior-superior asymmetry improved from 7.88 +/- 4.59 to 2.46 +/- 2.77 D. Self-reported visual symptoms improved significantly in Cases 1, 2, and 5 and slightly in Cases 3 and 4. CONCLUSIONS: Implantation of a single Intacs segment inferiorly appeared to improve progressive myopia and regular and irregular astigmatism in eyes with corneal ectasia after LASIK. With further study, this technique may prove to be an effective, relatively noninvasive approach.

Adult↗

PubMed2003

Wiping microkeratome blades with sterile 100% alcohol to prevent diffuse lamellar keratitis after laser in situ keratomileusis.

PURPOSE: To report our experience in preventing diffuse lamellar keratitis (DLK) after laser in situ keratomileusis (LASIK) by wiping the microkeratome blade with sterile 100% alcohol. SETTING: Enaim Refractive Surgery Center, Jerusalem, Israel. METHODS: Laser in situ keratomileusis was performed in 24 patients (48 eyes) on the same day by the same surgeon. The environment and instruments were identical in all cases. A new blade was used in both eyes of each patient. All blades were from the same batch and were randomly assigned to 2 groups. In the alcohol group, 12 blades were wiped with a Merocel surgical spear (Medtronic Solan) dipped in 100% alcohol and rinsed with balanced salt solution (BSS) before they were mounted in a Hansatome microkeratome (Bausch & Lomb Co.); in the control group, 12 blades were wiped with a Merocel surgical spear dipped in BSS and rinsed with BSS. All patients were examined on the first postoperative day. RESULTS: Grade I to II DLK was diagnosed in 7 eyes of 4 patients in the control group (29%). No DLK was diagnosed in the alcohol group. CONCLUSION: Wiping the microkeratome blade with 100% alcohol before mounting may remove a substance from the manufacturing or sterilization process that can cause DLK.

Anti-Infective Agents, Local↗

PubMedDate not supplied

Phototherapeutic keratectomy with mitomycin C for corneal haze following photorefractive keratectomy for myopia.

PURPOSE: To evaluate the safety and efficacy of phototherapeutic keratectomy (PTK) with single application of mitomycin C for patients with severe corneal haze following photorefractive keratectomy (PRK) for high myopia. METHODS: Eight eyes of seven patients were treated with PTK and intraoperative topical application of mitomycin C (0.02%) for severe corneal haze (grade 3) following PRK for myopia. RESULTS: All patients' visual performance improved significantly. Mean preoperative visual acuity (20/200 for both UCVA and BSCVA) improved significantly to 20/33 (0.6) and 20/30 (0.7) for UCVA and BSCVA, respectively. Six eyes (85.7%) had improved UCVA to 20/40 or better and gained five or more lines of UCVA. The corneal haze score decreased from grade 3 initially (for all eyes prior to PTK and mitomycin C) to a final mean haze score of 0.3 (range 0 to 0.5). Mean final spherical equivalent refraction achieved was -1.30 +/- 1.60 D (range -3.75 to +1.25 D). One eye gained only three lines of visual acuity due to regression and residual haze. No adverse effects related to the use of mitomycin C were recorded. CONCLUSION: PTK with a single intraoperative application of mitomycin C was safe and effective in reducing corneal haze and improving visual acuity in patients with severe corneal haze following PRK.

Adult↗

PubMedDate not supplied

Laser in situ keratomileusis for correction of myopia in eyes after retinal detachment surgery.

PURPOSE: To evaluate the safety and efficacy of laser in situ keratomileusis (LASIK) for correction of myopia in eyes with previous retinal detachment surgery. METHODS: A retrospective review was conducted of all consecutive eyes that underwent LASIK after retinal detachment surgery. Data was collected regarding previous ocular surgery and its time prior to LASIK, intra- and postoperative complications, and visual outcome measures pre- and postoperatively. RESULTS: Ten eyes with previous retinal detachment surgery were scheduled for LASIK. One eye was excluded from data analysis as LASIK was aborted due to inadequate microkeratome suction because of conjunctival scarring. Nine eyes underwent an uneventful LASIK procedure. On average, LASIK was performed 130+/-123 months following retinal detachment surgery. Postoperative LASIK follow-up was 14.8+/-12.5 months. No significant intraoperative, postoperative, or retinal complications were observed. The mean preoperative spherical equivalent refraction was -9.00+/-3.00 diopters (D), uncorrected visual acuity (UCVA) was 0.06+/-0.02, and best spectacle-corrected visual acuity (BSCVA) was 0.64+/-0.16. At the end of follow-up, the mean spherical equivalent refraction was 0.65+/-0.88 D, mean UCVA was 0.57+/-0.14, and mean BSCVA was 0.72+/-0.19. Differences between BSCVA before and after LASIK were statistically significant (P=.038). At final follow-up, the safety index was 1.22 and efficacy index was 1.01. CONCLUSIONS: Laser in situ keratomileusis was found to be a safe and efficient option for treating refractive errors in eyes with previous retinal detachment surgery.

Adult↗