Biomedical subjects

Stefan Catheline

Publications and source records attributed to Stefan Catheline.

3 recordsLinked to original sources

PubMed2003

Transient elastography in anisotropic medium: application to the measurement of slow and fast shear wave speeds in muscles.

From the measurement of a low frequency (50-150 Hz) shear wave speed, transient elastography evaluates the Young's modulus in isotropic soft tissues. In this paper, it is shown that a rod source can generate a low frequency polarized shear strain waves. Consequently this technique allows to study anisotropic medium such as muscle. The evidence of the polarization of low frequency shear strain waves is supported by both numeric simulations and experiments. The numeric simulations are based on theoretical Green's functions in isotropic and anisotropic media (hexagonal system). The experiments in vitro led on beef muscle proves the pertinent of this simple anisotropic pattern. Results in vivo on man biceps shows the existence of slow and fast shear waves as predicted by theory.

Acoustic Stimulation↗

PubMed2002

Shear modulus imaging with 2-D transient elastography.

In previous works, we have shown that time-resolved 2-D transient elastography is a promising technique for characterizing the elasticity of soft tissues. It involves the measurement of the displacements induced by the propagation of low frequency (LF) pulsed shear waves in biological tissues. In this paper, we present a novel apparatus that contains a LF vibrating device surrounding a linear array of 128 ultrasonic transducers that performs ultrafast ultrasonic imaging (up to 10,000 frames/s) and that is able to follow in real time the propagation of a LF shear wave in the human body. The vibrating device is made of two rods, fixed to electromagnetic vibrators, that produce in the ultrasonic image area a large amplitude shear wave. The geometry has been chosen both to enhance the sensitivity and to create a quasi linear shear wave front in the imaging plane. An inversion algorithm is used to recover the shear modulus map from the spatio-temporal data, and the first experimental results obtained from tissue-equivalent materials are presented.

Algorithms↗

PubMed2002

Shear elasticity probe for soft tissues with 1-D transient elastography.

Important tissue parameters such as elasticity can be deduced from the study of the propagation of low frequency shear waves. A new method for measuring the shear velocity in soft tissues is presented in this paper. Unlike conventional transient elastography, in which the ultrasonic transducer and the low frequency vibrator are two separated parts, the new method relies on a probe that associates the vibrator and the transducer, which is built on the axis of the vibrator. This setup is easy to use. The low frequency shear wave is driven by the transducer itself that acts as a piston while it is used in pulse echo mode to acquire ultrasonic lines. The results obtained with the new method are in good agreement with those obtained with the conventional one.

Algorithms↗