Biomedical subjects

Song-Liang Cai

Publications and source records attributed to Song-Liang Cai.

6 recordsLinked to original sources

PubMed2006

[Diagnosis and treatment of priapism due to neoplasma of penis].

OBJECTIVE: To improve the clinician's ability for emergency treatment of priapism. METHODS: Both cases received 2 mg to 8 mg of metaraminol injection at the root of cavernous body, and perfusion of heparinized saline at glans and root of cavernous body of the penis by contrecoup, but they had not good response to the above therapy. At last surgery was performed. RESULTS: Total penectomy was performed for both cases. One case was diagnosed of penile sarcoma, and another was metastatic transitional cell carcinoma. CONCLUSION: Priapism due to neoplasma is infrequent, it should not be misdiagnosed in case of emergency.

Erectile Dysfunction↗

PubMed2006

[Distribution features of Gleason score and its relationship with clinical stages in 346 prostate cancer patients].

OBJECTIVE: To analyze the distribution features of Gleason score and evaluate the relationship between Gleason score and clinical stages in patients with prostate cancer. METHODS: Surveys were made of the inpatients with prostate cancer diagnosed by pathology from January 1992 to June 2005 in our hospital. Gleason score and clinical stages were determined on the basis of pathological examination and clinical data of the prostate cancer patients. The patients were divided into three groups (1992-1999, 2000-2002 and 2003-2005). The Chi-square test was used to evaluate the distribution and differences of Gleason score among the three groups. Spearman rank correlation was applied to the evaluation of the relationship between Gleason score and clinical stages. RESULTS: We found a statistically significant shift in the distribution of Gleason score (chi2 = 17.703, P < 0.01), and a slight increase in the mean Gleason score. The proportion of moderately differentiated tumor increased (chi2 = 10.736, P < 0.01). There was little change in the proportion of Gleason score 7, 8, 9 and 10 (chi2 = 4.038, P > 0.05). Gleason score had a significant positive correlation with clinical stages in the 346 cases of prostate cancer (r = 0.452, P < 0.01). Significant difference was observed between Gleason score 2-6 and 7 or 8-10 (chi2 = 8.786, P < 0.01, chi2 = 22.956, P < 0.01), but not between the latter 2 groups (chi2 = 0.787, P > 0.05) in prediction of organ-confined disease. CONCLUSIONS: Gleason score 7 shows the similar value to Gleason score 8-10 in predicting the progression of the disease. Gleason score was significantly correlated with clinical stages, which suggests that Gleason score is also an important indicator for the prognosis of prostate cancer.

Adult↗

PubMed2005

[Age and pathological features of 481 prostate cancer patients].

OBJECTIVE: To investigate the age and pathological features of prostate cancer patients in recent years. METHODS: An analysis was made of the age and pathological features of 481 cases of prostate cancer pathologically diagnosed from January 1998 to April 2004, 39 cases in 1998, 69 in 1999, 73 in 2000, 68 in 2001, 72 in 2002, 121 in 2003, and 39 in the first four months of 2004. RESULTS: The patients ranged in age from 40 to 91 years, averaging 72, 95% between 55 and 84, and 84.2% over 65 years. Pathologically, 14 cases were well, 29 moderately, and 83 poorly differentiated according to the three-grade system (WHO, the Mostofi system), with 355 cases ungraded. Forty cases (8.3%) were microcarcinoma (< 1 cm), and 20 cases (4.2%) incidental carcinoma. Of the total number, 473 cases (98.1%) were pathologically diagnosed as adenocarcinoma, 1 endometrioid adenocarcinoma, 1 squamous cell carcinoma, 1 signet ring cell carcinoma, 1 adenosquamous cell carcinoma, 1 small cell carcinoma, 1 mucinous adenocarcinoma, 1 adenoid cystic carcinoma, and 1 transitional cell carcinoma. CONCLUSION: Prostate cancer commonly develops in men over 65 years, and adenocarcinoma is the most common histological type. The disease has become a major malignant tumor to endanger elderly males.

