Biomedical subjects

Shuqin Yang

Publications and source records attributed to Shuqin Yang.

2 recordsLinked to original sources

PubMed2006

Intraclass correlation coefficients and bootstrap methods of hierarchical binary outcomes.

Intraclass correlation coefficients are designed to assess consistency or conformity between two or more quantitative measurements. When multistage cluster sampling is implemented, no methods are readily available to estimate intraclass correlations of binomial-distributed outcomes within a cluster. Because statistical distribution of the intraclass correlation coefficients could be complicated or unspecified, we propose using a bootstrap method to estimate the standard error and confidence interval within the framework of a multilevel generalized linear model. We compared the results derived from a parametric bootstrap method with those from a non-parametric bootstrap method and found that the non-parametric method is more robust. For non-parametric bootstrap sampling, we showed that the effectiveness of sampling on the highest level is greater than that on lower levels; to illustrate the effectiveness, we analyse survey data in China and do simulation studies.

Biometry↗

PubMed2002

[Effect of nutritional state on cardiopulmonary exercise performance in patients with chronic obstructive pulmonary disease].

OBJECTIVE: To explore the effect of nutritional state on cardiopulmonary exercise performance of chronic obstructive pulmonary disease (COPD) patients. METHODS: 43 COPD patients and 20 healthy controls performed incremental cardiopulmonary exercise testing with cycle ergometer. Nutritional assessment and routine lung function studies were performed in all subjects before testing. RESULTS: (1) Compared with the normally nourished COPD group, the malnourished group showed greater reduction in Wmax, VO(2)max, O(2)pulsemax, and AT (P < 0.05), whereas VO(2)/W/V(E) and DImax were higher in the malnourished group (P < 0.05). (2) IBW% was positively correlated with VO(2)max, Wmax, O(2)pulsemax, AT (r = 0.696, 0.432, 0.717, 0.822, P < 0.01), and negatively correlated with DImax and VO(2)/W/V(E) (r = -0.450, -0.640, P < 0.01) in COPD patients. CONCLUSION: Malnutrition adversely affected muscle aerobic capacity and exercise tolerance in COPD patients.

Adult↗