Native valve endocarditis with persistent embolization due to Neisseria mucosa.
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Journal Article↗
Biomedical subjects
Serhat Unal
Publications and source records attributed to Serhat Unal.
Political issues in internal medicine in Europe.
What will be the future of Internal Medicine in Europe? Because of rapidly growing concerns regarding the position of Internal Medicine in many European countries, the European Federation of Internal Medicine has established a working group to analyze the situation. Being well aware of the variation of working practices in the different countries, the members of the group used an "all-European" approach to answer the following questions: Are there problems for Internal Medicine, what problems and why? Why do the health care systems of the European countries need Internal Medicine? Why do the patients need Internal Medicine? What needs to be done? Internal Medicine is the modern, clinical and scientific medical discipline taking care of adult patients with one or more complex, acute or chronic illnesses. Internal Medicine is the cornerstone of integrated health care delivery service that is needed today. Decision-makers in politics and hospitals, insurers, journalists and the general public need a better understanding of what Internal Medicine can offer to the health care system and to the individual patient.
Europe↗
[Screening for Neisseria gonorrhoeae and Chlamydia trachomatis in human immunodeficiency virus positive men without urethritis symptoms].
Some of the sexually transmitted diseases' agents other than human immunodeficiency virus (HIV) take an active part in transmission of HIV infection. The objective of the study was to determine the prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae in 18 HIV positive men without urethritis symptoms and in 70 HIV negative men with urethritis symptoms as control group. The urine samples were screened for C. trachomatis and N. gonorrhoeae using polymerase chain reaction (PCR). The prevalence of N. gonorrhoeae in HIV positive men without urethritis symptoms was significantly higher than that in HIV negative men with urethritis symptoms (p<0.05). HIV positive individuals should be considered as a high-risk group in respect to the other sexually transmitted diseases, thus necessitating screening for N. gonorrhoeae in order to break the infectious chain in these patients.
Adult↗
[Antimicrobial resistance of Neisseria gonorrhoeae strains isolated from sex workers in Ankara].
The prevalence of gonococcal infections among sexually transmitted infections is decreasing particularly in developed countries, but the increase in antimicrobial resistance of Neisseria gonorrhoeae is an emerging issue. There is lack of data about the epidemiology and the resistance pattern of the pathogen in our country. Gonococcal infections are recently included among the reportable diseases in Turkey. The specific laboratory tests are difficult, expensive and seldomly used for diagnosis in our country. The infection is usuallly treated empirically. In this study, 30 N. gonorrhoeae strains isolated from clinical samples (endocervical, rectal and urethral swabs) obtained from registered/unregistered sex workers admitted to Ankara Municipiality Hospital of Dermatology and Venereal Diseases were tested for beta-lactamase production and the susceptibility to various antimicrobials. The susceptibility testing was performed by agar dilution method, and the results were evaluated according to Clinical and Laboratory Standards Institute (CLSI) recommendations. Of the isolates, 70% was found resistant to penicilin and beta-lactamase production was observed in 48% of them. The susceptibility rates of the isolates to ceftriaxone, cefixime, ciprofloxacin, and tetracycline were found as 100%, 100%, 97%, and 40%, respectively.
Anti-Infective Agents↗
[The colorful clinical spectrum of cerebral toxoplasmosis in five HIV positive cases: what comes out of Pandora's box?].
In patients with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS), the most common cause of focal intracranial lesion is Toxoplasma gondii infection. T. gondii encephalitis is an easily and effectively treatable disease, with promising outcomes. T. gondii has the potential to form a focal infection niche anywhere in the central nervous system, thus allowing for a colorful clinical picture. In this report, we attempted to present five HIV/AIDS cases with central nervous system toxoplasmosis demonstrating five different neurological presentations. The ages, gender and clinical findings of the patients who were admitted to our Infectious Diseases Clinics were as follows; 35 years old male patient with delirium, 49 years old male patient with focal dystony, 32 years old female patient with facial paralysis and monoparalysis, 53 years old male patient with Wernicke syndrome, 32 years old male patient with epilepsy. Cerebral toxoplasmosis were diagnosed by clinical findings and imaging techniques. The patients were treated with trimetoprim-sulfametoxazol (TMP-SMZ) and haloperidol, only TMP-SMZ, clindamycin and daraprim, TMP-SMZ and levotiracetam, TMP-SMZ and phenytoin, respectively, with recovery in neurological and radiological symptoms. In conclusion, until proven otherwise, HIV/AIDS patients presenting with focal neurological complaints should be accepted as having central nervous system toxoplasmosis.
Acquired Immunodeficiency Syndrome↗