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Stanley Goldfarb

Publications and source records attributed to Stanley Goldfarb.

4 recordsLinked to original sources
PubMed2006

Contrast-induced nephropathy: how it develops, how to prevent it.

No current treatment can reverse or ameliorate contrast-induced nephropathy once it occurs, but prophylaxis is possible. Many preventive measures have failed to show benefits in well-designed, prospective, randomized, double-blinded trials. This review will focus only on the prophylactic strategies that have possible or proven value.

Contrast Media↗
PubMed2003

Pathogenesis of contrast-induced nephropathy: experimental and clinical observations with an emphasis on the role of osmolality.

Experimental studies suggest that the pathogenesis of contrast media nephrotopathy is due to a combination of renal ischemia and direct tubular epithelial cell toxicity. Clinical studies to date have demonstrated a reduction in clinical contrast nephropathy with the introduction of low-osmolar and, more recently, iso-osmolar contrast media. Numerous experimental studies have examined the role of osmolality per se in the pathogenesis of contrast nephropathy, with conflicting results. Whether iso-osmolar contrast media are the least nephrotoxic iodinated contrast media needs to be determined with large prospective randomized clinical trials.

Contrast Media↗