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Biomedical subjects

Steven M Cohen

Publications and source records attributed to Steven M Cohen.

4 recordsLinked to original sources
PubMed2007

Optical coherence tomography findings in nonproliferative group 2a idiopathic juxtafoveal retinal telangiectasis.

PURPOSE: To determine the optical coherence tomography (OCT) findings in eyes with group 2a idiopathic juxtafoveal retinal telangiectasis (IJRT). METHODS: Forty-one eyes of 22 patients with nonproliferative group 2a IJRT were examined. OCT testing including retinal topographic mapping and analysis, and horizontal and vertical line scans, was obtained on each eye. RESULTS: None of the 41 eyes had a thickened foveal center. The average center foveal thickness was 166 microm (31-264 microm). Stage 1 eyes (n = 2) were normal fellow eyes in patients with contralateral group 2a IJRT. Stage 2 eyes (n = 11) all had parafoveolar temporal graying and intraretinal temporal fluorescein leakage, but rarely had photoreceptor disruption (18%) on OCT testing. Stage 3 eyes (n = 14) all had clinical and fluorescein findings similar to or more pronounced than stage 2 eyes. All stage 3 eyes also had one or more foveal cysts at various retinal depths on OCT. Most of these eyes (86%) had photoreceptor disruption and outer retinal atrophy on OCT. Stage 4 eyes (n = 14) all had a black foveal or parafoveolar pigment plaque and intraretinal temporal fluorescein leakage. All stage 4 eyes had a hyper-reflective plaque with shadowing on OCT corresponding to the pigment plaque. Most of these eyes had one or more foveal cysts (64%) and all of these eyes had photoreceptor disruption and outer retinal atrophy. CONCLUSION: OCT helps in the staging of group 2a IJRT and reveals multiple retinal structural abnormalities.

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PubMed2006

Cystoid macular edema after pars plana vitrectomy for retained lens fragments.

PURPOSE: To describe the incidence and clinical course in patients with cystoid macular edema (CME) following pars plana vitrectomy (PPV) for retained lens fragments. SETTING: Retina group, private practice. METHODS: This retrospective study reviewed the medical records of 91 patients who had PPV for retained lens fragments. The patients were followed for at least 6 months. Patients with concomitant eye diseases that adversely affected macular examination or macular function were excluded. RESULTS: Four (8%) of 50 eyes with a sulcus-fixated posterior chamber intraocular lens (PC IOL) implanted at cataract extraction and 19 (46%) of 41 eyes with aphakia or an anterior chamber IOL developed CME (P</=.001, chi-square test). The CME developed a mean of 4 months after PPV. Treatment consisted of steroid eyedrops in all eyes; 17 eyes were also treated with a topical cyclooxygenase inhibitor, and 5 eyes received posterior sub-Tenon's steroid injections. The CME resolved a mean of 2 months after 1 treatment course in 12 eyes, which had a final visual acuity of 20/40 or better. The CME resolved, recurred, and then resolved in 6 eyes. In these eyes, the first incidence lasted a mean of 4 months. The second episode occurred a mean of 5 months after the initial episode resolved and took a mean of 3 months to resolve. Final visual acuity was 20/40 or better in 5 of these eyes. The CME persisted in 5 eyes that were followed for a mean of 30 months. None of these eyes had an acuity of 20/40 or better. CONCLUSIONS: Sulcus placement of a PC IOL at cataract extraction was associated with a reduced risk for CME. The prognosis for eyes that develop CME after PPV for retained lens fragments is guarded. Long-term therapy should be considered because of the high rate of recurrence.

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PubMed2005

Natural history of asymptomatic clinical retinal detachments.

PURPOSE: To determine the natural history of asymptomatic, clinical rhegmatogenous retinal detachment. DESIGN: Single observer, prospective, consecutive, observational case series. METHODS: Consecutive patients were included who were referred to the author's clinical practice with rhegmatogenous retinal detachment extending greater than two disk-diameters posterior to the equator. Patients whose eye had an intraocular procedure within the past year or who had a history of symptomatic retinal detachment in the fellow eye were excluded. Eighteen eyes of 16 patients were followed for an average of 46 months. The main outcome measure was progression of asymptomatic retinal detachment to symptomatic retinal detachment. RESULTS: None of the 18 asymptomatic, clinical, rhegmatogenous retinal detachments became symptomatic. The posterior margin of one retinal detachment slightly progressed 4 months into the study and then stabilized for 4 years and remained asymptomatic. CONCLUSIONS: Asymptomatic, clinical, rhegmatogenous retinal detachments can probably be safely observed for many years.

Adult↗