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Biomedical subjects

Silvia Hohenleutner

Publications and source records attributed to Silvia Hohenleutner.

7 recordsLinked to original sources

Results of nonablative wrinkle reduction with a 1,450-nm diode laser: difficulties in the assessment of "subtle changes".

BACKGROUND AND OBJECTIVE: Nonablative resurfacing has proven its efficacy in vascular and pigmented lesions, while its capacity of substantial wrinkle reduction is still discussed controversially. We present the treatment results of a 1,450 nm diode laser for facial rhytides. METHODS: Thirty facial regions were treated with a 1,450 nm diode laser. Pre- and post treatment pictures were compared by the treating physician and two blinded observers. RESULTS: Even if mild improvement was rated in up to 35% of the post treatment pictures, a discrepancy shows up in the assessments of the three observers, presenting almost no congruency in the rating of improvement. CONCLUSIONS: Our study failed to provide convincing data on the efficacy of nonablative treatment of rhytides with the 1,450 nm diode laser. In this respect, we challenge objective judgment in the assessment of subtle changes in nonablative wrinkle reduction.

Adult↗

Comparison of two absorbable monofilament polydioxanone threads in intradermal buried sutures.

BACKGROUND AND OBJECTIVES: Two absorbable polydioxanone threads are compared regarding intraoperative handling qualities, scar dehiscence, and possible side effects. METHODS: In 30 excisions, half of each suture was performed with PDS II (Ethicon GmbH, Norderstedt, Germany), whereas the other half was closed with Serasynth (Serag-Wiessner, Naila, Germany). Clinical evaluation for scar spreading, spitting of the sutures, hypertrophic scarring, or suture granuloma was performed 3 and 6 months after surgery. RESULTS: No significant difference in scar spreading, hypertrophic scarring, or the incidence of suture granuloma was noted. A significantly lower frequency of spitting was seen with Serasynth than with PDS. The handling and suturing properties of SerasynthM were estimated to be slightly superior compared with those of PDS. CONCLUSION: Our study shows that PDS and Serasynth provide equal cosmetic results when applied in an appropriate suturing technique. Possibly owing to its better pliability, the frequency of spitting was lower with Serasynth.

Absorbable Implants↗

Early recurrence of eruptive vellus hair cysts after Er:YAG laser therapy: case report and review of the literature.

BACKGROUND: Therapy of eruptive vellus hair cysts (EVHCs) often leads to unsatisfying results or recurrences. Recently, erbium:yttrium-aluminum-garnet (Er:YAG) laser therapy has been recommended in this condition. OBJECTIVE: To report the results of Er:YAG laser treatment and discuss the treatment options in EVHC, presenting a review of the literature. METHODS: Full-face Er:YAG laser therapy was performed in a 30-year-old female patient with a 15-year history of cosmetically bothersome facial EVHCs. RESULTS: Immediately after the laser treatment, the ablated skin showed an even surface, presenting no residual signs of EVHCs. After reepithelialization, however, early recurrence of EVHCs occurred. Recurrence was also observed in the previously treated test spot, where slight atrophy indicated deeper ablation. CONCLUSION: Er:YAG laser therapy might be a treatment option for distinct lesions of EVHCs but proved to be ineffective in a case of EVHCs in the face, where the depth of ablation is limited owing to the risk of atrophy or scarring and where deep enucleation of distinct single cysts was not possible owing to the dense dissemination of the lesions. Despite numerous treatment options reported in the literature, therapy for EVHCs is still challenging owing to recurrences or side effects.

Adult↗

[The "red melanoma"--a rare form of amelanotic malignant melanoma].

The two major variants of amelanotic malignant melanoma are the verrucous and the polypoid forms. A further--albeit rare--red eczematous variety has also been described. We report two female patients with reddish, non-pigmented, scaly lesions on the upper arm and the shoulder that had developed 2 to 3 years previously. One biopsy showed the diagnosis of a melanoma growing in situ while the second revealed a highly atypical melanocytic tumour. However, the histopathological examination of the entire tumour showed a superficial spreading amelanotic malignant melanoma. Therefore, in non-healing erythematous lesions, even without pigmentation or ulceration, the rare differential diagnosis of amelanotic malignant melanoma should be taken in consideration and a biopsy should be performed prior to therapy without histological control.

Aged↗

Spindle cell hemangioma.

BACKGROUND: Spindle cell hemangioma (SCH) is an uncommon benign vascular tumor. OBJECTIVE: To report and discuss a case of SCH in an 11-year-old boy. METHODS: A case report and discussion of the rare entity of SCH are given. RESULTS: The excision of a vascular tumor showed a vascular connection to the great saphenous vein. Histologic examination was consistent with SCH. CONCLUSION: The diagnosis of SCH is supported by typical histologic and immunohistochemical features and by the intraoperative finding of an association with a large vessel.

Child↗