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Biomedical subjects

Slobodanka Djukić

Publications and source records attributed to Slobodanka Djukić.

6 recordsLinked to original sources

Surgical wound infection associated with Psychrobacter phenylpyruvicus-like organism.

A case of surgical wound infection caused by Psychrobacter phenylpyruvicus-like organism is described. The strain showed phenotypic characteristics typical of P. phenylpyruvicus, but 16S rRNA sequencing showed 98.2% relatedness to Moraxella phenylpyruvica strain 752/52 and only 94.8% with P. phenylpyruvicus type strain ATCC 23333(T). The results of molecular analysis suggest that the strain we isolated may represent a new species within the genus Psychrobacter.

Aged↗

Antimicrobial activity of human follicular fluids.

The aim of this study was to explore the antimicrobial activity of human follicular fluid (HFF), to test the hypothesis that different strains of the same bacterial species could display different patterns of susceptibility to antimicrobial action of HFF, and to preliminarily investigate the possible mechanism of antimicrobial action of this fluid. Antimicrobial activity of 60 samples of HFF toward 30 Streptococcus agalactiae strains was determined by the agar diffusion method and broth dilution method. To explore the mechanism of antimicrobial activity, biochemical analyses were performed with selected fluid samples. The obtained results indicate that 38.3% fluid samples did not inhibit bacterial growth, 53.3% showed moderate and 8.3% high antimicrobial activity. The tested effect of HFF on S. agalactiae strains was bactericidal and was not strain dependent. Lysozyme activity was detected in HFF exhibiting antimicrobial activity. There were no statistically significant differences in concentrations of estradiol, progesterone, transferrin, iron, total protein and albumin levels among tested samples regardless of the different rate of antimicrobial activity. The obtained results indicate that lysozyme is most probably a crucial antibacterial agent in this fluid; however, some other still unidentified factors may contribute to it.

Anti-Bacterial Agents↗

Surgical wound infection associated with Staphylococcus sciuri.

We describe a case of surgical wound infection due to Staphylococcus sciuri. The isolated strain was susceptible to trimethoprim-sulfamethoxazole, erythromycin, chloramphenicol, ciprofloxacin and vancomycin and resistant to gentamicin, clindamycin, rifampicin, methicillin, ampicillin and ceftriaxone. The multiresistance of the strain had a serious impact on the prolonged course of the infection. Although this bacterium is principally found in animals, our strain was probably of nosocomial origin.

Anti-Bacterial Agents↗