Biomedical subjects

Solmaz Ozalp

Publications and source records attributed to Solmaz Ozalp.

4 recordsLinked to original sources

PubMed2005

Lepromatous iridocyclitis.

A 36-year-old woman with no prior medical history presented with a unilateral decrease in vision and iridocyclitis to our hospital. External examination demonstrated multifocal, firm, elevated, non-tender skin nodules on the patient's face and left hand. In addition, slit-lamp biomicroscopy revealed gray, cheesy-appearing nodules on the iris surface of the affected eye. Anterior chamber paracentesis and pars plana vitrectomy did not reveal further information. Skin nodule biopsy, however, demonstrated multiple fragmented organisms within histiocytes, consistent with leprosy. The iridocyclitis resolved after treatment with dapsone, corticosteroids, and rifampin and her vision returned to 20/20.

Adult↗

PubMed2004

Optic atrophy and macular degeneration as initial presentations of subacute sclerosing panencephalitis.

PURPOSE: To report a case of subacute sclerosing panencephalitis in which the initial clinical presentations were optic atrophy and macular degeneration. DESIGN: Observational case report. METHODS: A 9-year-old boy with visual loss attributable to optic atrophy and macular degeneration had a diagnostic examination. RESULTS: The visual acuity levels of both eyes were light perception at presentation. Fundus examination revealed bilateral optic atrophy and macular degenerative changes including retinal pigment epithelial atrophy, macular scarring, and epiretinal membrane formation. The antimeasles IgG titers were high both in serum and cerebrospinal fluid samples. Neurologic symptoms of myoclonus, ataxia, motor, and mental disabilities occurred 4 months after the onset of first visual disturbances and 2 weeks after the patient applied to our clinic. CONCLUSION: Children with optic atrophy and macular degenerative lesions should be examined for sclerosing panencephalitis, even if the classical neurologic symptoms of this disease are not present.

Analgesics, Non-Narcotic↗

PubMedDate not supplied

Subclinical optic neuropathy in Graves' orbitopathy.

PURPOSE: The aims of the study were to detect early changes in the optic nerve function of patients with Graves' orbitopathy (GrO) who do not have any signs and symptoms of optic neuropathy, using pattern visual evoked potentials (P-VEP), and investigate any possible relation between the disease activity and P-VEP P100 latencies of the patient group. METHODS: The study was conducted in a tertiary care hospital. Sixteen patients with GrO and 15 healthy controls were enrolled. P-VEP P-100 latencies were compared between these two groups. Correlation between the clinical disease activity and P-VEP P-100 latencies of the patient group was also investigated. RESULTS: Mean P-VEP P-100 latency values were significantly different in the GrO (122.0+/-14.40 ms) and control groups (105.9+/-7.7 ms) (P=.0004). The GrO patients' P-100 latencies correlated mildly with their activity scores (r=.364, P=.0406). CONCLUSIONS: Clinical application of the P-VEP for the assessment of visual function in patients with GrO proved useful for early diagnosis of the optic nerve involvement, and it may be more valuable in patients with "active" congestive disease.

Adult↗

PubMedDate not supplied

Traumatic optic nerve avulsion.

A 10-year-old boy presented with optic nerve avulsion associated with ptosis and limitation of elevation and adduction secondary to blunt ocular trauma. At the initial examination the funduscopic view was hazy because of concurrent vitreous hemorrhage. Ultrasonography revealed a posterior ocular wall defect and a hypolucent area in the region of the optic nerve head.

Child↗