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Biomedical subjects

Sevtap Günbay

Publications and source records attributed to Sevtap Günbay.

2 recordsLinked to original sources

Quantitative morphometric evaluation of critical size experimental bone defects by microcomputed tomography.

Our aim was to show that microcomputed tomography is a useful tool for acquiring high-resolution three-dimensional tomographic images to assess bone healing, the interface with materials, and the biocompatibility of bone substitutes. Acquired images can be used for non-invasive quantitative morphometric analysis of regenerating bone, leaving the option for conventional histology to be an adjunct used at defined intervals. The temporal characterisation of the mineralisation of bone potentially has a critical role in the understanding of the dynamics of mineralisation of healing bone. This has applications both for degradable and bioactive materials and for pharmaceutical products that act on bone. Formal validation of this promising new technique will be a critical part of continuing studies.

Animals↗

Atypical presentations of pediatric actinomycosis: report of a case.

It is well recognized that cervicofacial actinomycosis is rare in children, especially at maxilla. Actinomycosis involving the maxilla usually is seen as a localized intraoral infection in contrast to classical cervicofacial actinomycosis. In this article, we describe an 8-year-old patient who had actinomycosis involving the bone at the left maxillary lateral incisor region. The diagnosis was based on histologic report because of location and development of the lesion with unusual history. The treatment of choice was removal of the soft and hard tissues with concomitant prolonged penicillin administration. In cases of persistent oral infection the diagnosis of actinomycosis should be actively attempted through microbiologic and histologic examination.

Actinomycosis, Cervicofacial↗