Biomedical subjects

Soumaya Rammeh

Publications and source records attributed to Soumaya Rammeh.

4 recordsLinked to original sources

PubMed2005

[A particular hepatocellular carcinoma combining the ordinary and the fibrolamellar variant].

Fibrolamellar carcinoma (FLC) of the liver is a rare variant of hepatocellular carcinoma (HCC) occurring on non cirrhotic liver. Since its first description by Hugh Edmondson in 1956, 200 cases of FLC have been reported in the literature, but only some cases describe the association of the ordinary HCC with the FLC within the same lesion. We report in this study the case of a 14-year-old female patient with a hepatic mass whose radiological aspect evoked a nodular and focal hyperplasia. Histologically, this tumor was composed of area of FLC mixed with ordinary HCC. Staining for cytokeratine 7 was positive in the FL component and negative in the ordinary HCC component.

Adolescent↗

PubMed2005

[Retroperitoneal Castleman disease].

Castleman disease or angiofollicular lymph node hyperplasia is a rare disease of unknown cause with polymorphic clinical features that raises many diagnostic and therapeutic problems. The unifocal, localized, pseudoneoplastic form, first described in 1956, has a good prognosis, but the multifocal form has a more aggressive course. Three histological types have been identified: hyaline vascular, plasma cell and mixed. The authors present a case of hyaline vascular unifocal Castleman disease. A retroperitoneal mass was discovered incidentally during follow-up ultrasound examination in a 38-year-old woman treated for recurrent renal stones. On CT examination, a solid mass measuring 9 x 8 x 6 cm raised a problem of differential diagnosis with other retroperitoneal masses. CT-guided biopsy was inconclusive and the diagnosis was finally established by tumour excision and histological examination. The immediate and subsequent postoperative course was uneventful.

Adult↗

PubMed2003

[Intra-abdominal desmoplastic small round cell tumor in childhood: case report and review of the literature].

Desmoplastic small round cell tumor (DSRCT) correspond to a recent clinicopathological entity, individualized in 1989 into the group of tumors with small round cells. This pathology puts ethiopathogenic, diagnostic, therapeutic and prognosis problems. Indeed, the ethiopathogenic is still unknown, diagnosis is asserted only by immuno-histochimic and cytogenetic study because of the big number of differential diagnoses and the anatomopathologic polymorphism. Its treatment is not well codified and its outcome remains dark in spite of therapeutic progress. The objective of this work is to report a personal observation of a DSRCT and to proceed to a review of the literature to clarify the epidemiological, clinical, paraclinical and therapeutic aspects of this rare tumor.

Abdominal Neoplasms↗

PubMed2002

[Epstein-Barr virus in Hodgkin's disease: the example of central Tunisia].

The purpose of this study was to evaluate the prevalence of Epstein-Barr virus in Hodgkin disease in Tunisia through a series of 77 cases. Association with Epstein-Barr virus was demonstrated by Epstein-Barr encoded early RNA transcripts (EBER) in situ hybridization in 70% of cases and by latent membrane protein 1 (LMP1) immunohistochemistry in 58.4% of cases. EBER positive cases were more frequent in extreme age classes (<15 and>54 years) there was no correlation with sex, histologic sub-type and clinical stage. Our findings show a high prevalence for EBV infection in Tunisian Hodgkin's disease particularly among extreme ages.

Adolescent↗