Adenocarcinoma↗

PubMed2005

[Diagnosis and treatment of urinary neurofibrosarcoma].

OBJECTIVE: To investigate the clinical characteristics, diagnosis and treatment of urinary neurofibrosarcoma. METHODS: Clinical data of 1 case of urinary neurofibrosarcoma was analyzed retrospectively and related literature reviewed. The 61-year old male patient had undergone TURP for benign prostate hyperplasia ten months before. RESULTS: Total urethral cavernostomy, total cystectomy and ileal cystostomy were performed on the patient and pathological diagnosis pointed to urinary neurofibrosarcoma. Another operation was done for metastatic rectal mass, which revealed abdominal metastasis. With progressing consumptive constitution, the patient died 40 days after the second operation. CONCLUSION: It is difficult to make a definite diagnosis in urinary neurofibrosarcoma, and the effective treatment for this highly malignant disease needs to be further studied.

Humans↗

PubMed2003

[Diagnosis of the testicular tumor (57 case reports)].

OBJECTIVE: To improve the diagnosis of the testicular tumor. METHODS: Fifty-seven cases, including their signs and symptoms, imaging studies, tumor markers and histologic diagnoses, were reviewed. RESULTS: 31.3% of the patients failed to go to hospital in time. B mode ultrasound and CDFI had sensitivity of 93.5% and 96.4% respectively. Compared with final diagnoses, 23 from 26 cases (88.5%) were correspondingly diagnosed by intraoperative frozen section examination (FSE), which, however, had no definitive influence on the surgical management. Histologic examination showed 22 patients with seminoma, 9 with embryonal carcinoma, 7 with teratoma, 3 with yolk sac tumor, 9 with combined patterns, 4 with lymphoma, and 3 with other histologic types of tumor. CONCLUSIONS: For earlier diagnosis, patients testicular self-examination counts for much, and ultrasound and CT should be used before possible histologic examination, while all patients with testicular tumors should have intraoperative FSE, which is very practical in identifying malignant and benign masses, and in choosing between enucleation of the tumor and radical orchiectomy.

Adolescent↗

PubMed2002

[A comparative study of computer assistant sperm analysis with rontine sperm analysis]

OBJECTIVE: To compare computer assisted sperm analysis (CASA) with routine sperm analysis (RSA) in evaluation of male fertility. METHODS: The results of CASA were compared with the RSA of 27 males normal fertility and 317 males with infertility. RESULTS: Using the CASA, deformity rate was lower than RSA, it was 25.10+/-8.57 and 31.48+/-12.81 in the fertile and infertile groups respectively, whereas, RSA was 35.56+/-9.58 and 54.56+/-13.47. Fertile group motility had a significant difference, it was 61.35+/-7.62 and 83.96+/-6.67. Sperm vitality of grades A was 9.10+/-5.50 and 30.33+/-8.85. The vitality of grades B was 31.16+/- 12.35 and 49.93+/-8.56, the vitality of grades C awas 21.06 +/-14.19,and 3.70+/-2.12, the vitality of grades D was 38.66+/-7.62 and 16.04+/-6.67. When two techniques were adopted, the mobility had no difference in infertile group (42.53+/-14.95 and 43.09+/-13.96), the sperm vitality was decreased in grades B (CASA 22.67+/-14.96,RSA 33.32+/-13.47), increased in grades C(CASA 17.08+/-13.47,RSA 7.68+/-5.82), they had significant differences (P<0.01). The grade B sperms in the non-forward moving group, CASA was 2.77+/-6.01, RSA 0. In addition, VSL, VCL, VAP, ALH, sperm trace and static diagram were adopted. CONCLUSION: Using the CASA,the distinguished ability to sperm shape and vigor was lower than RSA, but the quantize marker (such as straight line velocity, curved velocity, average path velocity and ALH) and moving, static images could reflect on sperms quality more objectively.

Journal Article↗