Biomedical subjects

Sema Savci

Publications and source records attributed to Sema Savci.

7 recordsLinked to original sources

PubMed2006

Inspiratory muscle training in Morquio's syndrome: a case study.

We reported a case of MPS IV A presented with dyspnea on exertion and respiratory muscle weakness. The patient underwent inspiratory muscle training (IMT) using threshold loading for 18 weeks. After 6 weeks of initial IMT, aerobic exercise training consisting of walking was added to the treatment program. Inspiratory muscle strength increased 70%, and 6-minute walk test (6MWT) distance increased to 47 m. With the inclusion of aerobic exercise training, additional increases in inspiratory muscle strength (7%) and 6MWT distance (26.5 m) were obtained. Exertional dyspnea improved from severe to slight after 6 weeks of IMT, and to very slight after additional 12 weeks of combined aerobic training and IMT. Health-related quality of life improved especially in social function, emotional function, vitality, and physical role. In conclusion, inspiratory muscles can be trained with the improvement of muscle strength in a patient with Morquio's syndrome.

Adolescent↗

PubMed2006

Reduced pulmonary function in wind instrument players.

BACKGROUND: Wind instrument playing requires a strenuous respiratory activity. Previous studies investigating effect of wind instrument playing on pulmonary function are equivocal. METHODS: In the present study, 34 male, non-smoker wind players in a military band were compared with 44 healthy non-smoker males by pulmonary function testing. RESULTS: All spirometric values including forced expiratory volume in 1 sec (FEV1), forced vital capacity (FVC), FEV1/FVC, peak expiratory flow rate, forced expiratory flow in 25, 50, 75% of FVC, and during the middle half of the FVC were found significantly diminished in wind players. The class of wind instrument, brass or wood, showed no significant differences. FVC was significantly and negatively correlated with duration of practice. CONCLUSIONS: It was concluded that pulmonary function in wind players might be diminished probably due to development of asthma or constant barotrauma during their playing. This fact should be considered in clinical evaluation of wind instrument players.

Adult↗

PubMed2005

Six-minute walk distance as a measure of functional exercise capacity in multiple sclerosis.

PURPOSE: We hypothesised that six-minute walk (6MWT) distance of patients with ambulatory multiple sclerosis (MS)would differ from age-matched healthy control subjects. We also investigated the contribution of demographic, physical and physiological factors to impaired functional capacity in MS. METHOD: Thirty MS patients and 30 healthy subjects participated in this study. Respiratory muscle strength was measured. Pulmonary function test and 6MWT were performed. The Barthel Index (BI) was used to assess activities of daily living, and the Modified Ashworth Scale was used to determine spasticity. Symptomatic fatigue was measured using the Fatigue Severity Scale (FSS). RESULTS: Pulmonary function and respiratory muscle strength of ambulatory MS patients were significantly lower, and baseline heart rate and fatigue perception were significantly higher than were healthy controls (p < 0.05). MS patients reached a significantly higher exercise heart rate, and walked significantly shorter distance than did healthy subjects (p < 0.05). The BI score, baseline heart rate and FSS score together accounted for 81 percent variance in 6MWT distance of MS patients (p < 0.05). CONCLUSION: The shorter distance covered during a 6MWT is determined by the limitations in activities of daily living,resting heart rate and subjective symptomatic fatigue in ambulatory patients with MS. Respiratory muscle weakness, lung function and level of neurological impairment do not contribute to impaired functional exercise capacity in these patients.

Activities of Daily Living↗

PubMed2005

Functional capacity in severe chronic obstructive pulmonary disease.

OBJECTIVE: To investigate the functional capacity in patients with severe chronic obstructive pulmonary disease (COPD) and healthy subjects. METHODS: The present study was conducted in the School of Physical Therapy and Rehabilitation, Department of Chest Medicine, Medical School, Hacettepe University, Ankara, Turkey, from June 2002 to July 2003. Forty-five male patients with severe (23 moderately severe, 22 very severe) COPD and 45 healthy controls participated in the study. Pulmonary function tests and 6-minute walk test (6MWT) were performed. The Borg score and heart rate were measured before and after the test. External work of walking was calculated as the product of body weight and walked distance. Functional dyspnea was measured using the modified Medical Research Council (MRC) dyspnea scale. RESULTS: Both distance and external work of 6MWT were significantly lower in severe COPD patients than healthy subjects (p<0.05). No significant differences in distance, external work, and exertional dyspnea were found between moderately severe and very severe COPD patients (p>0.05). Patients with very severe impairment had a significantly lower percentage of predicted 6MWT distance (p<0.05). In these patients, 6MWT distance was correlated significantly with forced expiratory flow in one second (FEV1), MRC score, and Borg score whereas external work of walking correlated with age, FEV1, forced expiratory flow from 25-75%, MRC, and resting Borg score (p<0.05). CONCLUSION: Severe COPD patients had a significantly impaired functional capacity as compared to their healthy counterparts. Patients with FEV1 <35% have a lower percentage of functional capacity. Both distance and external work of 6MWT are influenced by large and small airway function, level of breathlessness reported during daily activity or scored during an exercise test in patients with FEV1 <35%.

