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Biomedical subjects

Sarah Wessinger

Publications and source records attributed to Sarah Wessinger.

4 recordsLinked to original sources

Coping strategies and interpersonal support in patients with irritable bowel syndrome and inflammatory bowel disease.

BACKGROUND & AIMS: Coping strategies are used to manage conflict and illness and can have adaptive or maladaptive effects on health status. Perceived availability and quality of social support also influences health status. Coping strategies and social support have not been well studied in irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD). To understand their role better, coping strategies, social support, and psychiatric distress were assessed in patients with IBS and IBD and in controls. METHODS: Participants completed the Ways of Coping Questionnaire, the Interpersonal Support Evaluation, Symptom Checklist-90-revised, IBS-Quality of Life (QOL), and IBD-QOL. Participants also completed the Toronto Alexithymia Scale and Somatosensory Amplification Scale. RESULTS: The study population included 55 controls, 74 IBS patients, and 48 IBD patients. The IBS and IBD patients had higher scores on measures of psychiatric distress, alexithymia, and somatosensory amplification than controls, but did not differ from one another. QOL scores did not differ between patients with IBS and IBD. Patients with IBS and IBD reported significantly less interpersonal support than controls. Controls identified planful problem solving as the dominant coping strategy whereas patients with IBS and IBD relied significantly less on planful problem solving and positive reappraisal and more on escape-avoidance strategies. CONCLUSIONS: Compared with controls, IBS and IBD patients had increased levels of psychiatric distress, a poorer QOL, less interpersonal support, and greater reliance on passive coping strategies. These data suggest that psychosocial disturbances are common in IBD and IBS and suggest that the observed differences reflect illness behavior rather than a disorder-specific process.

Adaptation, Psychological↗

Small intestinal motility.

PURPOSE OF REVIEW: To review recently published studies presenting novel and relevant information on small intestinal motility in humans and animals. RECENT FINDINGS: Mechanisms of intestinal dysmotility in patients with pseudoobstruction and colonic inertia are becoming better clarified. The role of enteric flora in health and disease is an important and rapidly evolving area that will no doubt yield significant advances in the evaluation and treatment of many digestive disorders. The role of bacterial overgrowth in irritable bowel syndrome requires further study. The mechanisms underlying postoperative ileus are becoming both better understood and increasingly complex. Peripheral opioid antagonists may represent an important therapeutic advance in the treatment of ileus. Cannabinoids also appear to play a role in ileus and this echoes our rapidly evolving understanding of these compounds in the regulation of motility. SUMMARY: Small intestinal motility remains an understudied area. Recent publications have shed additional light on myogenic, neural, and hormonal control mechanisms.

Gastrointestinal Motility↗

Small intestinal motility.

PURPOSE OF REVIEW: To review recently published studies presenting novel and relevant information on small intestinal motility in humans and animals. RECENT FINDINGS: The reviewed studies covered a variety of topics with several themes emerging. The relation between bacterial overgrowth and altered intestinal motility gathers support in a variety of conditions including portal hypertension and senescence. The mechanisms of postoperative ileus are becoming better understood. Cannabinoids play an important role in ileus and this further highlights the importance of these compounds in intestinal motility. Luminal impedance appears to be an important tool for investigation of intestinal flow. SUMMARY: Small intestinal motility remains an understudied area. Recent publications have shed additional light on myogenic, neural, and hormonal control mechanisms. Novel investigative techniques will likely further improve our understanding.

Animals↗