Biomedical subjects

Soo Kyung Han

Publications and source records attributed to Soo Kyung Han.

4 recordsLinked to original sources

PubMed2005

Effect of basic fibroblast growth factor on fibrovascular ingrowth into porous polyethylene anophthalmic socket implants.

To investigate the effect of basic Fibroblast Growth Factor (bFGF) on fibrovascular ingrowth into porous polyethylene orbital implants (Medpor) and to investigate any differences according to the method of administration. For the treated groups, after evisceration and Medpor implantation, bFGF was administered by soaking Medpor in the bFGF solution, and/or by injecting bFGF into the Medpor 1 week after the operation. Implants were removed 4 weeks after the operation and examined for the degrees of fibrovascular ingrowth by light microscopy. The percentages of the cross-sectional area of the implant occupied by fibrovascular ingrowth and the numbers of proliferated vessels were significantly higher in the bFGF-treated groups (Mann Whitney test, p<0.05). Administration routes had no effect on the degree of fibrovascular ingrowth (Kruskal-Wallis test, p>0.05). bFGF promoted fibrovascular ingrowth into porous polyethylene orbital implants regardless of the route of administration. Therefore, bFGF might be helpful to prevent complications such as implant exposure.

Animals↗

PubMed2004

Persistent diplopia after retrobulbar anesthesia.

PURPOSE: To determine the causative factors of persistent diplopia after retrobulbar anesthesia. SETTING: Strabismus Section, Department of Ophthalmology, Seoul National University, Seoul, South Korea. METHODS: Prism and alternate cover tests in the diagnostic positions of gaze and ductions/versions were performed in 28 patients with persistent diplopia 6 months after retrobulbar anesthesia. The Lancaster test, Bielshowsky head tilt test, double Maddox rod test, fundoscopic examination for torsion, forced duction test, force generation test, tensilon test, thyroid function test, and/or orbit computed tomography were performed when necessary. RESULTS: Most of the patients (26 patients, 93%) did not have diplopia before retrobulbar anesthesia. Of the 14 patients with extraocular muscles imbalance, 12 patients showed vertical rectus overaction (11 superior recti, 1 inferior rectus) and 2 patients, mild vertical rectus underaction. Nine patients were presumed to have a sensory strabismus related to the preoperative poor vision, but this went unnoticed preoperatively. Three patients showed a small vertical deviation without any specific causative factors. CONCLUSIONS: Fifty percent of the cases of diplopia were associated with either direct trauma or anesthetic myotoxicity to the extraocular muscles, in which overactions were more common than underactions. Thirty-two percent of the patients were presumed to have sensory strabismus, which suggested the importance of preoperative examination for strabismus as well as providing an explanation about the risk of postoperative diplopia before surgery.

Adult↗

PubMed2003

Thyroid disease and vertical rectus muscle overaction after retrobulbar anesthesia.

PURPOSE: To determine the associated factors of persistent diplopia after retrobulbar anesthesia. SETTING: Strabismus Section, Department of Ophthalmology, Seoul Municipal Boramae Hospital, Seoul, Korea. METHODS: A prism and cover test in the diagnostic positions of gaze, force-generation test, and forced-duction test were performed in 11 patients with vertical rectus overaction after retrobulbar anesthesia. A Tensilon (edrophonium chloride) test, thyroid function test, and orbit computed tomography were performed in 8 patients. RESULTS: None of the 11 patients reported diplopia before receiving local anesthesia. Ten patients showed ipsilateral hypertropia with superior rectus overaction and 1 patient, ipsilateral hypotropia with inferior rectus overaction. One patient had partial fibrosis of the medial half of the superior rectus, presumably caused by a bridle suture. Four (50%) of 8 patients in whom a thyroid function test was performed had abnormal findings; 1 had a history of systemic dysthyroidism. CONCLUSIONS: In this study, permanent vertical strabismus after local anesthesia was entirely the result of overactive vertical rectus muscles, mostly the superior rectus muscle. Half the patients who had a thyroid function study had abnormal findings.

Adult↗

PubMedDate not supplied

Retroscleral implantation technique for porous polyethylene orbital implant after evisceration.

The authors developed a technique for the retroscleral implantation of a porous polyethylene orbital implant after evisceration for the placement of an adequately large orbital implant without wound tension. The surgical results of the technique in 27 patients are reported. The technique involves the severance of the optic nerve after standard evisceration and the insertion of the orbital implant into the retroscleral and intraconal space through the side of the scleral shell. All patients received a 20-mm orbital implant. No complications such as infection, implant exposure, or worsened implant motility were observed during the average follow-up period of 22.4 months. Retroscleral implantation of the orbital implant after evisceration may be an appropriate procedure that allows placement of a large orbital implant without exposure or decreased implant motility.

Adolescent↗