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Biomedical subjects

Scott D Weiner

Publications and source records attributed to Scott D Weiner.

9 recordsLinked to original sources

Bacterial Pyomyositis.

Bacterial pyomyositis has been defined as a subacute, deep bacterial infection of the soft tissues. The entity was originally described only in tropical climates, but it is increasing in incidence in temperate climates, such as in the United States. This is mainly attributed to the presence of immunocompromising states such as HIV/AIDS or liver disease. The etiology of pyomyositis remains a mystery, but its characteristics are well-described. If untreated, the disease process progresses through three distinct stages. The first stage is defined by vague complaints, muscle pain, and a low-grade fever. The second stage presents as worsening pain, swelling, fever, and actual abscess formation in the muscle. If the patient remains untreated, pyomyositis progresses to the third stage, which includes septicemia and possible septic shock. Large muscles around the pelvis are most commonly affected, and Staphylococcus aureus is the bacteria seen in most documented cases. To make a timely diagnosis and prevent serious sequelae, physical examination, laboratory results, imaging studies, and a high clinical suspicion must all be combined. Magnetic resonance imaging is the diagnostic study of choice, but it may be inconclusive early in the disease process. Definitive diagnosis must be made with aspiration or surgical drainage. Once diagnosed, treatment consists of appropriate intravenous antibiotics and possible surgical intervention. A full recovery is expected if appropriate treatment is initiated early in the process.

Journal Article↗

Enchondroma and chondrosarcoma of bone: clinical, radiologic, and histologic differentiation.

Intraosseous cartilage tumors are commonly encountered by orthopaedic surgeons during evaluation of a patient for undetermined pain; however, the possibility of missing a malignancy during examination is cause for concern. Surgery for enchondromas is not generally necessary but when clinical and radiographic features suggest a potential chondrosarcoma, prompt referral is necessary. Chondrosarcoma almost always occurs in adults. Patients usually present with pain and have characteristic findings on staging studies. Lucencies developing within the calcification, periosteal reactions, and a soft-tissue mass all are characteristic features of chondrosarcoma. Biopsies are not typically indicated because of the histologic similarity of benign and malignant cartilage lesions.

Biopsy↗

Osteochondritis dissecans involving the trochlea: report of two patients (three elbows) and review of the literature.

Osteochondritis dissecans (OCD) is an idiopathic lesion of subchondral bone resulting in separation of the articular cartilage and subchondral bone. Osteochondritis of the elbow primarily involves the capitellum. Only two cases involving the trochlea have been reported, one in the English literature and one in the German literature. Osteochondritis dissecans has been confused with other joint surface abnormalities, and therefore the orthopaedic literature must be read with scrutiny. Some of these other conditions include osteochondral fractures, osteonecrosis, accessory centers of ossification, and hereditary epiphyseal dysplasia. The authors describe two patients (one bilateral) with OCD involving the trochlea of the humerus. The first is a 12-year-old boy in whom an open biopsy was performed to rule out neoplastic lesions. The second is a 14-year-old boy with bilateral OCD that was recognized secondary to the similarity to the first patient. This patient was successfully treated conservatively. The first patient illustrates how recognition of OCD in the trochlea may prevent unnecessary biopsy. Osteochondritis dissecans should be part of the differential of lesions involving the trochlea.

Adolescent↗