Humans↗

PubMed2005

Factors determining self-efficacy in chronic obstructive pulmonary disease.

OBJECTIVE: We investigated the factors determining self-efficacy in patients with chronic obstructive pulmonary disease (COPD). METHODS: Thirty male patients with COPD and 30 healthy controls participated in the study. Pulmonary function tests, 6-minute walk test (6MWT), modified Borg scale, modified Medical Research Council (MRC) dyspnea scale, Hospital Anxiety and Depression Scale (HADS), Activities of Daily Living Questionnaire (ADL-Q), and COPD Self-Efficacy Scale (CSES) were used for the evaluation. The study was performed between September 2003 and May 2004 at the Department of Chest Medicine, School of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey. RESULTS: The COPD patients expressed higher depression and dyspnea level and impaired activities of daily living than healthy controls (p<0.05). Duration of disease and the ADL-Q score was significantly correlated with all subscales of CSES (p<0.05). Borg score and anxiety score were significantly related with negative affect, weather/environment, and behavioral risk factors subscales of CSES (p<0.05). Lung function was significantly related with physical exertion and behavioral risk factors, and 6MWT distance was significantly correlated with weather/environment and behavioral risk factors subscales (p<0.05). The MRC score was correlated with weather/environment score (p<0.05). The ADL-Q score and disease duration accounted for 76% of the variance in self-efficacy (p<0.05) CONCLUSION: Level of impaired activities of daily living due to respiratory limitation and the number of years since diagnosis are independent variables that predict self-efficacy, or level of confidence in engaging specific behaviors that lead to specific desired outcomes in COPD.

Activities of Daily Living↗

PubMed2005

[Poland syndrome (a case report)].

Poland syndrome is characterized with unilateral absence of pectoralis major muscle. Its incidence is one in 30000 live births. A 20 years old case with Poland syndrome is presented together with its clinical and laboratory features in this study. The case had anomaly of shortness of right hand fingers and syndactily between second and third fingers in addition to absence of right pectoralis muscle group. There was not another associated anomaly except aforementioned ones. Strength loss in abduction and adduction of right shoulder was detected with Cybex dynamometer. Furthermore decrease in predicted maximal inspiratory and expiratory pressures was detected.

Adult↗

PubMed2004

Active cycle of breathing techniques in non-invasive ventilation for acute hypercapnic respiratory failure.

We hypothesised that applying the active cycle of breathing techniques (ACBT) in patients with acute hypercapnic respiratory failure undergoing non-invasive ventilation would improve patient outcome. Thirty-four patients were randomised so that 17 patients with acute hypercapnic respiratory failure received the ACBT and non-invasive ventilation (ACBT group), and 17 patients received non-invasive ventilation alone (control group). The primary outcome measure was length of time requiring non-invasive ventilation, and secondary outcome measures were change in acute physiology score, change in arterial blood gas values, total duration of non-invasive ventilation, and length of stay in the intensive care unit. Although not significant, there was a greater decrease in arterial carbon dioxide pressure in the ACBT group compared to the control group (-21.41 mmHg vs -17.45 mmHg, p = 0.27). Total duration of ventilation tended to be shorter in the ACBT group than in the control group (64.9 hours vs 84.1 hours, p = 0.15). Length of time in need of non-invasive ventilation was significantly lower in the ACBT group than in the control group (5.0 days vs 6.7 days, p = 0.03). There was no significant difference in length of stay in the intensive care unit between the two groups (8.0 vs 9.4 days, p = 0.31). The use of ACBT may have positive effects in the treatment of patients with acute hypercapnic respiratory failure, resulting in a shorter length of time requiring non-invasive ventilation.

Acute Disease↗