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Biomedical subjects

Sande Bartels

Publications and source records attributed to Sande Bartels.

3 recordsLinked to original sources

Tracheal stenosis after percutaneous dilational tracheotomy.

OBJECTIVE: In many critical care units percutaneous dilational tracheotomy (PDT) has become an alternative to open tracheotomy. Although significant tracheal stenosis after PDT has been reported, the exact incidence is unknown. We report our findings on endoscopic laryngotracheoscopy for a group of patients who had undergone PDT more than 6 months before their examination. STUDY DESIGN AND SETTING: We did a retrospective review of 108 trauma patients who underwent PDT at least 6 months before enrollment in the study. Twenty-eight patients were either deceased or ineligible. Participation requests were mailed to the last recorded address of 80 patients. Thirty-four of those patients were contacted by phone, and 14 indicated their willingness to participate. Only 10 patients were able to make it to the clinic for examination. After transorally anesthetizing the hypopharynx and larynx with 4% lidocaine, each patient underwent flexible laryngotracheoscopy. Findings were categorized as normal or tracheal stenosis (<25%, 25% to 50%, or >50%). RESULTS: The tracheotomy site was virtually undetectable in 5 patients. In 4 patients, a scar was visible at the tracheotomy site, but there was no decrease in cross-sectional area. In 1 patient there was a 25% to 50% stenosis. All patients were completely asymptomatic with regard to airway and voice quality. CONCLUSION: One out of 10 patients in our series had a significant but asymptomatic stenosis after PDT. The risk of tracheal stenosis in PDT appears to be the same as that of open tracheotomy.

Adult↗

Evaluation of olfaction.

The sense of smell is often taken for granted until it is impaired or lost. Chemosensory disorders involving a decreased, absent, or distorted sense of smell can be devastating to those who suffer them and may have an impact on an individual's health, safety, and quality of life in a number of ways. It is necessary to approach the diagnosis of chemosensory disorders in a systematic manner that may reveal reversible pathology and to provide patients with counseling that can help them accommodate their disability.

Diagnosis, Differential↗

The impact of ethanol and tobacco smoke on intranasal epithelium in the rat.

BACKGROUND: Investigations have shown the influence of ethanol and tobacco smoke on olfaction, epithelial metaplasia, and cancer formation in the head and neck. Analysis of ethanol and tobacco smoke-induced histopathological mucosal changes in the upper respiratory tract may provide important insight into the pathophysiology of secondary olfactory dysfunction. METHODS: Three groups of laboratory rats were experimentally exposed to either ethanol, tobacco smoke, or both, with a control group having no such exposure. RESULTS: Compared with controls, histopathological analysis of nasal mucosa in exposed rats revealed a decrease in the length of olfactory epithelium, especially in the rats exposed to both ethanol and tobacco smoke. Structural changes included loss of cilia and metaplasia. CONCLUSION: The histological changes noted in rats after ethanol and tobacco smoke exposure, if relevant to human physiology, could explain the decreased olfactory ability seen in patients who use these products.

Analysis of Variance↗