Biomedical subjects

Stephen M Anthony

Publications and source records attributed to Stephen M Anthony.

2 recordsLinked to original sources

PubMed2006

Single-particle colloid tracking in four dimensions.

Coating a close-packed fluorescent colloid monolayer with a nanometer-thick metal film followed by sonication in liquid produces modulated optical nanoprobes. The metal coating modulates the fluorescence as these structures rotate in suspension, enabling the use of these particles as probes to monitor both rotational and center-of-mass (translational) dynamics in complex environments. Here, we demonstrate methods to simultaneously measure two translational and two rotational degrees of freedom, with excellent agreement to theory. The capability to determine two angles of rotation opens several new avenues of future research.

Journal Article↗

PubMed2006

Rotation in suspension of a rod-shaped colloid.

The simple strategy of coating a closely packed colloid monolayer with a nanometer-thick metal film to connect colloidal spheres and then gently sonicating produces a series of colloid metastructures, including rods and planar sheets. These structures can be fluorescently labeled, which can serve as a probe to monitor their dynamics in complex environments. The metal coating modulates fluorescence emission as these structures rotate in suspension. By analyzing the time sequence of fluorescence images using single-particle tracking techniques, here we measure the rotational dynamics of a rodlike tetramer, quantifying rotation along the long axis.

Journal Article↗