Biomedical subjects

Shinji Akishima

Publications and source records attributed to Shinji Akishima.

2 recordsLinked to original sources

PubMed2004

[Stickler syndrome with rapidly progressive mitral valve regurgitation: report of a case].

A 36-year-old man with Stickler syndrome who underwent mitral valve replacement for rapidly progressive mitral regurgitation due to prolapse of an anterior leaflet. Stickler syndrome is a relatively rare condition caused by a defective collagen gene and characterized by high myopia, sensorineural-hearing deficit and flattened facial features. The prevalence of mitral valve prolapse in Stickler syndrome is reported to be much higher than in the general population because of its connective tissue dysplasia. Mitral regurgitation rapidly and refractorily progresses. Prompt surgical treatment should be recommended to mitral regurgitation in Stickler syndrome, and mitral valve replacement with a prosthetic valve is a better selection than mitral valve plasty for tissue fragility.

Adolescent↗

PubMed2003

Complex intimal flaps in acute aortic dissection.

A 43-year-old man was emergently admitted and diagnosed as acute aortic dissection (Stanford type A). While being prepared for emergent operation he fell into hemodynamic hazard with repeated ventricular fibrillation and loss of consciousness. Massive aortic regurgitation and coronary disturbance due to a back-and-forth movement of an intimal flap through the aortic valve were the causes of the cardiogenic catastrophy. In addition, a completely torn intimal flap was intussuscepted into the origin of the brachiocephalic artery. This was thought to disturb the cerebral perfusion. Acute aortic dissection with such complex intimal flaps is very rare. In such cases cardiopulmonary bypass should be established to maintain the patient's cardiac function as soon as possible after diagnosis and the operation should be performed with sufficient brain protection.

Acute Disease↗