Biomedical subjects

Sinisa Stojić

Publications and source records attributed to Sinisa Stojić.

4 recordsLinked to original sources

PubMedDate not supplied

[Oral health in pregnancy].

INTRODUCTION: Good oral health care during pregnancy is essential but often overlooked factor of dental growth as well as of other structures of oral cavity. Pregnancy is the time when conscious approach to preventive oral care should increase. PREVENTIVE MEASURES DURING PREGNANCY: Preventive measures during pregnancy mean usage of fluorides, special dietary measures and increased oral hygiene habits. Preventive measures in pregnant women have one goal: providing conditions for development of fetal teeth as well as preventing tooth decay in pregnant women. The optimal period for introducing preventive measures is the first trimester of pregnancy. ALTERATIONS OF ORAL HEALTH DURING PREGNANCY: Because of hormonal alterations there is an increased incidence of dental diseases: gingivitis and low salivary pH (inflammation and bleeding gums). IMPACT OF NUTRITION DURING PREGNANCY ON ORAL HEALTH: Eating habits of pregnant women may lead to frequent snacking on candy or other decay-promoting foods, thereby increasing the risk of caries. However, very poor oral health, possible dental complications and their consequences to the health as well as emotional status represent very strong reasons for activation of dental health care in this period.

Dental Care↗

PubMedDate not supplied

[Amnionic infusion therapy in conditions with low amnionic fluid levels].

INTRODUCTION: Amniotic fluid volume reduction can have serious consequences: prior to 24 gestational weeks hypoplasia of fetal lungs and later in pregnancy cord compression and fetal hypoxia as well as contractions of extremities. Diagnosis of oligohydramnios is made either after a subjective estimation of amniotic fluid reduction or if the biggest amniotic fluid pocket is less than 1 cm. Amnioinfusion is a procedure during which a crystalloid solution, most often saline, is instilled into the amniotic cavity substituting amniotic fluid. To estimate the efficacy and safety of amnioinsfusion using our results and literature review. MATERIAL AND METHODS: Up to 800 ml of sterile saline solution was instilled intraamniotically (10-15 ml/min) in cases where the amniotic fluid index was less than 10 and intraamniotic infection was excluded. After that, 1 g of Longaceph was given intraamniotically. Infusion was stopped immediately when 800 ml was instilled, if a subjective estimation showed that there was enough fluid or if contractions occurred. RESULTS: During a six-month period there were five amnioinfusions--four therapeutical and one diagnostic; in four cases the procedure was successful and in one preterm rupture of membranes occurred 20 hours after the procedure. The procedure was most often done in the first half of the third trimester and continuation of pregnancy in successful cases was between 4 and 5 weeks, with average fetal weight gain of about 1200 gr. No complications occurred in cases where pregnancy continued. CONCLUSION: In our preliminary study amnioinfusion led to prolongation of pregnancy in majority of cases providing better maturation of fetal lungs and higher birth weight, without any complications. Further studies are necessary to reach definite conclusions about the efficacy and safety of amnioinfusion.

Crystalloid Solutions↗

PubMedDate not supplied

A longitudinal follow-up of cervical length during pregnancy.

A prospective longitudinal study of cervical length during pregnancy included 60 women. Three groups of patients were analyzed: group I--cervical length was measured in all three trimesters, group II--cervical length was measured in the first and second trimesters, and group III--length was measured in the second and third trimesters. Cervical length was measured in each group individually, with the aim of establishing the trend of change. In the group in which the cervical length was measured in all three timesters, there was either a mild progressive cervical shortening or cervix remained of the same length. The number of examined women is very small, though, so more valid is the information that the trend of mild shortening occurs in the second and third trimesters. None of the trends is particulary explicit and shows that there is a period in an uncomplicated singleton pregnancy of low risk for preterm delivery, during which there is a significant shortening before delivery takes place. During pregnancy there are different, individual modes of cervical changes, which leads to individualization when estimating the risk for preterm delivery. Reference values should be established for cervical length in order to assess risk for preterm delivery, rather than use the "cut-off" value after which the risk is considered higher.

Cervix Uteri↗

PubMedDate not supplied

[Amnioreduction in treatment of increased amniotic fluid volume].

INTRODUCTION: Increased amniotic fluid volume may significantly increase the risk for preterm delivery. Amniodrainage is a symptomatic treatment by which excess amniotic fluid is reduced to provide fetal lung maturation. The aim of this stuldy is to estimate the efficacy and safety of this procedure, our results and give a literature review. MATERIAL AND METHODS: Sonografic criteria were used (AFI >400 ml, or the biggest amniotic fluid pocket >150 mm) to choose patients in whom 18G needle was used to allow leaking of excessive amniotic fluid. RESULTS: 10 patients underwent 26 procedures. The procedures were performed at 28.6 th week gestation, on average and 6.25 weeks average gain or 1000 g. We had two sets of monochorionic twins with twin-to-twin transfusion syndronme (TTTS), where one child survived. One procedure was followed by premature placental abruption, and premature delivery in 28th week. The rest of procedures were uneventful. CONCLUSION: In our series of 10 women, 26 procedures were performed to prolong pregnancies, enable fetal maturation and weight gain. In majority of cases amnioreduction was done without complications, so we could repeat the intervention and prolong the pregnancy. Survival of one child in two TTTS pregnancies should not be regarded unsulccessful in our conditions.

Amniotic Fluid↗