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Biomedical subjects

Sigrid Hørven Wigers

Publications and source records attributed to Sigrid Hørven Wigers.

2 recordsLinked to original sources
PubMed2004

Depressed mood impedes pain treatment response in patients with fibromyalgia.

OBJECTIVE: To investigate prognostic factors in the course of the fibromyalgia syndrome (FM) from baseline to post-treatment. METHODS: Fifty-seven patients with FM were examined in a randomized intervention study. Pre-treatment variables were entered into linear regression analyses: gender, age, duration of disease, allocation to treatment, pain distribution (based on a patient-made drawing), fatigue, sleep disturbance, and depressed mood (based on visual analog scores), with pain distribution at treatment completion as the dependent variable. RESULTS: Depressed mood at baseline was a significant predictor of sustained widespread pain at treatment completion. CONCLUSION: The findings indicate a role for depressed mood as a predictive factor for treatment response.

Adult↗
PubMed2002

[Fibromyalgia--an update].

BACKGROUND: Fibromyalgia is a common, female dominated condition, characterized by chronic widespread pain, fatigue, sleep disturbance, anxiety/depression and a number of other symptoms. The syndrome's aetiology and treatment is disputed. However, research over the last decade has provided substantial new information. MATERIAL AND METHODS: This review is an update on fibromyalgia with respect to predictors, pathogenesis and treatment. On the basis of a number of important scientific publications, the most relevant theory is presented and discussed. RESULTS: Fibromyalgia may be described as a biopsychosocial disorder in which long lasting distress, myofascial pain, central sensitisation, sickness behaviour, anxiety/depression, neuroendocrine and autonomic dysfunction play central aetiological roles as elements in a vicious circle. Treatment should be focused on each of these elements and requires active patient participation. It is best given as a multidimensional, multidisciplinary rehabilitation programme with continuous support from the general practitioner. INTERPRETATION: Even though the fibromyalgia riddle is not yet fully solved, research over the last decade has given valuable new information on pathogenesis and treatment. We should be able to offer our patients substantial help on the basis of present knowledge.

Diagnosis, Differential↗