Biomedical subjects

Shannon J FitzGerald

Publications and source records attributed to Shannon J FitzGerald.

6 recordsLinked to original sources

PubMed2006

Relationships among body composition measures in community-dwelling older women.

OBJECTIVE: To examine whether simple anthropometric measures provide a good estimate of total and visceral fat in 146 community-dwelling, older white women (mean age, 74.0 +/- 4.1 years). RESEARCH METHODS AND PROCEDURES: Total body fat and visceral fat were measured using electron beam computed tomography (EBT). Anthropometric parameters (height, weight, BMI, sagittal diameter, and waist circumference) were measured using standard techniques. Total percentage body fat was assessed using DXA. Spearman correlations were used to examine the association between the measures. Linear regression, controlling for age, was used to examine the associations between the anthropometric parameters and total and visceral body fat measured by EBT. RESULTS: Correlations among body composition measures ranged from rho = 0.46 to 0.93 (p < 0.0001). EBT total fat was strongly correlated with both DXA estimates of total percentage fat (rho = 0.86) and BMI (rho = 0.89). Separate linear regression models indicated that BMI, waist circumference, sagittal diameter, and DXA total percentage fat were each independently related to EBT total fat. BMI had the strongest linear relationship, explaining 80% of the model variance (p < 0.0001). Linear regression indicated that BMI, waist circumference, and sagittal diameter were each independently related to EBT visceral fat, with BMI and sagittal diameter explaining approximately 53% of the model variance (p < 0.0001). DISCUSSION: The use of simple anthropometric measures such as BMI, sagittal diameter, and waist circumference may be an appropriate alternative for more expensive techniques when assessing total fat but should be used with caution when estimating visceral body fat.

Absorptiometry, Photon↗

PubMed2005

Coronary artery calcium score and coronary heart disease events in a large cohort of asymptomatic men and women.

Coronary artery calcium (CAC), a measure of subclinical coronary heart disease (CHD), may be useful in identifying asymptomatic persons at risk of CHD events. The current study included 10,746 adults who were 22-96 years of age, were free of known CHD, and had their CAC quantified by electron-beam tomography at baseline as part of a preventive medical examination at the Cooper Clinic (Dallas, Texas) during 1995-2000. During a mean follow-up of 3.5 years, 81 hard events (CHD death, nonfatal myocardial infarction) and 287 total events (hard events plus coronary revascularization) occurred. Age-adjusted rates (per 1,000 person-years) of hard events were computed according to four CAC categories: no detectable CAC and incremental sex-specific thirds of detectable CAC; these rates were, respectively, 0.4, 1.5, 4.8, and 8.7 (trend p<0.0001) for men and 0.7, 2.3, 3.1, and 6.3 (trend p=0.02) for women. CAC levels also were positively associated with rates of total CHD events for women and men (trend p<0.0001 each). The association between CAC and CHD events remained significant after adjustment for CHD risk factors. CAC was associated with CHD events in persons with no baseline CHD risk factors and in younger (aged <40 years) and older (aged >65 years) study participants. These findings show that CAC is associated with an increased risk of CHD events in asymptomatic women and men.

Adult↗

PubMed2005

Physical activity and decreased risk of clinical gallstone disease among post-menopausal women.

BACKGROUND: Physical activity may play a role in preventing gallstone disease. METHODS: The activity/gallstone relationship was examined in post-menopausal women from the Study of Osteoporotic Fractures (SOF; 1986-1988), a prospective study of fracture risk factors in 8010 women (mean age = 71.1 years, SD = 4.9). RESULTS: Multivariate logistic regression indicated women in the lowest two quartiles of physical activity, according to questionnaire, had a 59% {OR = 1.59 (1.11-2.29), P = 0.02} and a 57% higher risk {OR = 1.57 (1.11-2.23), P = 0.01} of developing gallstone disease compared to women in the highest quartile of activity (PTrend = <0.0001). Additionally, this relationship was examined in a cohort of 182 post-menopausal women (mean age 74.2 years, SD = 4.1) who participated in a randomized controlled trial of a walking intervention. Women in the randomized clinical trial in the lowest tertile of physical activity determined by a physical activity monitor had a higher risk of developing gallstone disease than women in the highest tertile of physical activity, 13% {OR-1.13 (1.01-1.28), P = 0.05, PTrend = <0.04}. CONCLUSION: Physical activity appears to be inversely related to the development of gallstone disease in post-menopausal women independent of body mass index.

