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Satoshi Ishiko

Publications and source records attributed to Satoshi Ishiko.

4 recordsLinked to original sources

Association of preoperative photoreceptor displacement and improved central scotoma after idiopathic macular hole surgery.

OBJECTIVE: To investigate the relationship between preoperative photoreceptor displacement and postoperative scotoma after unilateral idiopathic macular hole surgery. DESIGN: Prospective nonrandomized comparative self-controlled trial. PARTICIPANTS: Twenty patients who underwent successful surgery for unilateral idiopathic macular hole participated in the study. METHODS: Kinetic perimetry using red and green filter glasses, black binocular fixation targets, and red and green selective monocular stimuli was performed preoperatively. Scanning laser ophthalmoscope (SLO) microperimetry was performed preoperatively and postoperatively. RESULTS: Sixteen patients had photoreceptor displacement preoperatively. In preoperative SLO microperimetry, all eyes with a macular hole had a scotoma; postoperatively, 12 of 16 had no scotoma. All four eyes with no preoperative photoreceptor displacement were noted to have a postoperative scotoma. The prevalence of postoperative scotoma in patients with preoperative photoreceptor displacement (4 of 16; 25%) was significantly lower than that in patients without preoperative photoreceptor displacement (4 of 4; 100%) (P = 0.03). CONCLUSIONS: The presence or absence of photoreceptor displacement preoperatively should affect postsurgical visual function. Photoreceptor damage may occur in eyes without photoreceptor displacement preoperatively, resulting in scotoma postoperatively.

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Detection of drusen in the fellow eye of Japanese patients with age-related macular degeneration using scanning laser ophthalmoscopy.

OBJECTIVE: To study the prevalence of drusen in the fellow eye of Japanese patients with age-related macular degeneration (AMD). DESIGN: Retrospective, cross-sectional study. PARTICIPANTS: Seventeen eyes of 17 Japanese patients with unilateral AMD. MAIN OUTCOME MEASURES: To compare the frequency of drusen based on photography and scanning laser ophthalmoscopy with confocal and ring apertures and a diode laser (780 nm). RESULTS: Using the scanning laser ophthalmoscope (SLO) with a ring aperture, drusen were detected clearly as in topographic imaging. In the fellow eyes of the study patients with AMD, photography showed drusen in 10 cases (58.8%); however, SLO imaging detected drusen in 15 cases (88.2%). The number of drusen detected using SLO imaging was significantly greater than when using photography (P < 0.05). CONCLUSIONS: Scanning laser ophthalmoscope imaging is superior to photography for detecting drusen in the fellow eyes of Japanese patients with unilateral AMD. The prevalence of drusen in the fellow eye of Japanese patients with AMD is much higher than previously speculated.

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Use of scanning laser ophthalmoscope microperimetry in clinically significant macular edema in type 2 diabetes mellitus.

PURPOSE: We used scanning laser ophthalmoscope (SLO) microperimetry to evaluate scotomas in patients with clinically significant diabetic macular edema (CSME) in type 2 diabetes mellitus. METHODS: We studied 19 patients (mean age = 63 years; range, 45-78 years) (19 eyes). SLO microperimetry was performed in all eyes. We divided patients into three groups as follows: dense scotoma, relative scotoma, and no scotoma. The following variables were documented: age; duration of diabetes, hemoglobin A(1c) levels; logarithm of the minimum angle of resolution (Log(MAR)) visual acuity; refractive power; a history of panretinal photocoagulation; presence or absence of proliferative diabetic retinopathy, vitreomacular separation, and cystoid changes; the type of macular edema; and stability of fixation. All variables were compared in the three groups. RESULTS: We identified 4 eyes (21.1%) with dense scotoma, 10 (52.6%) with relative scotoma, and 5 (26.3%) with no scotoma. There were significant differences in log(MAR) visual acuity among those with dense scotoma (1.4 +/- 0.5), relative scotoma (0.6 +/- 0.2), and no scotoma (0.2 +/- 0.3) (P <.05), and in the prevalence of cystoid changes, diffuse edema, and unstable fixation among those with dense scotoma (75%, 75%, and 100%, respectively), relative scotoma (20%, 30% and 50%, respectively) and no scotoma (0%, 0% and 0%, respectively) (P <.05). CONCLUSIONS: Macular scotoma was observed by SLO microperimetry in 74% of the patients in this study. A scotoma in CSME is related to the formation of cystoid changes and the type of macular edema. In eyes with CSME in type 2 diabetes mellitus, a scotoma in the macula causes visual acuity impairment and unstable fixation.

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