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Biomedical subjects

Sue Ann Wee

Publications and source records attributed to Sue Ann Wee.

4 recordsLinked to original sources
PubMed2005

Necrobiotic xanthogranuloma.

A 67-year-old man presented with a 13-year history of slowly enlarging yellow-red plaques on the face and lower extremity. A biopsy specimen was consistent with necrobiotic xanthogranuloma. Necrobiotic xanthogranuloma is a slowly progressive histiocytic disease that is associated with paraproteinemia in most cases; however, its pathogenesis remains unclear. Although there is no first-line therapy, anecdotal reports have shown variable benefit with chemotherapeutic agents.

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PubMed2004

Necrobiosis lipoidica.

A 68-year-old woman presented with a 3-year history of asymptomatic, yellow-brown plaques on the lower extremities with trauma-related superficial ulcers. A biopsy specimen was consistent with necrobiosis lipoidica. Necrobiosis lipoidica is a chronic granulomatous dermatitis that is associated with diabetes mellitus; however, its pathogenesis remains unclear. Topical glucocorticoids are first-line therapy; however, no treatment has proven efficacy in double-blind, placebo-controlled studies.

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PubMed2004

Multiple eruptive keratoacanthomas, de novo.

An 89-year-old man presented with the sudden eruption of multiple, erythematous papules and nodules on his lower extremities. A skin biopsy specimen showed keratoacanthoma. After 3 months of treatment with topical imiquimod cream, the keratoacanthomas failed to resolve. We review the different clinical subtypes, histologic features, and treatment options for multiple eruptive keratoacanthomas.

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