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Biomedical subjects

Shai Luria

Publications and source records attributed to Shai Luria.

5 recordsLinked to original sources

Evaluation of CO2 accumulation in respiratory protective devices.

A simple mathematical model was developed to grade the results of the fraction of inspiratory CO2 levels in respiratory protective devices (RPDs). Using this model, the level of FiCO2 of two chemical warfare RPDs was monitored during the examination of 54 young male volunteers at rest and exercise. No set of results distributed in a normal Gaussian mode; therefore, parametric statistics could not be used to analyze the group's results. Yet the model allowed simple and insightful evaluation of the results, stressing differences between the similar RPDs. We suggest continued use of the analysis model as a tool for quantitative evaluation of results and further understanding of the respiratory patterns of RPDs.

Adult↗

[Using thalidomide against pathological neovascularization].

Thalidomide was first used during the 50's-60's, especially for morning sickness in pregnant women. It was found to be a powerful teratogen only years later and was banned from use. At the same time it was found to have anti-inflammatory and anti-angiogenic properties and was approved as treatment for leprosy. As such, thalidomide might be used against pathological neovascularization, as seen in mustard gas exposure. From past experience we know that the eyes are the most vulnerable organ to mustard gas exposure. In some of the casualties there is a late sequella including pathological corneal neovascularization. So far there is no specific effective treatment against this neovascularization. The purpose of this review is to examine current research about the potential use of thalidomide as an anti-angiogenic agent, including potential role in treating mustard gas eye injury.

Angiogenesis Inhibitors↗

[Medical aspects of the lacrimator CS].

Since the 1960's, CS has become the main riot control agent in use by police and army forces throughout the world. The first post-exposure symptom is a burning sensation in the eyes, nose and throat. At a later stage, lacrimation, rhinorrhea, conjunctivitis, sore throat and salivation appear. These symptoms are followed by chest pain and dry cough, and if the substance is swallowed, it may cause nausea and vomiting. This article reviews the physical properties of CS, the main dispersing techniques, the clinical signs and symptoms of exposure, including information on mutagenicity, carcinogenesis, pregnancy safety, and will introduce guidelines for treatment after exposure.

Chest Pain↗

Revision total knee arthroplasty.

BACKGROUND: Revision total knee arthroplasties are performed with increasing frequency due to the increasing numbers of primary arthroplasties. OBJECTIVES: To retrospectively analyze 71 patients who underwent 78 revision total knee arthroplasties during the years 1991 to 1999 METHODS: We evaluated the revised knees using the Knee Society Clinical Rating System after an average follow-up period of 3 years and 9 months (2-10 years). The indications for revision included pain and instability, deep infection of the joint, complaints linked to the patella, or post-trauma to the operated knee. RESULTS: The average knee score (evaluation of the knee joint itself) calculated after the revision was 74.5. The results on the knee score were excellent (> 85) in 48% of patients and poor (< 60) in 22%. The functional results (patient's ability to walk and climb stairs) were only 48.3. CONCLUSION: Although the revision of total knee replacements is known to be problematic, most patients show good results on knee examination, and reasonable functional results given the factors involved.

Aged↗