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Steve Cunningham

Publications and source records attributed to Steve Cunningham.

4 recordsLinked to original sources
PubMed2006

The availability and use of oxygen saturation monitoring in primary care in order to assess asthma severity.

INTRODUCTION: The BTS/SIGN guideline recommends oxygen saturation (SaO2) monitoring as an objective measure of acute asthma severity, particularly in children, in both primary and secondary care. We assessed the availability and use of SaO2 monitoring for acute asthma assessment in primary care. METHODS: Fax and telephone questionnaire of Primary Care services in the Edinburgh region to assess use of SaO2 monitoring in the past 24 months, in association with a 24-month retrospective assessment of A&E attendances with acute wheeze. Children over 12 months of age registered with eligible general practices attending A&E with wheeze and/or asthma were included. RESULTS: There were replies from 103 general practices (100%) and eight Out-of-hours cooperatives (100%). Oxygen saturation monitoring was available in four general practices (3.9%) and three Out-of-hours cooperatives (37.5%). 1408 children attended A&E with wheeze/asthma, 721 referred by primary care. Oxygen saturation monitoring was available to 7.9% of A&E attendees from primary care, but documented in only 1.8% of primary care referrals. CONCLUSIONS: SaO2 monitoring is not widely available in primary care and is infrequently used for the assessment of acute asthma. SaO2 measurement as an adjunct to clinical assessment of asthma in primary care needs encouragement.

Adolescent↗
PubMed2003

Hypoxic oxygen fluctuations produce less severe retinopathy than hyperoxic fluctuations in a rat model of retinopathy of prematurity.

The aim of this study was to investigate whether the mean around which arterial oxygen fluctuations take place was important in a unique animal model of oxygen-induced retinopathy. Retinopathy of prematurity (ROP) is associated with fluctuating arterial oxygen. A recent retrospective study suggested that management of high-risk preterm infants at lower oxygen saturations was associated with less severe ROP. Rat pups were raised in a variable oxygen environment around a high (24%), normal (21%) or low (17%) mean inspired oxygen for 14 d. Rat pups raised in the high (24%) mean variable oxygen environment had more retarded retinal vascular development than did rats raised in an environment that fluctuated around 21% mean oxygen. In contrast, rats raised in a lower mean (17%) but still variable oxygen environment had no discernible retinal differences from controls raised in constant room air. Rats raised in a relatively hypoxic but variable oxygen environment develop less severe retinal vascular abnormalities than those raised in variable oxygen around higher oxygen means.

Animals↗