Aged↗

PubMed2004

Construct validity of self-reported historical physical activity.

The purpose of this study was to determine the construct-related validity of self-reported historical walking, running, and jogging (WRJ) activity on the basis of data from the Aerobics Center Longitudinal Study (Dallas, Texas). A total of 4,100 men and 963 women underwent at least one medical examination between 1976 and 1985 and completed a follow-up questionnaire in 1986. Levels of glucose, cholesterol, and triglycerides, resting systolic blood pressure, body mass index (weight (kg)/height (m)(2)), and cardiorespiratory fitness were measured at the time of the medical examination. The follow-up questionnaire assessed WRJ and other strenuous activities for each year from 1976 through 1985. Data analysis included Spearman and partial correlations, analysis of variance, analysis of covariance, and t tests. Results indicated significant correlations between recalled WRJ and treadmill times for each year throughout the 10-year period (r = 0.40-0.61). Participants were classified as historically either sufficiently physically active to receive a health benefit or insufficiently active for a health benefit. Engaging in sufficient levels of historical WRJ was associated with higher treadmill times and lower body mass indices for men and women and lower triglyceride levels for men. Self-reported historical WRJ can be assessed with reasonable validity in comparison with measured treadmill performance, with no decay in accuracy of reporting for up to 10 years in the past.

Adolescent↗

PubMed2004

The relationship among physical activity, obesity, and physical function in community-dwelling older women.

BACKGROUND: The relationship between obesity and physical function is not well understood. Physical activity may be a key factor impacting on the relationship between obesity and physical function. METHODS: Subjects included 171 community-dwelling women (mean age = 74.3, SD = 4.3) participating in a 14-year follow-up study to a walking intervention trial. Measures of obesity [body mass index (BMI)] and physical activity (Modified Paffenbarger Questionnaire) were collected in 1982, 1985, 1995, and 1999. Physical function was assessed in 1999 using the Functional Status Questionnaire (FSQ) and gait speed. RESULTS: Measures of obesity from 1982 to 1995 and measures of physical activity from 1982 to 1995 were related to physical function in 1999. However, hierarchical regression analysis to predict physical function in 1999 controlling for the presence of chronic conditions indicated that physical activity from 1982 to 1995, and not obesity from 1982 to 1995, was an independent predictor of physical function (FSQ: adjusted R2 = 0.09, F = 4.68, P < 0.001; gait speed: adjusted R2 = 18.0, F = 9.41, P < 0.0001. CONCLUSION: Physical activity appears to be as important if not more important than body weight in predicting future physical function.

Activities of Daily Living↗

PubMed2004

American adults' knowledge of exercise recommendations.

Physical inactivity is a major risk factor for cardiovascular disease, stroke, hypertension, diabetes, obesity, osteoporosis, and some cancers. Approximately 950,000 Americans die annually from cardiovascular diseases. The purpose of this study was to determine whether American adults know which traditional and lifestyle physical activities affect health and how they should be physically active to achieve a health benefit. Secondary purposes were to determine whether this knowledge is a function of gender, ethnicity, education, or age and if those who are sufficiently active for a health benefit possess different knowledge levels than those not sufficiently active for a health benefit. Items based on the Centers for Disease Control and Prevention/American College of Sports Medicine principles included knowledge of exercise guidelines and traditional and lifestyle physical activities. This information was obtained from 20 questions that were part of a national random telephone survey of 2,002 American households in the 48 contiguous states and the District of Columbia. Respondents were most aware of traditional physical activities (M = 94%) that provide a health benefit and less aware of specific exercise guidelines (M = 68%) and lifestyle physical activities (M = 71%) that can result in a health benefit. Knowledge was not related to physical activity behavior sufficient for a health benefit and only slightly related to ethnicity, education, and age. These data suggest that physical activity knowledge alone is not sufficient to elicit a behavior; however, it provides educators with an understanding of the public's physical activity knowledge that could be helpful in developing health promotion and physical activity interventions.

Adolescent↗