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Biomedical subjects

Shengqi Li

Publications and source records attributed to Shengqi Li.

4 recordsLinked to original sources

Diffuse panbronchiolitis in China.

OBJECTIVE: Diffuse panbronchiolitis (DPB) is a progressive inflammatory disease, well recognized in Japan, that is characterized by chronic sinusitis and obstructive small airway disease. A total of 40 patients with DPB in mainland China were reviewed in order to describe the epidemiology of DPB in China and to compare their clinical characteristics with those of cases reported in Japan. METHODOLOGY: A systematic search was conducted of the Chinese language literature published in mainland China from 1996 to 2003. The 40 subjects who fulfilled the diagnostic criteria for DPB were retrospectively analysed for clinical, physiological, radiological, and pathological features and their geographic distribution. RESULTS: The 40 patients included in this study (31 male and nine female) were distributed in 12 provinces and three other cities in China. All presented with chronic cough, sputum production, and 32 had exertional dyspnoea. All but three had a history of sinusitis. Lung function assessment showed a mixed obstructive-restrictive pattern in 30 cases. CXR revealed diffuse fine nodular shadows in all patients. Human leukocyte antigen-B54 was positive in five patients (n = 12). A total of 30 (75%) patients had been misdiagnosed prior to their diagnosis of DPB being made. CONCLUSIONS: DPB is not rare in China but its incidence is relatively low. Poor recognition and/or genetic factors may be the reason. The clinical, radiographic and histological features of Chinese patients resemble those described in Japanese patients.

Adult↗

[Effect of nutritional state on cardiopulmonary exercise performance in patients with chronic obstructive pulmonary disease].

OBJECTIVE: To explore the effect of nutritional state on cardiopulmonary exercise performance of chronic obstructive pulmonary disease (COPD) patients. METHODS: 43 COPD patients and 20 healthy controls performed incremental cardiopulmonary exercise testing with cycle ergometer. Nutritional assessment and routine lung function studies were performed in all subjects before testing. RESULTS: (1) Compared with the normally nourished COPD group, the malnourished group showed greater reduction in Wmax, VO(2)max, O(2)pulsemax, and AT (P < 0.05), whereas VO(2)/W/V(E) and DImax were higher in the malnourished group (P < 0.05). (2) IBW% was positively correlated with VO(2)max, Wmax, O(2)pulsemax, AT (r = 0.696, 0.432, 0.717, 0.822, P < 0.01), and negatively correlated with DImax and VO(2)/W/V(E) (r = -0.450, -0.640, P < 0.01) in COPD patients. CONCLUSION: Malnutrition adversely affected muscle aerobic capacity and exercise tolerance in COPD patients.

Adult↗

[Epidemiological survey on bronchial asthma in Liaoning province].

OBJECTIVE: To survey the prevalence of asthma in urban and rural residents of Liaoning province in 1999 and evaluate the risk factors for asthma, providing data for research and preventive and therapeutic policies for control of asthma. METHODS: Stratified cluster disproportional random sampling survey was performed in 116 276 residents by common protocols and questionnaire. Asthma was diagnosed based upon case history, clinical signs and lung function tests. Univariate analysis was employed to evaluate the risk factors for asthma. RESULTS: The overall prevalence of asthma in Liaoning province was 1.25%, the male to female ratio being 1:1.64. The prevalence of asthma in adults was 1.39% and that in children was 0.48%. The onset of asthma occurring in children under the age of 14 accounted for 38.63% of the whole patients. The prevalence was higher in peasants, animal breeders and government officials. The prevalence in the rural area (1.89%) was higher than that in the urban area (0.81%) (P < 0.01). The prevalence in Shenyang city (1.66%) was higher than those in Dalian city (0.88%) (P < 0.01) and Jinzhou (0.71%) (P < 0.01) city. Risk factor analysis showed that 24.7% of the asthmatics had family history; 20.4% had allergic history, the OR of allergic rhinitis being 6.28; 26.0% had smoking history; the OR of cooking oil smoke exposure was 5.94. Asthmatic attack was induced by influenza, cold air, irritant gases and cooking oil smoke in 52.3% approximately 63.3% of the patients. Asthma induced by exercising, fatigue, emotion and allergy was found in more than 41.3% of the patients. CONCLUSIONS: Our epidemiologic data reflected the general distribution of asthma in Liaoning province. From the overall prevalence rate, it is estimated that there are about 529 700 asthmatics in the whole province. The data will be helpful for the mass prevention and treatment of asthma.

Adolescent↗