Biomedical subjects

Seyda Ugurlu

Publications and source records attributed to Seyda Ugurlu.

3 recordsLinked to original sources

PubMed2005

Coccidioidomycosis of the eyelid.

A 77-year-old woman presented with an ulcerated nodule on her right lower eyelid that was unresponsive to broad-spectrum antibiotics or incision and drainage. Coccidioidomycosis was suspected because of previous serologic testing and concurrent indurated cutaneous nodules. Although skin biopsies were not diagnostic, cultures from the eyelid were positive for Coccidioides immitis. The patient was initially treated with oral fluconazole, with resolution of the eyelid and skin lesions. She ultimately completed a 6-month course of oral azole therapy, and at 18-month follow-up she was symptom free. Few cases of granulomatous coccidioidomycosis of the eyelids have been reported. The clinical features of this infection are not specific, and the diagnosis is often difficult. Presentation can mimic bacterial infection or malignant neoplasm, leading to delayed or inappropriate treatment. We describe an unusual ulcerative lesion of the eyelid that led to a diagnosis of disseminated coccidioidomycosis.

Aged↗

PubMed2004

Evolution of an orbital apex tumor over a decade.

We report the evolution of an orbital apex tumor that underwent spontaneous regression, followed several years later by rapid growth and loss of vision. A turkey farmer had a right apical lesion, initially thought to be an optic nerve meningioma. The mass spontaneously regressed over 2 years, with marked improvement of vision. Eight years later, the patient presented with loss of light perception and severe proptosis of the right eye from a massive orbital tumor that extended in the cavernous sinus. An eyelid-sparing orbital exenteration was performed. The pathologic diagnosis was diffuse large cell lymphoma. This case demonstrates that non-Hodgkin lymphoma of the orbital apex may resolve spontaneously or it may enlarge rapidly, degenerating into more aggressive forms.

Aged↗

PubMedDate not supplied

Strabismus in Down syndrome.

PURPOSE: To determine the distribution of refractive errors and clinical characteristics of strabismus in patients with Down syndrome. PATIENTS AND METHODS: Patients with Down syndrome attending the Izmir Association for Supporting Patients With Down Syndrome in Izmir, Turkey, were screened for strabismus and refractive errors. All patients underwent a complete eye examination including cycloplegic refraction and dilated fundus examination. Ocular alignment was evaluated using the cover test and either the Krimsky or the Hirschberg corneal reflex test depending on the cooperation of the patient. Strabismic and nonstrabismic patients were compared for refractive errors, anisometropia, and amblyopia. RESULTS: Fifty-seven patients with an average (+/- standard deviation) age of 9.30 years (+/- 6.14 years; range, 1 to 31 years) were screened. Twenty-five (44%) were female and 32 (56%) were male. Eleven patients (19%) had strabismus. Ten (18%) had esotropia and 1 (2%) had exotropia. Infantile esotropia was observed in 3 patients who had no significant refractive errors. Seven patients had acquired esotropia; they had clinically significant refractive errors and anisometropia. A higher frequency of hypermetropia was noted in patients with strabismus (P < .05). CONCLUSIONS: Esotropia and hypermetropia are common in patients with Down syndrome. Early diagnosis and treatment of strabismus and associated ocular conditions such as refractive errors and amblyopia may improve the quality of life for these patients.

Adolescent↗