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Biomedical subjects

Sarkis H Meterissian

Publications and source records attributed to Sarkis H Meterissian.

4 recordsLinked to original sources

A novel method of assessing clinical reasoning in surgical residents.

At present, surgical educators can readily assess knowledge with multiple-choice examinations, and inanimate models can be used to assess technical skills. Clinical judgment and reasoning are indispensable skills used by expert surgeons to solve ill-defined problems encountered in the emergency department, clinic, and operating room. The Script Concordance Test, a new tool of clinical reasoning assessment, can test the elaborated networks of knowledge that experienced surgeons develop over the years. It allows for multiple different approaches to the same problem and could be developed as both a formative and summative assessment tool in general surgery residency programs. This article explores the theoretical and practical aspects of the Script Concordance Test.

Clinical Competence↗

Successful use of letrozole in male breast cancer: a case report and review of hormonal therapy for male breast cancer.

Male breast cancer is an uncommon occurrence. Treatment of male breast cancer is typically extrapolated from data on the treatment of female breast cancer. Recently, aromatase inhibition has been proven as an effective therapy for female breast cancer, particularly in the setting of advanced cancers. The efficacy of aromatase inhibitors in males, however, has not been established. We report the successful treatment of a male with locally advanced breast cancer using the aromatase inhibitor letrozole.

Aged↗

A case of penile melanoma illustrating the low sensitivity of frozen sections in the assessment of sentinel lymph nodes.

A 75 year-old uncircumcised man presented with a 1.1mm thick malignant melanoma on the ventral aspect of the glans penis. He underwent isosulfan blue and technetium 99m guided sentinel lymph node (SLN) biopsy and distal penectomy with 2 cm margins. This is the third reported case of penile melanoma using both markers for SLN mapping. While frozen sections and H& E stains were negative, S-100 and HMB-45 immunohistochemistry revealed micrometastasis in one of the sentinel nodes. This case illustrates that any discussion with the patient about management and prognosis should await immunohistochemistry results.

Aged↗