Biomedical subjects

Stephen F Brint

Publications and source records attributed to Stephen F Brint.

3 recordsLinked to original sources

PubMed2004

AquaLase: a new technology for cataract extraction.

PURPOSE OF REVIEW: This review describes a completely new technology for removal of the crystalline lens and compares it to currently available instruments. The AquaLase option on the Infiniti Vision System (Alcon Laboratories, Fort Worth, Texas) delivers unique advantages over conventional ultrasound phacoemulsification. RECENT FINDINGS: Incremental improvements have made ultrasonic phacoemulsification safer to the posterior capsule and less likely to create wound burn. AquaLase uses a fundamentally different technology that eliminates the risk of incision burn, is probably less likely to cause posterior capsule rupture than ultrasonic phacoemulsification needles, and is more efficient than laser-based lens removal instruments. SUMMARY: AquaLase is a new technology that offers significant advantages and is likely to find wider application as clinical experience accumulates.

Cataract Extraction↗

PubMed2002

Analysis of elements of interlenticular opacification.

PURPOSE: To report the histopathologic and ultrastructural features of three cases of interlenticular opacification (ILO) between piggyback intraocular lenses. DESIGN: Interventional case series with clinicopathologic correlation. METHODS: Three pairs of acrylic piggyback lenses were explanted due to decrease in visual acuity associated with ILO. Lenses were evaluated with gross and light microscopic examinations in all cases. The anterior lens in one case was examined with scanning electron microscopy and energy dispersive x-ray spectroscopy. RESULTS: The material opacifying the interlenticular space was composed mostly of retained/regenerative cortical material in all cases. From the peripheral interface towards the central interface, the opacifying material changed as the interlenticular space was progressively narrower. The material attached to the peripheral interface, where the interlenticular space was wider, was very thick. At the midperipheral interface, the thick cortical material was broken into multiple globules due to liquefactive degeneration. At the paracentral zone, compression of the globules formed a flat, compact layer of an amorphous material. At the central interface (contact zone), almost no material could be found between the piggyback lenses. CONCLUSIONS: Analyses of ILO cases where all the components of the opacifying material were in situ allowed us to confirm that the pathogenesis of this complication is similar to that of posterior capsule opacification; thus, careful removal of lens epithelial cells and cortical material is mandatory in piggyback implantation.

Acrylic Resins↗

PubMedDate not supplied

Higher order aberrations after LASIK for myopia with alcon and wavelight lasers: a prospective randomized trial.

PURPOSE: To evaluate the differences in higher order aberration outcomes between bilateral wavefront-guided and wavefront-optimized LASIK treatments on two closely matched patient groups 1 and 3 months following surgery. METHODS: Thirty patients were enrolled in the study and randomly assigned to undergo bilateral LASIK with either the Alcon CustomCornea laser system or the WaveLight Allegretto Wave laser system. Standard clinical outcomes such as visual acuity and manifest refraction were evaluated as well as quality of vision measures such as subjective questionnaires and higher order aberrations. All patients completed follow-up examinations for 3 months following surgery. RESULTS: At 1 and 3 months after surgery, the uncorrected visual acuity and the refractive outcome were similar for the two laser platforms, with 90% to 93% eyes being within +/- 0.5 D of intended outcome. At 1 and 3 months the Alcon CustomCornea group had a statistically significant lower amount of induced total higher order aberrations compared to the Allegretto Wave group (P < .05). CONCLUSIONS: LASIK for myopia with the Alcon CustomCornea and WaveLight Allegretto Wave systems is highly effective in terms of refractive outcome and uncorrected visual acuity. However, aberrations were statistically significantly greater after treatment with the WaveLight Allegretto Wave system than with the Alcon CustomCornea.

Adult↗