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Biomedical subjects

Sanjay K Shetty

Publications and source records attributed to Sanjay K Shetty.

5 recordsLinked to original sources

Use of gadolinium chelate to confirm epidural needle placement in patients with an iodinated contrast reaction.

OBJECTIVE: When performing epidural steroid injections for the management of chronic back pain, imaging guidance and a limited epidurogram improve accuracy of needle placement and ensure appropriate delivery of the injectate into the epidural space. We describe our experience using a gadolinium chelate as an alternative contrast agent for limited epidurography in patients with a history of an iodinated contrast reaction. DESIGN: Thirty-eight of 2,067 (1.8%) epidural steroid injections performed in our department over a 25-month period (December 2003-January 2006) employed gadolinium. All injections were performed in the lumbar spine employing a paramedian interlaminar approach. Procedural notes and patient charts were reviewed to evaluate for immediate or delayed complications related to incorrect intrathecal or intravascular needle placement. A retrospective analysis of selected fluoroscopic spot images was performed to evaluate confidence of epidural needle placement; this analysis compared these spot images against those obtained from age- and gender-matched control patients in whom iodinated contrast was used to confirm needle placement. RESULTS: Real-time fluoroscopic guidance permitted confident visualization of an epidurogram at the time of procedure in all 38 cases as documented in the procedural report, and no procedure resulted in a complication due to incorrect needle placement. Retrospective review of fluoroscopic spot images revealed at least moderate confidence of epidural needle placement by both readers in 29/38 cases (76.3%). Fluoroscopic spot images obtained using gadolinium yielded significantly less confidence than images obtained in control patients whose procedures were performed using iodinated contrast (P < 0.01). However, operators were sufficiently confident in needle placement based on real-time fluoroscopic images (not available in our subsequent review) to inject anesthestic in all 38 cases, despite the immediate consequences that could result from intrathecal administration. During the same time period, there were 11/2,067 (0.5%) instances of intrathecal needle placement discovered during attempted epidurography despite the use of fluoroscopy for needle guidance and reliance on loss-of-resistance technique. CONCLUSION: Gadolinium chelate represents a safe and useful alternative contrast agent for confirmation of epidural needle placement in patients with an iodinated contrast allergy.

Adult↗

Fellowship directors' perceptions of the 2005 NRMP Radiology Fellowship Match.

RATIONALE AND OBJECTIVES: The aim of the study is to gauge radiology fellowship directors' experiences with the fellowship application process and perceptions of the National Resident Matching Program Radiology Fellowship Match, as well as compare these perceptions with those of senior residents. METHODS AND MATERIALS: An electronic survey was sent to 291 members of the Association of Program Directors in Radiology. Responses were compared directly with an earlier survey of senior residents who participated in the same cycle of the Fellowship Match. RESULTS: Sixty-seven respondents participated in the survey. Based on our estimates of the total number of US-based radiology subspecialty fellowship programs, this represents between 15.3% (67/438) and 24.2% (67/277) of all fellowship directors. Approximately three quarters (52/76 directors; 77.6%) participated in the Fellowship Match. Respondents believe that the match process makes the process fairer for all applicants (31/43 respondents; 70.5%) and primarily benefits residents (30/76 respondents; 60.0%), a significant difference compared with senior residents (P < .01). The majority of fellowship directors favor the current calendar and the ability to select internal candidates outside the Match. The majority of respondents believe that programs generally are not abiding by the rules of the Match (22/43 respondents; 51.2%), and at least 15 instances of rule violations were reported. A majority of fellowship directors favor continuing the Match in some form (26/42 respondents; 61.9%). CONCLUSION: Although there are significant differences in perception of the Match process between fellowship directors and senior residents, the majority of fellowship directors favor continuing the Match in some form. Several potential solutions, including explicit declaration of the number of available positions and strict enforcement of Match rules, may help improve the process in the future.

Chi-Square Distribution↗

Significance of incidental thyroid lesions detected on CT: correlation among CT, sonography, and pathology.

OBJECTIVE: The purpose of our study was to determine the prevalence of malignancy in incidental abnormalities of the thyroid gland detected on CT and to determine the relative accuracy of characterizing these abnormalities on CT as compared with sonography and pathology. MATERIALS AND METHODS: We searched our department's computerized clinical database for all thoracic and cervical CT scans in which a new abnormality was incidentally identified in the thyroid gland from 1998-2001. Two hundred thirty patients with abnormal findings in the gland on CT subsequently underwent thyroid sonography, and 118 of the 230 patients underwent a diagnostic biopsy or resection. CT and sonographic images were directly reviewed to identify imaging features of each thyroid abnormality, including the location, size, appearance, and presence or absence of calcifications. Associations were evaluated using Fisher's exact test of significance and the Student's t test. The overall rate of malignant and potentially malignant lesions among these incidental abnormalities of the thyroid gland was calculated. RESULTS: CT findings matched the sonographic characterization in 122 patients (53.0%), correctly identified the dominant nodule but missed multinodularity in 69 (30.0%) patients, and underestimated the number of nodules in 24 (10.4%) patients. CT overestimated the number of nodules in 5 (2.2%) patients and was false-positive for lesions in 10 patients (4.3%). Ninety-one patients with a single or dominant nodule on CT had pathologic correlation: 7 nodules were malignant, 17 showed malignant potential, and 67 were benign. Of 27 patients with multinodular or enlarged thyroid glands on CT and histopathologic correlation, 2 lesions were malignant and 25 benign. The presence of punctate calcifications on CT significantly correlated to the presence of microcalcifications on sonography (p < 0.02). Benign nodules were significantly smaller (mean, 2.16 +/- 1.01 cm; range, 0.6-4.5 cm) than malignant and potentially malignant nodules (mean, 2.79 +/- 0.99 cm; range, 0.7-4.6 cm) (p = 0.01). Patients 35 years or younger who had a thyroid lesion on CT were more likely to have malignancy (p < 0.01). Overall, among incidentally detected lesions of the thyroid gland, there was at least a 3.9% rate of malignancy (95% CI: 1.8-7.3%) and 7.4% rate of malignant potential (95% CI: 4.4-11.6%). CONCLUSION: There is at least an 11.3% prevalence of malignant or potentially malignant lesions among incidental thyroid abnormalities detected on CT. Patients 35 years or younger who have incidental abnormalities have a significantly greater rate of malignancy. No CT feature reliably distinguishes benign from malignant lesions in the thyroid gland. CT underestimates the number of nodules relative to sonography, which suggests that sonography is a useful adjunctive test after the incidental detection of a thyroid abnormality on CT.

Adult↗

CT perfusion in acute stroke.

As new treatments are developed for stroke, the potential clinical applications of CT perfusion (CTP) imaging in the diagnosis, triage, and therapeutic monitoring of these diseases are certain to increase. Technical advances in scanner hardware and software should no doubt continue to increase the speed, coverage, and resolution of CTP imaging. CTP offers the promise of efficient use of imaging resources and, potentially, of decreased morbidity. Most importantly, current CT technology already permits the incorporation of CTP as part of an all-in-one acute stroke examination to answer the four fundamental questions of stroke triage quickly and accurately, further increasing the contribution of imaging to the diagnosis and treatment of acute stroke.

Brain↗