Biomedical subjects

Serge Mensah

Publications and source records attributed to Serge Mensah.

4 recordsLinked to original sources

PubMed2006

A 2-D anatomic breast ductal computer phantom for ultrasonic imaging.

Most breast cancers (85%) originate from the epithelium and develop first in the ductolobular structures. In screening procedures, the mammary epithelium should therefore be investigated first by the performing of an anatomically guided examination. For this purpose (mass screening, surgical guidance), we developed a two-dimensional anatomic phantom corresponding to an axial cross section of the ductolobular structures, which makes it possible to better understand the interactions between the breast composition and ultrasound. The various constitutive tissues were modeled as a random inhomogeneous continuum with density and sound speed fluctuations. Ultrasonic pulse propagation through the breast computer phantom was simulated using a finite element time domain method (the phantom can be used with other propagation codes). The simulated ductal echographic image is compared with the ductal tomographic (DT) reconstruction. The preliminary results obtained show that the DT method is more satisfactory in terms of both the contrast and the resolution.

Algorithms↗

PubMed2005

Soft tissue absorption tomography with correction for scattering aberrations.

Among the many factors involved in ultrasound attenuation phenomena, scattering effects play a major role, even in the unexpected case of soft tissues. It is proposed in this study to quantitatively evaluate the scattering affecting the measurements before reconstructing the absorption parameter alone. The reconstruction procedure involves three steps: (1) Estimating the sound speed map using a transmission tomography algorithm. This estimation procedure provides a numerical phantom of the organ probed, cleared of all dissipative components. This absorption free phantom mimics the (viscoacoustic) tissues imaged except for the density and absorption characteristics: the density a priori equals 1000 kg/m3 and the absorption is not taken into account. The impedance fluctuations in the object are therefore approximated on the basis of the sound speed contrast. (2) Synthesing the field scattered by the absorption free phantom; the attenuation observed here results solely from the scattering phenomenon. The synthesis is carried out using a finite-element time domain code simulating the ultrasonic propagation through the phantom. It provides the scattering distortion reference introduced into the log spectral absorption estimator. (3) Reducing the scattering distortions affecting the integrated absorption measured along the ray paths using a log spectral procedure. The corrected integrated absorption is then processed using a tomographic reconstruction procedure that provides an estimate of the absorption distribution. Simple numerical simulations show the improvement obtained in the absorption estimates with this approach.

Absorption↗

PubMed2003

Weakly inhomogeneous media tomography.

Our objective is to develop an ultrasonic scanner for breast imaging. High resolution is obtained by using wide-band spherical waves transmitted and measured in the near field zone (i.e., close to the skin) all around the organ. The tomographic approach that we adopt allows us to use low central frequency waves (3-7 MHz) that are suitable for good penetration while maintaining high resolution and contrast. The procedure is thus suitable for early detection of tumors and increases the chances of total recovery. The novelty of the present reconstruction procedure is that it associates the signals acquired in transmission to the data measured in reflection over a large aperture. This enables us to correct the phase aberration induced by weak inhomogeneities whose sizes might be several wavelengths. Numerical tests based on Finite Difference Time Domain (FDTD) simulations demonstrate the greater fidelity of the reconstruction.

Algorithms↗

PubMed2002

Near-field diffraction tomography.

We propose an algorithm that deals with broadband ultrasonic signals acquired in the near-field domain using probes close to the skin. This technique is designed for diffraction tomography of compact support objects interrogated by spherical waves (small transducers). It is an approximate inversion procedure in the Born approximation based on elliptical backprojection. Near-field imaging is enhanced by reducing the geometrical distortion observed on standard tomography. Numerical tests based on finite difference time domain (FDTD) simulations of data scattered by a tissue-like phantom are given.

Algorithms↗