Biomedical subjects

Senad Mehmedbasić

Publications and source records attributed to Senad Mehmedbasić.

5 recordsLinked to original sources

PubMed2005

[The frequency of female genital cancer at Gynecological Department in Cantonal Hospital Zenica--before, during and postwar time in Bosnia-Herzegovina].

This targeted, retrospective, descriptive, controlled and open study comprises the last decade of the 20th Century and all histologically verified malign tumours at the Cantonal Hospital Zenica. By analysing pathohistological findings, 865 malign genital tumours were found; where the most numerous were cervical maligns (70.06%), then corporal (17.34%), ovarian (10.40%), vulvae 1.16%, vaginal 0.69% and tubal 0.35%. Malign frequency curve shows continual decrease till the war year 1993 and continual increase from that period till 2000. The most frequent type of malign tumour is carcinoma with the frequency of over 98% (70.06% carcinoma planocellulare, 27.86 adenocarcinoma), while recently literature shows a bit over 90% of frequency. More than 3/4 of all malign genital tumours were discovered in nullity and first clinical stages. Results show that approximately 9/10 of all malign processes in female genital tract occurred at uterus. The most frequent are malign tumours that are histologically best differentiated, while the least frequent are those that are insufficiently differentiated. Malign diseases, due to cervical cancer, which encumbers more than half of the cases, mostly afflict age group of 35-49, while the age group 50-64 is mostly afflicted by corporal and ovarian malign tumours. Comparing the year 1991 with 1993, 1995, 1997 and 1999, no statistically significant difference was found occurrence of menarha at women who have cervical, corporal and ovarian malign tumours (p>0.05).

Adult↗

PubMed2005

[Perinatological aspects of mutual relationships between asthma and pregnancy].

We have researched influence of asthma on pregnancy, fetus and delivery. We have verified asthmatic pregnant women on the basis of the relevant medical documentation (N=42). Control group is made of healthy pregnant women selected under the FIGO criteria (K=100). We followed up influence of asthma on pregnancy by evaluation of 6 variables which are determinants of pregnancy quality (spontanious abortion, missed abortion, hyperemesis gravidarum, EPH gestoses, prematurity and over-carried pregnancy. Authors didn't find any statistical significance in influence of asthma on pregnancy quality although the level of pathological situations in all researched variables was about 25% higher than in control group. In over-carried pregnancy variable statistically significant low level of cases was found in researched group. Influence of asthma on fetus was monitored with the methods of clinical measurements of fetuses biophysical profile, cardiotocographic index and amnioscopy. Significantly higher participation of pathological situations was found in all three monitored variables within researched group of pregnancies (p<0.01). We have monitored influence of asthma on delivery with the methods of clinical measurement ABS pregnant-asthmatic woman, ABS of the new-born baby, body mass of new-born baby and the kind of delivery. A statistically significant fall of pp O2 (p<0.01) was found as well as declination of actual pH of pregnant-asthmatic woman toward acidosis (p<0.01) during the second delivery stage. Kind of delivery is showing statistically high level of participation of surgical termination of delivery in researched group (SC and vacuum extraction)--(p<0.001).

Adult↗

PubMed2004

[Erectile dysfunction--incidence, causes and risk factors].

The inability of a male to attain and maintain an erection sufficient to allow vaginal penetration is called erectile dysfunction. It is a part of general male sexual dysfunction called impotence, which also includes libidinal, orgasmic and ejaculatory dysfunction. Erectile dysfunction affects millions of men and although it may not mean a total loss of sexual satisfaction, it often creates a mental stress that affects the man's quality of life. Knowledge of erectile dysfunction has increased remarkably over the past decade. Nowadays, about 50-85% of erectile dysfunction patients can be shown to have a somatic cause by modern methods of examination. Erectile dysfunction may also occur as a result of specific illness or medical treatment, and it is often multifactorial in etiology. Erectile dysfunction increases with age.

Erectile Dysfunction↗

PubMed2004

[Therapy of erectile dysfunction--public health aspects].

Erectile dysfunction (ED)--the consistent or recurrent inability of a man to attain and/or maintain, a penile erection sufficient for sexual performance--is a common health condition among men that is largely untreated. It is estimated that some degree of ED affects more than one half of all men over the age of 40--152 million men worldwide. That is a big problem, that needs appropriate treatment. After diagnostic evaluation of the patient, doctor decides what is the best treatment option for the patient, following his health condition. Choice of treatment options: physio-sexual therapy, oral drug therapy, topical drug therapy, transurethral drug therapy, intracavernosal therapy, hormonal treatment, vacuum devices and surgery. Nowadays the most important contemporary treatments of ED are peroral sildenafil and intracavernosal pharmacotherapy using vasoactive medicines. However, these drugs are not suitable to every patient. More noninvasive methods to treat ED, such as oral medication or locally applicable preparations are needed.

Adult↗

PubMed2003

[Color-Doppler ultrasonography in the diagnostic evaluation of erectile dysfunction].

UNLABELLED: Color-Doppler sonography (CDS) of the cavernosal arteries has received considerable attention since its description in 1985 by Lue et al. Color and Spectral Doppler analysis, provides a useful noninvasive means of evaluating both morphologic and hemodynamic penile abnormalities. CDS is the best method in diagnostic evaluation of patients with erectile dysfunction. It assesses the integrity of the arterial supply to the penis and provides some useful information on the veno-occlusive mechanism. Because the arterial diameter and flow rate change during the different phases of erection CDS is performed after pharmacostimulation with vasoactive agents. Purpose of this study is diagnostic evaluation patients with erectile dysfunction. PATIENTS AND METHOD: We studied 60 patients suspected for vasculogenic ED, and 30 patients suspected for psyhogenic ED, assessing the morphodynamic features of cavernosal arteries by Color-Doppler sonography and their response to contravaernosal injection of prostaglandin E1 (PgE1) and oral dose of Sildenafil citrate. Morphodynamic parameters evaluated by color Doppler sonography included: peak systolic velocity, endodiastolic velocity, inner arterial diameter, index and acceleration of penile blood flow. Patients were divided in the groups: A group (A1--10 patients < 35 years of age, A2--20 patients > 35 years of age) underwent pharmacotest with ICI PgE1; B group (B1--8 patients < 35 years of age, B2--22 patients 35 years age) were tested with oral dose of Sildenafil citrate and C group--30 patients who were also tested with the same drug. CONCLUSION: The CDS may be used to evaluate the hemodynamic parameters of the erectile dysfunction. Arterial insufficiency is suspected with poor blood flow, while veno-occlusive dysfunction is inferred in the face of adequate blood flow and poor erectile response.

Adult↗