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Biomedical subjects

Sergio Santamaria

Publications and source records attributed to Sergio Santamaria.

3 recordsLinked to original sources

The use of the neuronavigator in the orbital surgery of a rare case of Rosai-Dorfman disease.

Neuronavigators are robotic devices that can help to bridge the gap between the data of three-dimensional images and the object by means of interactive computerized programs. A rare case of Rosai-Dorfman disease with prevalent bilateral endo-orbital interest is reported, in which an assisting neuronavigation system was used. The navigation system used is a stereotaxic system without the use of supporting mechanical arms, permitting bi-dimensional and tridimensional reconstruction through the data that are obtained from diagnostic equipment such as computed tomography, magnetic resonance imaging, single photon emission computed tomography, and positron emission tomography. This system has given an accurate localization of the pathological findings and has permitted a precise evaluation of the relation between the lesion and intraconical structures, which are fundamental requisites to optimize the treatment and reduce the postsurgical complications. The exciting results achieved in cerebral parenchyma surgery motivate extension of the use of neuronavigator systems to the splanchnocranial complex.

Adolescent↗

Endo-orbital osteoma: two case reports.

Osteoma is a benign, slow-growing tumor, which mainly occurs in the bones and cavities of the middle third of the face, representing the most frequent benign tumor of the paranasal sinuses. Osteoma of the paranasal sinuses is generally asymptomatic and it is discovered only as a coincidental radiological finding; when it becomes symptomatic, the most common presenting symptoms are headaches and facial pain. Rarely the sinusal osteoma may entail secondary orbital extension, with ocular signs and symptoms. Primary intraorbital involvement is extremely rare. The authors present a review of the literature and report two cases of primary orbital osteoma. In both cases surgical treatment led to the complete remission of symptoms. Diagnosis and surgical therapy are discussed.

Adult↗

Prophylactic thyroidectomy in MEN 2A syndrome.

Genetic testing is the appropriate procedure in MEN 2A syndrome for the early diagnosis of medullary carcinoma even at a preclinical stage. Prophylactic total thyroidectomy represents the standard preventive and therapeutic surgical approach in the treatment of medullary thyroid carcinoma in MEN 2A syndrome. Our experience has confirmed the presence of CCH and medullary thyroid carcinoma even in clinically negative patients, in agreement with reports in the literature.

Adult↗