Biomedical subjects

Semih Mumbuç

Publications and source records attributed to Semih Mumbuç.

9 recordsLinked to original sources

PubMed2005

Nasal angiomyolipoma.

Angiomyolipomas (AMLs) are hamartomatous lesions containing smooth muscle, vasculature and mature adipose tissue. AML occurs most frequently in the kidneys, with the liver being the second commonest site of involvement. Other localizations for AML are extremely rare and, to our knowledge, only six cases of AML of the nasal cavity have been reported to date. Our case involved a 52-year-old male who presented with a history of snoring and obstruction of the left nasal cavity. Physical examination revealed a 3-cm polypoid mass in the left nasal cavity, which was excised surgically. Histopathologic examination revealed that the lesion was composed of smooth muscle bundles, mature adipose tissue and blood vessels of different sizes. No epitheloid smooth muscle cells were observed and HMB-45 staining was negative. In conclusion, although nasal AML is a rare lesion, it should be considered in the differential diagnosis of polypoid nasal masses, especially when the mass occurs unilaterally.

Actins↗

PubMed2005

Tuberculous deep neck infection in a soldier, preceding miliary tuberculosis: a diagnostic dilemma.

Tuberculosis can affect every organ, most importantly the lungs, and worldwide it is the leading cause of death attributable to a single infectious agent. Tuberculous involvement of the neck is also possible. Patients mostly present with masses or draining fistulas in the neck, which are mostly located in the posterior cervical, submandibular, and supraclavicular regions. We report on a soldier who presented with a tuberculous deep neck infection, followed by miliary tuberculosis. The clinical presentation and diagnostic dilemmas are discussed.

Adult↗

PubMed2004

An analysis of the single-stage tympanoplasty with over-underlay grafting in tympanosclerosis.

OBJECTIVES: Our objective was to analyze the results of tympanosclerosis surgery using over-underlay tympanoplasty and to find out the effect of single-stage surgery on hearing results. MATERIALS AND METHODS: Forty-two patients who were operated on for tympanosclerosis between July 1998 and February 2002 were included in the study. These were one-stage tympanoplasties, because second-stage operations and revisions were not included. Operative records and audiograms of the patients were obtained. Of the patients, 48% had bilateral tympanosclerosis. In three (7.1%) of the patients, tympanosclerosis and cholesteatoma occurred concomitantly. The cog was present in eight (20%) of 40 mastoidectomies. Körner's septum was present in nine (22.5%) patients. The graft take rate was 95.2%. RESULTS: The pre- and postoperative air-bone gap values of the patients were not significantly different (p > 0.05). Thirty-three percent of the patients met the successful hearing criteria (air-bone gap <20 dB). However, 47% had an air-bone gap closure between 20 dB and 30 dB, whereas 20% had a gap of more than 30 dB. CONCLUSION: Single-stage surgery does not result in a satisfactory hearing improvement in most of the patients with tympanosclerosis. Only one third of the patients, most of whom had a mobile stapes, had satisfactory hearing results. Mobilization of a fixed stapes is not an effective option for hearing restoration in tympanosclerosis. Second-stage surgery for stapedectomy and placement of a prosthesis-like piston or total ossicular replacement prosthesis should be considered to obtain better hearing results in tympanosclerosis.

Audiometry, Pure-Tone↗

PubMed2004

[Management of paediatric neck masses].

OBJECTIVES: The present study was designed to demonstrate the regional distribution prevalence and management differences of certain pediatric neck masses in this region of the country. PATIENTS AND METHODS: Fifty-five patients with pediatric neck masses, who were diagnosed and treated surgically were retrospectively analyzed. RESULTS: Analysis of 55 patients showed that congenital neck masses were the most common pathology in pediatric neck masses (47%), followed by infectious and tuberculous lymphadenopathies (24%). CONCLUSION: It can be concluded from the study that besides the age group and the characteristics of the neck mass, life standards of the region is also an important factor to be considered.

Adolescent↗

PubMed2004

A giant granular cell tumor of the tongue in a pediatric case.

Granular cell tumor (GCT) is an infrequent and usually benign neoplasm which is found predominantly in the head and neck region. More than half of the head and neck GCTs originate from the tongue. It is most frequently seen in the fourth to sixth decades of life. We presented an interesting case of a giant GCT in a 2.5-year-old patient. It was located under the anterior tongue, filled the floor of the mouth and was resected by the transoral route.

Child, Preschool↗

PubMed2003

A unique case of an epidermoid cyst of the pterygopalatine fossa and its management.

Epidermoid cysts are rare benign tumors that are derived from the development of abnormally situated ectodermal tissue. Although they may originate from any part of the body head and neck region is occasionally affected. Epidermoid cyst originating from pterygopalatine fossa has not been reported previously in the literature. We report the first case of epidermoid cyst of pterygomaxillary fossa in this study.

Child, Preschool↗

PubMed2003

Otogenic cerebral venous infarction: a rare complication of acute otitis media.

A case of cerebral venous infarction (CVI) as a complication of acute otitis media (AOM) was presented in a 16-month-old male patient. The patient admitted with AOM in the right ear, ipsilateral facial paralysis and contralateral hemiplegia. Computerized tomography of the brain showed low density areas involving both the cortex and subcortical white matter in the right frontoparietal region, and there were patchy and multifocal enhancing areas with intravenous contrast enhancement. These findings disclosed the diagnosis of venous infarctions involving the superficial cortical veins on the right side. Complete recovery was achieved with 2 weeks of sulbactam-ampicilline, amikacin and prednisolone treatment. Although it is rather rare, CVI should also be remembered among the otogenic intracranial complications.

Acute Disease↗

PubMed2002

Inflammatory myofibroblastic tumor (inflammatory pseudotumor) of the maxillary sinus mimicking malignancy: a case report of an unusual location (is that a true neoplasm?).

The inflammatory myofibroblastic tumor (IMT) is a space-occupying lesion of unknown etiology and a distinctive but controversial lesion. This type of tumor is recently considered neoplastic rather than inflammatory. It is usually occurring during childhood, composed of fascicles of bland myofibroblastic cells admixed with a prominent inflammatory infiltrate consisting of lymphocytes, plasma cells, and eosinophils. IMT of the maxilla is very rare. The diagnosis of IMT can be made on the basis of histopathology and immunohistochemistry. Herein, we presented a patient who had IMT of the maxillary sinus that was initially misinterpreted as a malignant neoplasm upon clinical and radiographic examinations. We discussed the diagnostic and therapeutic procedures and may consider it a true neoplasm.

Combined Modality Therapy↗

PubMed2002

Malignant triton tumor of the supraclavicular region arising after radiotherapy.

Malignant triton tumor (MTT) is a relatively rare, aggressive tumor comprised of both malignant schwannoma cells and malignant rhabdomyoblasts. Only three cases of MTT which arose after radiation therapy were reported in the literature. We presented an additional case of MTT arising after radiotherapy and discussed its clinical and pathological characteristics.

Adult↗